| Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP H Zhang, FA Kolb, V Brondani, E Billy, W Filipowicz The EMBO journal, 2002 | 923 | 2002 |
| Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines E Billy, V Brondani, H Zhang, U Müller, W Filipowicz Proceedings of the National Academy of Sciences 98 (25), 14428-14433, 2001 | 621 | 2001 |
| Project DRIVE: a compendium of cancer dependencies and synthetic lethal relationships uncovered by large-scale, deep RNAi screening ER McDonald, A De Weck, MR Schlabach, E Billy, KJ Mavrakis, ... Cell 170 (3), 577-592. e10, 2017 | 615 | 2017 |
| Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5 KJ Mavrakis, ER McDonald III, MR Schlabach, E Billy, GR Hoffman, ... Science 351 (6278), 1208-1213, 2016 | 434 | 2016 |
| CRISPR screens provide a comprehensive assessment of cancer vulnerabilities but generate false-positive hits for highly amplified genomic regions DM Munoz, PJ Cassiani, L Li, E Billy, JM Korn, MD Jones, J Golji, ... Cancer discovery 6 (8), 900-913, 2016 | 378 | 2016 |
| Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization K LaMontagne, A Littlewood-Evans, C Schnell, T O'Reilly, L Wyder, ... Cancer research 66 (1), 221-231, 2006 | 367 | 2006 |
| Open science saves lives: lessons from the COVID-19 pandemic L Besançon, N Peiffer-Smadja, C Segalas, H Jiang, P Masuzzo, C Smout, ... BMC Medical Research Methodology 21 (1), 117, 2021 | 268 | 2021 |
| The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis G Martiny-Baron, P Holzer, E Billy, C Schnell, J Brueggen, M Ferretti, ... Angiogenesis 13, 259-267, 2010 | 141 | 2010 |
| Bms1p, a G-domain-containing protein, associates with Rcl1p and is required for 18S rRNA biogenesis in yeast T WEGIERSKI, E BILLY, F NASR, W FILIPOWICZ Rna 7 (9), 1254-1267, 2001 | 131 | 2001 |
| Rcl1p, the yeast protein similar to the RNA 3′-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis E Billy, T Wegierski, F Nasr, W Filipowicz The EMBO journal 19 (9), 2115-2126, 2000 | 118 | 2000 |
| The tyrosine phosphatase PTPN14 is a negative regulator of YAP activity C Michaloglou, W Lehmann, T Martin, C Delaunay, A Hueber, L Barys, ... PloS one 8 (4), e61916, 2013 | 96 | 2013 |
| Reduced pathological angiogenesis and tumor growth in mice lacking GPR4, a proton sensing receptor L Wyder, T Suply, B Ricoux, E Billy, C Schnell, BU Baumgarten, SM Maira, ... Angiogenesis 14, 533-544, 2011 | 84 | 2011 |
| The human RNA 3′‐terminal phosphate cyclase is a member of a new family of proteins conserved in Eucarya, Bacteria and Archaea P Genschik, E Billy, M Swianiewicz, W Filipowicz The EMBO Journal, 1997 | 82 | 1997 |
| SHP2 inhibition overcomes RTK-mediated pathway reactivation in KRAS-mutant tumors treated with MEK inhibitors H Lu, C Liu, R Velazquez, H Wang, LM Dunkl, M Kazic-Legueux, ... Molecular cancer therapeutics 18 (7), 1323-1334, 2019 | 79 | 2019 |
| Short interfering ribonucleic acid (siRNA) with improved pharmacological properties FJC Natt, E Billy, J Hunziker, CR Schnell US Patent 8,084,600, 2011 | 40 | 2011 |
| Crystal structure of RNA 3′-terminal phosphate cyclase, a ubiquitous enzyme with unusual topology GJ Palm, E Billy, W Filipowicz, A Wlodawer Structure 8 (1), 13-23, 2000 | 38 | 2000 |
| Characterization of the adenylation site in the RNA 3′-terminal phosphate cyclase from Escherichia coli E Billy, D Hess, J Hofsteenge, W Filipowicz Journal of Biological Chemistry 274 (49), 34955-34960, 1999 | 27 | 1999 |
| Maximizing the Efficacy of MAPK-Targeted Treatment in PTENLOF/BRAFMUT Melanoma through PI3K and IGF1R Inhibition B Herkert, A Kauffmann, S Mollé, C Schnell, T Ferrat, H Voshol, J Juengert, ... Cancer research 76 (2), 390-402, 2016 | 21 | 2016 |
| Short interfering ribonucleic acid (siRNA) for oral administration FJC Natt, E Billy, J Hunziker, CR Schnell US Patent 8,344,128, 2013 | 21 | 2013 |
| Correction of copy number induced false positives in CRISPR screens A de Weck, J Golji, MD Jones, JM Korn, E Billy, ER McDonald III, ... PLoS Computational Biology 14 (7), e1006279, 2018 | 20 | 2018 |
