Mutational landscape and significance across 12 major cancer types C Kandoth, MD McLellan, F Vandin, K Ye, B Niu, C Lu, M Xie, Q Zhang, ... Nature 502 (7471), 333-339, 2013 | 4952 | 2013 |
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia Cancer Genome Atlas Research Network New England Journal of Medicine 368 (22), 2059-2074, 2013 | 4930 | 2013 |
Recurring mutations found by sequencing an acute myeloid leukemia genome ER Mardis, L Ding, DJ Dooling, DE Larson, MD McLellan, K Chen, ... New England Journal of Medicine 361 (11), 1058-1066, 2009 | 2744 | 2009 |
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing L Ding, TJ Ley, DE Larson, CA Miller, DC Koboldt, JS Welch, JK Ritchey, ... Nature 481 (7382), 506-510, 2012 | 2592 | 2012 |
DNMT3A Mutations in Acute Myeloid Leukemia TJ Ley, L Ding, MJ Walter, MD McLellan, T Lamprecht, DE Larson, ... New England Journal of Medicine 363 (25), 2424-2433, 2010 | 2473 | 2010 |
Age-related mutations associated with clonal hematopoietic expansion and malignancies M Xie, C Lu, J Wang, MD McLellan, KJ Johnson, MC Wendl, ... Nature medicine 20 (12), 1472-1478, 2014 | 2025 | 2014 |
The origin and evolution of mutations in acute myeloid leukemia JS Welch, TJ Ley, DC Link, CA Miller, DE Larson, DC Koboldt, ... Cell 150 (2), 264-278, 2012 | 1894 | 2012 |
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome TJ Ley, ER Mardis, L Ding, B Fulton, MD McLellan, K Chen, D Dooling, ... Nature 456 (7218), 66-72, 2008 | 1614 | 2008 |
Clonal architecture of secondary acute myeloid leukemia MJ Walter, D Shen, L Ding, J Shao, DC Koboldt, K Chen, DE Larson, ... New England Journal of Medicine 366 (12), 1090-1098, 2012 | 1009 | 2012 |
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia TN Wong, G Ramsingh, AL Young, CA Miller, W Touma, JS Welch, ... Nature 518 (7540), 552-555, 2015 | 881 | 2015 |
TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes JS Welch, AA Petti, CA Miller, CC Fronick, M O’Laughlin, RS Fulton, ... New England Journal of Medicine 375 (21), 2023-2036, 2016 | 877 | 2016 |
Recurrent DNMT3A mutations in patients with myelodysplastic syndromes MJ Walter, L Ding, D Shen, J Shao, M Grillot, M McLellan, R Fulton, ... Leukemia 25 (7), 1153-1158, 2011 | 706 | 2011 |
Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes TA Graubert, D Shen, L Ding, T Okeyo-Owuor, CL Lunn, J Shao, K Krysiak, ... Nature genetics 44 (1), 53-57, 2012 | 679 | 2012 |
SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution CA Miller, BS White, ND Dees, M Griffith, JS Welch, OL Griffith, R Vij, ... PLoS computational biology 10 (8), e1003665, 2014 | 515 | 2014 |
Functional heterogeneity of genetically defined subclones in acute myeloid leukemia JM Klco, DH Spencer, CA Miller, M Griffith, TL Lamprecht, M O’Laughlin, ... Cancer cell 25 (3), 379-392, 2014 | 450 | 2014 |
Immune escape of relapsed AML cells after allogeneic transplantation MJ Christopher, AA Petti, MP Rettig, CA Miller, E Chendamarai, ... New England Journal of Medicine 379 (24), 2330-2341, 2018 | 442 | 2018 |
Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia JM Klco, CA Miller, M Griffith, A Petti, DH Spencer, S Ketkar-Kulkarni, ... Jama 314 (8), 811-822, 2015 | 400 | 2015 |
Mutant U2AF1 expression alters hematopoiesis and pre-mRNA splicing in vivo CL Shirai, JN Ley, BS White, S Kim, J Tibbitts, J Shao, M Ndonwi, ... Cancer cell 27 (5), 631-643, 2015 | 344 | 2015 |
Clonal diversity of recurrently mutated genes in myelodysplastic syndromes MJ Walter, D Shen, J Shao, L Ding, BS White, C Kandoth, CA Miller, B Niu, ... Leukemia 27 (6), 1275-1282, 2013 | 336 | 2013 |
Patterns and functional implications of rare germline variants across 12 cancer types C Lu, M Xie, MC Wendl, J Wang, MD McLellan, MDM Leiserson, K Huang, ... Nature communications 6 (1), 10086, 2015 | 316 | 2015 |