The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade B Coutard, C Valle, X De Lamballerie, B Canard, NG Seidah, E Decroly Antiviral research 176, 104742, 2020 | 1988 | 2020 |
One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities L Subissi, CC Posthuma, A Collet, JC Zevenhoven-Dobbe, ... Proceedings of the National Academy of Sciences 111 (37), E3900-E3909, 2014 | 646 | 2014 |
The nonstructural proteins directing coronavirus RNA synthesis and processing EJ Snijder, E Decroly, J Ziebuhr Advances in virus research 96, 59-126, 2016 | 633 | 2016 |
Conventional and unconventional mechanisms for capping viral mRNA E Decroly, F Ferron, J Lescar, B Canard Nature Reviews Microbiology 10 (1), 51-65, 2012 | 508 | 2012 |
Structure and functionality in flavivirus NS-proteins: perspectives for drug design M Bollati, K Alvarez, R Assenberg, C Baronti, B Canard, S Cook, ... Antiviral research 87 (2), 125-148, 2010 | 442 | 2010 |
In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication F Touret, M Gilles, K Barral, A Nougairède, J Van Helden, E Decroly, ... Scientific reports 10 (1), 13093, 2020 | 411 | 2020 |
In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation M Bouvet, C Debarnot, I Imbert, B Selisko, EJ Snijder, B Canard, ... PLoS pathogens 6 (4), e1000863, 2010 | 407 | 2010 |
Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA F Ferron, L Subissi, AT Silveira De Morais, NTT Le, M Sevajol, L Gluais, ... Proceedings of the National Academy of Sciences 115 (2), E162-E171, 2018 | 399 | 2018 |
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-O-methyltransferase nsp10/nsp16 complex E Decroly, C Debarnot, F Ferron, M Bouvet, B Coutard, I Imbert, L Gluais, ... PLoS pathogens 7 (5), e1002059, 2011 | 365 | 2011 |
RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex M Bouvet, I Imbert, L Subissi, L Gluais, B Canard, E Decroly Proceedings of the National Academy of Sciences 109 (24), 9372-9377, 2012 | 360 | 2012 |
Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites A Shannon, NTT Le, B Selisko, C Eydoux, K Alvarez, JC Guillemot, ... Antiviral research 178, 104793, 2020 | 336 | 2020 |
Coronavirus Nonstructural Protein 16 Is a Cap-0 Binding Enzyme Possessing (Nucleoside-2′O)-Methyltransferase Activity E Decroly, I Imbert, B Coutard, M Bouvet, B Selisko, K Alvarez, ... Journal of virology 82 (16), 8071-8084, 2008 | 298 | 2008 |
Maturation of HIV envelope glycoprotein precursors by cellular endoproteases M Moulard, E Decroly Biochimica et Biophysica Acta (BBA)-Reviews on Biomembranes 1469 (3), 121-132, 2000 | 273 | 2000 |
Insights into RNA synthesis, capping, and proofreading mechanisms of SARS-coronavirus M Sevajol, L Subissi, E Decroly, B Canard, I Imbert Virus research 194, 90-99, 2014 | 239 | 2014 |
Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes M Bouvet, A Lugari, CC Posthuma, JC Zevenhoven, S Bernard, S Betzi, ... Journal of Biological Chemistry 289 (37), 25783-25796, 2014 | 239 | 2014 |
Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis A Shannon, B Selisko, NTT Le, J Huchting, F Touret, G Piorkowski, ... Nature communications 11 (1), 4682, 2020 | 230 | 2020 |
SARS-CoV ORF1b-encoded nonstructural proteins 12–16: replicative enzymes as antiviral targets L Subissi, I Imbert, F Ferron, A Collet, B Coutard, E Decroly, B Canard Antiviral research 101, 122-130, 2014 | 218 | 2014 |
The pore-forming toxin proaerolysin is activated by furin L Abrami, M Fivaz, E Decroly, NG Seidah, F Jean, G Thomas, SH Leppla, ... Journal of Biological Chemistry 273 (49), 32656-32661, 1998 | 198 | 1998 |
FTSJ3 is an RNA 2′-O-methyltransferase recruited by HIV to avoid innate immune sensing M Ringeard, V Marchand, E Decroly, Y Motorin, Y Bennasser Nature 565 (7740), 500-504, 2019 | 193 | 2019 |
The convertases furin and PC1 can both cleave the human immunodeficiency virus (HIV)-1 envelope glycoprotein gp160 into gp120 (HIV-1 SU) and gp41 (HIV-I TM). E Decroly, M Vandenbranden, JM Ruysschaert, J Cogniaux, GS Jacob, ... Journal of Biological Chemistry 269 (16), 12240-12247, 1994 | 185 | 1994 |