Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA KC Keiler, PRH Waller, RT Sauer Science 271 (5251), 990-993, 1996 | 1417 | 1996 |
Biology of trans-Translation KC Keiler Annu. Rev. Microbiol. 62, 133-151, 2008 | 299 | 2008 |
Tsp: a tail-specific protease that selectively degrades proteins with nonpolar C termini. KR Silber, KC Keiler, RT Sauer Proceedings of the National Academy of Sciences 89 (1), 295-299, 1992 | 263 | 1992 |
tmRNAs that encode proteolysis-inducing tags are found in all known bacterial genomes: A two-piece tmRNA functions in Caulobacter KC Keiler, L Shapiro, KP Williams Proceedings of the National Academy of Sciences 97 (14), 7778-7783, 2000 | 208 | 2000 |
Mechanisms of ribosome rescue in bacteria KC Keiler Nature Reviews Microbiology 13 (5), 285-297, 2015 | 207 | 2015 |
Sequence determinants of C-terminal substrate recognition by the Tsp protease KC Keiler, RT Sauer Journal of Biological Chemistry 271 (5), 2589-2593, 1996 | 138 | 1996 |
Identification of active site residues of the Tsp protease KC Keiler, RT Sauer Journal of Biological Chemistry 270 (48), 28864-28868, 1995 | 115 | 1995 |
tmRNA Is Required for Correct Timing of DNA Replication in Caulobacter crescentus KC Keiler, L Shapiro Journal of bacteriology 185 (2), 573-580, 2003 | 112 | 2003 |
Beyond ribosome rescue: tmRNA and co-translational processes CS Hayes, KC Keiler FEBS letters 584 (2), 413-419, 2010 | 98 | 2010 |
C‐terminal specific protein degradation: activity and substrate specificity of the Tsp protease KC Keiler, KR Silber, RT Sauer, KM Downard, IA Papayannopoulos, ... Protein Science 4 (8), 1507-1515, 1995 | 96 | 1995 |
Small molecule inhibitors of trans-translation have broad-spectrum antibiotic activity NS Ramadoss, JN Alumasa, L Cheng, Y Wang, S Li, BS Chambers, ... Proceedings of the National Academy of Sciences 110 (25), 10282-10287, 2013 | 90 | 2013 |
Discovery of antibacterial cyclic peptides that inhibit the ClpXP protease L Cheng, TA Naumann, AR Horswill, SJ Hong, BJ Venters, JW Tomsho, ... Protein Science 16 (8), 1535-1542, 2007 | 90 | 2007 |
Anti-tubercular Activity of Pyrazinamide is Independent of trans-Translation and RpsA NA Dillon, ND Peterson, HA Feaga, KC Keiler, AD Baughn Scientific reports 7 (1), 6135, 2017 | 81 | 2017 |
Resolving nonstop translation complexes is a matter of life or death KC Keiler, HA Feaga Journal of bacteriology 196 (12), 2123-2130, 2014 | 81 | 2014 |
Subcellular localization of a bacterial regulatory RNA JH Russell, KC Keiler Proceedings of the National Academy of Sciences 106 (38), 16405-16409, 2009 | 76 | 2009 |
Cell cycle‐regulated degradation of tmRNA is controlled by RNase R and SmpB SJ Hong, QA Tran, KC Keiler Molecular microbiology 57 (2), 565-575, 2005 | 76 | 2005 |
Pharmacological inhibition of the ClpXP protease increases bacterial susceptibility to host cathelicidin antimicrobial peptides and cell envelope-active antibiotics SM McGillivray, DN Tran, NS Ramadoss, JN Alumasa, CY Okumura, ... Antimicrobial agents and chemotherapy 56 (4), 1854-1861, 2012 | 69 | 2012 |
tmRNA in Caulobacter crescentus Is Cell Cycle Regulated by Temporally Controlled Transcription and RNA Degradation KC Keiler, L Shapiro Journal of bacteriology 185 (6), 1825-1830, 2003 | 59 | 2003 |
Physiology of tmRNA: what gets tagged and why? KC Keiler Current opinion in microbiology 10 (2), 169-175, 2007 | 54 | 2007 |
Bioresponsive peptide-polysaccharide nanogels—A versatile delivery system to augment the utility of bioactive cargo AW Simonson, A Lawanprasert, TDP Goralski, KC Keiler, SH Medina Nanomedicine: Nanotechnology, Biology and Medicine 17, 391-400, 2019 | 47 | 2019 |