Biofilm formation mechanisms and targets for developing antibiofilm agents N Rabin, Y Zheng, C Opoku-Temeng, Y Du, E Bonsu, HO Sintim Future medicinal chemistry 7 (4), 493-512, 2015 | 786 | 2015 |
Isothermal amplified detection of DNA and RNA L Yan, J Zhou, Y Zheng, AS Gamson, BT Roembke, S Nakayama, ... Molecular BioSystems 10 (5), 970-1003, 2014 | 473 | 2014 |
Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP,(p) ppGpp signaling in bacteria and implications in pathogenesis D Kalia, G Merey, S Nakayama, Y Zheng, J Zhou, Y Luo, M Guo, ... Chemical Society Reviews 42 (1), 305-341, 2013 | 422 | 2013 |
Agents that inhibit bacterial biofilm formation N Rabin, Y Zheng, C Opoku-Temeng, Y Du, E Bonsu, HO Sintim Future medicinal chemistry 7 (5), 647-671, 2015 | 315 | 2015 |
Cyclic dinucleotide, c-di-GMP, c-di-AMP, cGAMP signalings have come of age to be inhibited with small molecules HO Sintim, C Opoku-Temeng, J Zhou, Y Zheng, J Su Chemical Communications, 2016 | 101 | 2016 |
Inhibition of innate immune cytosolic surveillance by an M. tuberculosis phosphodiesterase RJ Dey, B Dey, Y Zheng, LS Cheung, J Zhou, D Sayre, P Kumar, H Guo, ... Nature Chemical Biology, 2016 | 92 | 2016 |
Small molecule inhibitors of AI-2 signaling in bacteria: state-of-the-art and future perspectives for anti-quorum sensing agents M Guo, S Gamby, Y Zheng, HO Sintim International journal of molecular sciences 14 (9), 17694-17728, 2013 | 88 | 2013 |
Inhibition of P. aeruginosa c-di-GMP phosphodiesterase RocR and swarming motility by a benzoisothiazolinone derivative Y Zheng, G Tsuji, C Opoku-Temeng, HO Sintim Chemical Science, 2016 | 55 | 2016 |
Unexpected complex formation between coralyne and cyclic diadenosine monophosphate providing a simple fluorescent turn-on assay to detect this bacterial second messenger J Zhou, DA Sayre, Y Zheng, H Szmacinski, HO Sintim Analytical chemistry 86 (5), 2412-2420, 2014 | 46 | 2014 |
Identification of bromophenol thiohydantoin as an inhibitor of DisA, a c-di-AMP synthase, from a 1000 compound library, using the coralyne assay Y Zheng, J Zhou, DA Sayre, HO Sintim Chem. Commun. 50 (76), 11234-11237, 2014 | 45 | 2014 |
A cyclic dinucleotide containing 2-aminopurine is a general fluorescent sensor for c-di-GMP and 3′, 3′-cGAMP BT Roembke, J Zhou, Y Zheng, D Sayre, A Lizardo, L Bernard, HO Sintim Molecular BioSystems 10 (6), 1568-1575, 2014 | 29 | 2014 |
Geminal dihalogen isosteric replacement in hydrated AI-2 affords potent quorum sensing modulators M Guo, Y Zheng, JL Terell, M Ad, C Opoku-Temeng, WE Bentley, ... Chemical Communications 51 (13), 2617-2620, 2015 | 15 | 2015 |
Structure–activity relationship studies of c-di-AMP synthase inhibitor, bromophenol-thiohydantoin Y Zheng, J Zhou, SM Cooper, C Opoku-Temeng, AM De Brito, HO Sintim Tetrahedron, 2015 | 11 | 2015 |
3-Aminooxazolidinone AHL analogs as hydrolytically-stable quorum sensing agonists in Gram-negative bacteria M Guo, Y Zheng, R Starks, C Opoku-Temeng, X Ma, HO Sintim MedChemComm 6 (6), 1086-1092, 2015 | 11 | 2015 |
Supramolecular polymer formation by cyclic dinucleotides and intercalators affects dinucleotide enzymatic processing S Nakayama, J Zhou, Y Zheng, H Szmacinski, HO Sintim Future Science OA 2 (1), 2016 | 10 | 2016 |
Molecular Insights into How Ligands Activate or Inactivate LasR Y Zheng, HO Sintim Chemistry & biology 21 (10), 1261-1263, 2014 | 10 | 2014 |
Biofilm formation mechanisms and targets for developing antibiofilm agents (vol 7, pg 493, 2015) N Rabin, Y Zheng, C Opoku-Temeng, Y Du, E Bonsu, HO Sintim FUTURE MEDICINAL CHEMISTRY 7 (10), 1362-1362, 2015 | 6 | 2015 |
Inhibiting bacterial biofilm and toxin production with new anti-quorum sensing agents M Guo, Y Zheng, HO Sintim ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247, 2014 | | 2014 |
“Rolling out” High‐Molecular‐Weight Proteins, which Contain Repeating Polypeptide Motif, by Using Rolling Circle Amplification Y Zheng, HO Sintim ChemBioChem 14 (15), 1929-1930, 2013 | | 2013 |