An engineered protein antagonist of K-Ras/B-Raf interaction MJ Kauke, MW Traxlmayr, JA Parker, JD Kiefer, R Knihtila, J McGee, ... Scientific reports 7 (1), 5831, 2017 | 67 | 2017 |
Anti-human CD117 CAR T-cells efficiently eliminate healthy and malignant CD117-expressing hematopoietic cells R Myburgh, JD Kiefer, NF Russkamp, CF Magnani, N Nuñez, A Simonis, ... Leukemia 34 (10), 2688-2703, 2020 | 65 | 2020 |
Strong enrichment of aromatic residues in binding sites from a charge-neutralized hyperthermostable Sso7d scaffold library MW Traxlmayr, JD Kiefer, RR Srinivas, E Lobner, AW Tisdale, NK Mehta, ... Journal of Biological Chemistry 291 (43), 22496-22508, 2016 | 62 | 2016 |
Immunocytokines and bispecific antibodies: two complementary strategies for the selective activation of immune cells at the tumor site JD Kiefer, D Neri Immunological reviews 270 (1), 178-192, 2016 | 47 | 2016 |
Quantitative and qualitative analysis of humoral immunity reveals continued and personalized evolution in chronic viral infection NJ Kräutler, A Yermanos, A Pedrioli, SPM Welten, D Lorgé, U Greczmiel, ... Cell reports 30 (4), 997-1012. e6, 2020 | 35 | 2020 |
Anti-CD117 immunotherapy to eliminate hematopoietic and leukemia stem cells NF Russkamp, R Myburgh, JD Kiefer, D Neri, MG Manz Experimental Hematology 95, 31-45, 2021 | 18 | 2021 |
Targeted delivery of TNF potentiates the antibody-dependent cell-mediated cytotoxicity of an anti-melanoma immunoglobulin P Murer, JD Kiefer, L Plüss, M Matasci, SL Blümich, M Stringhini, D Neri Journal of Investigative Dermatology 139 (6), 1339-1348, 2019 | 16 | 2019 |
Design principles for SuCESsFul biosensors: Specific fluorophore/analyte binding and minimization of fluorophore/scaffold interactions S De Picciotto, PM Dickson, MW Traxlmayr, BS Marques, E Socher, ... Journal of molecular biology 428 (20), 4228-4241, 2016 | 15 | 2016 |
A Fibrin-Specific Monoclonal Antibody from a Designed Phage Display Library Inhibits Clot Formation and Localizes to Tumors In Vivo A Putelli, JD Kiefer, M Zadory, M Matasci, D Neri Journal of molecular biology 426 (21), 3606-3618, 2014 | 15 | 2014 |
Generation of “LYmph Node Derived Antibody Libraries”(LYNDAL) for selecting fully human antibody fragments with therapeutic potential P Diebolder, A Keller, S Haase, A Schlegelmilch, JD Kiefer, T Karimi, ... MAbs 6 (1), 130-142, 2014 | 14 | 2014 |
Structures of designed armadillo repeat proteins binding to peptides fused to globular domains S Hansen, JD Kiefer, C Madhurantakam, PRE Mittl, A Plückthun Protein Science 26 (10), 1942-1952, 2017 | 13 | 2017 |
Anti-human CD117 CAR T-cells efficiently eliminate hematopoietic stem and CD117-positive AML cells R Myburgh, J Kiefer, NF Russkamp, A Simonis, S Pfister, CM Wilk, ... Blood 132, 4063, 2018 | 4 | 2018 |
BISPECIFIC BINDING AGENT THAT BINDS TO CD117/c-KIT AND CD3 J Kiefer, R Myburgh, M Manz, D Neri US Patent App. 17/640,412, 2022 | 1 | 2022 |
A bispecific antibody targeting CD117 and CD3 enables T cell mediated killing of CD117-expressing healthy and malignant hematopoietic cells JD Kiefer, R Myburgh, NF Russkamp, L Volta, A Guggisberg, ... Blood 138, 2354, 2021 | 1 | 2021 |
Bispecific binding agent that binds to CD117/c-KIT and CD3 J KIEFER, R MYBURGH, M Manz, D Neri | | 2021 |
Treating Acute Myeloid Leukemia with Novel Antibody-Based Therapies JD Kiefer ETH Zurich, 2019 | | 2019 |
Generation of mouse CAR T-cells for the depletion of cKIT-positive hematopoietic cells N Russkamp, R Myburgh, J Kiefer, D Neri, M Manz SWISS MEDICAL WEEKLY 148, 23S-23S, 2018 | | 2018 |