| Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy Y Lai, GD Thomas, Y Yue, HT Yang, D Li, C Long, L Judge, B Bostick, ... The Journal of clinical investigation 119 (3), 624-635, 2009 | 422 | 2009 |
| Efficient in vivo gene expression by trans-splicing adeno-associated viral vectors Y Lai, Y Yue, M Liu, A Ghosh, JF Engelhardt, JS Chamberlain, D Duan Nature biotechnology 23 (11), 1435-1439, 2005 | 247 | 2005 |
| Evidence for the failure of adeno-associated virus serotype 5 to package a viral genome≥ 8.2 kb Y Lai, Y Yue, D Duan Molecular Therapy 18 (1), 75-79, 2010 | 204 | 2010 |
| Vascular endothelial growth factor increases functional β-cell mass by improvement of angiogenesis of isolated human and murine pancreatic islets Y Lai, D Schneider, A Kidszun, I Hauck-Schmalenberger, G Breier, ... Transplantation 79 (11), 1530-1536, 2005 | 189 | 2005 |
| A hybrid vector system expands adeno-associated viral vector packaging capacity in a transgene-independent manner A Ghosh, Y Yue, Y Lai, D Duan Molecular therapy 16 (1), 124-130, 2008 | 174 | 2008 |
| Adeno-Associated Virus Serotype-9 Microdystrophin Gene Therapy Ameliorates Electrocardiographic Abnormalities in mdx Mice B Bostick, Y Yue, Y Lai, C Long, D Li, D Duan Human gene therapy 19 (8), 851-856, 2008 | 113 | 2008 |
| Nitrosative stress elicited by nNOSµ delocalization inhibits muscle force in dystrophin‐null mice D Li, Y Yue, Y Lai, CH Hakim, D Duan The Journal of pathology 223 (1), 88-98, 2011 | 112 | 2011 |
| Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin D Li, A Bareja, L Judge, Y Yue, Y Lai, R Fairclough, KE Davies, ... Journal of cell science 123 (12), 2008-2013, 2010 | 112 | 2010 |
| α2 and α3 helices of dystrophin R16 and R17 frame a microdomain in the α1 helix of dystrophin R17 for neuronal NOS binding Y Lai, J Zhao, Y Yue, D Duan Proceedings of the National Academy of Sciences 110 (2), 525-530, 2013 | 108 | 2013 |
| Ischaemia is linked to inflammation and induction of angiogenesis in pancreatic islets T Linn, J Schmitz, I Hauck-Schmalenberger, Y Lai, RG Bretzel, ... Clinical & Experimental Immunology 144 (2), 179-187, 2006 | 103 | 2006 |
| AAV micro-dystrophin gene therapy alleviates stress-induced cardiac death but not myocardial fibrosis in> 21-m-old mdx mice, an end-stage model of Duchenne muscular dystrophy … B Bostick, JH Shin, Y Yue, NB Wasala, Y Lai, D Duan Journal of molecular and cellular cardiology 53 (2), 217-222, 2012 | 79 | 2012 |
| A simplified immune suppression scheme leads to persistent micro-dystrophin expression in Duchenne muscular dystrophy dogs JH Shin, Y Yue, A Srivastava, B Smith, Y Lai, D Duan Human gene therapy 23 (2), 202-209, 2012 | 64 | 2012 |
| Dystrophin contains multiple independent membrane-binding domains J Zhao, K Kodippili, Y Yue, CH Hakim, L Wasala, X Pan, K Zhang, ... Human molecular genetics 25 (17), 3647-3653, 2016 | 60 | 2016 |
| Trans-splicing adeno-associated viral vector-mediated gene therapy is limited by the accumulation of spliced mRNA but not by dual vector coinfection efficiency Z Xu, Y Yue, Y Lai, C Ye, J Qiu, DJ Pintel, D Duan Human gene therapy 15 (9), 896-905, 2004 | 58 | 2004 |
| Design of AAV vectors for delivery of large or multiple transgenes A Patel, J Zhao, D Duan, Y Lai Adeno-Associated Virus Vectors: Design and Delivery, 19-33, 2019 | 55 | 2019 |
| Synthetic intron improves transduction efficiency of trans-splicing adeno-associated viral vectors Y Lai, Y Yue, M Liu, D Duan Human gene therapy 17 (10), 1036-1042, 2006 | 46 | 2006 |
| Partial restoration of cardiac function with ΔPDZ nNOS in aged mdx model of Duchenne cardiomyopathy Y Lai, J Zhao, Y Yue, NB Wasala, D Duan Human Molecular Genetics 23 (12), 3189-3199, 2014 | 39 | 2014 |
| Activation of NFκB dependent apoptotic pathway in pancreatic islet cells by hypoxia Y Lai, H Brandhorst, H Hossain, A Bierhaus, C Chen, RG Bretzel, T Linn Islets 1 (1), 19-25, 2009 | 35 | 2009 |
| Progress in gene therapy of dystrophic heart disease Y Lai, D Duan Gene therapy 19 (6), 678-685, 2012 | 34 | 2012 |
| Genetic modification of cells for transplantation Y Lai, I Drobinskaya, E Kolossov, C Chen, T Linn Advanced Drug Delivery Reviews 60 (2), 146-159, 2008 | 32 | 2008 |
