| Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway M Altun, HC Besche, HS Overkleeft, R Piccirillo, MJ Edelmann, ... Journal of Biological Chemistry 285 (51), 39597-39608, 2010 | 264 | 2010 |
| Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening A Peth, HC Besche, AL Goldberg Molecular cell 36 (5), 794-804, 2009 | 259 | 2009 |
| Cancer vulnerabilities unveiled by genomic loss D Nijhawan, TI Zack, Y Ren, MR Strickland, R Lamothe, SE Schumacher, ... Cell 150 (4), 842-854, 2012 | 246 | 2012 |
| Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiquitin-like domain from HHR23B reveals novel proteasome-associated proteins HC Besche, W Haas, SP Gygi, AL Goldberg Biochemistry 48 (11), 2538-2549, 2009 | 207 | 2009 |
| Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugates HC Besche, Z Sha, NV Kukushkin, A Peth, EM Hock, W Kim, S Gygi, ... The EMBO journal 33 (10), 1159-1176, 2014 | 192 | 2014 |
| Characterization of the brain 26S proteasome and its interacting proteins HC Tai, H Besche, AL Goldberg, EM Schuman Frontiers in molecular neuroscience 3, 1236, 2010 | 171 | 2010 |
| Getting to first base in proteasome assembly HC Besche, A Peth, AL Goldberg Cell 138 (1), 25-28, 2009 | 92 | 2009 |
| The Harvard medical school pathways curriculum: Reimagining developmentally appropriate medical education for contemporary learners RM Schwartzstein, JL Dienstag, RW King, BS Chang, JG Flanagan, ... Academic Medicine 95 (11), 1687-1695, 2020 | 56 | 2020 |
| Mutational analysis of conserved AAA+ residues in the archaeal Lon protease from Thermoplasma acidophilum H Besche, N Tamura, T Tamura, P Zwickl FEBS letters 574 (1-3), 161-166, 2004 | 53 | 2004 |
| Affinity purification of mammalian 26S proteasomes using an ubiquitin-like domain HC Besche, AL Goldberg Ubiquitin Family Modifiers and the Proteasome: Reviews and Protocols, 423-432, 2012 | 38 | 2012 |
| Twelve tips for the production of digital chalk-talk videos J Rana, H Besche, B Cockrill Medical Teacher 39 (6), 653-659, 2017 | 35 | 2017 |
| The Thermoplasma acidophilum Lon protease has a Ser‐Lys dyad active site H Besche, P Zwickl European journal of biochemistry 271 (22), 4361-4365, 2004 | 29 | 2004 |
| Front. Mol. Neurosci. HC Tai, H Besche, AL Goldberg, EM Schuman | 18 | 2010 |
| A hierarchy of needs for remote undergraduate medical education: lessons from the medical student experience HC Besche, S Onorato, S Pelletier, S Ashrafzadeh, A Joshi, B Nelsen, ... BMC Medical Education 22 (1), 423, 2022 | 11 | 2022 |
| Understanding and optimizing group dynamics in case-based collaborative learning M Kochis, D Kamin, B Cockrill, H Besche Medical science educator 31 (6), 1779-1788, 2021 | 9 | 2021 |
| First-year medical students’ perceptions of a self-regulated learning-informed intervention: an exploratory study T Boyd, H Besche, R Goldhammer, A Alblooshi, BI Coleman BMC Medical Education 22 (1), 821, 2022 | 6 | 2022 |
| Ensuring equitable access to remote learning during the COVID-19 pandemic H Besche, AW Schwartz, B Cockrill Academic Medicine 96 (5), e19-e20, 2021 | 6 | 2021 |
| Bayesian mixed effects model and data visualization for understanding item response time and response order in open online assessment Y Liu, A Béliveau, H Besche, AD Wu, X Zhang, M Stefan, J Gutlerner, ... Frontiers in Education 5, 607260, 2021 | 6 | 2021 |
| Using cognitive load theory to evaluate and improve preparatory materials and study time for the flipped classroom K Fischer, AM Sullivan, AP Cohen, RW King, BA Cockrill, HC Besche BMC Medical Education 23 (1), 345, 2023 | 3 | 2023 |
| Advanced integrated science courses: building a skill set to engage with the interface of research and medicine EM Miloslavsky, HC Besche, SB Calderwood, BS Chang, JL Dienstag, ... Academic Medicine 97 (10), 1467-1473, 2022 | 3 | 2022 |
