Recent advances in CRISPR/Cas9 delivery strategies BH Yip Biomolecules 10 (6), 839, 2020 | 239 | 2020 |
Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells H Dolatshad, A Pellagatti, M Fernandez-Mercado, BH Yip, L Malcovati, ... Leukemia 29 (5), 1092-1103, 2015 | 235 | 2015 |
Cryptic splicing events in the iron transporter ABCB7 and other key target genes in SF3B1-mutant myelodysplastic syndromes H Dolatshad, A Pellagatti, FG Liberante, M Llorian, E Repapi, V Steeples, ... Leukemia 30 (12), 2322-2331, 2016 | 143 | 2016 |
The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes BH Yip, V Steeples, E Repapi, RN Armstrong, M Llorian, S Roy, J Shaw, ... The Journal of clinical investigation 127 (6), 2206-2221, 2017 | 108 | 2017 |
Production of lentiviral vectors using suspension cells grown in serum-free media M Bauler, JK Roberts, CC Wu, B Fan, F Ferrara, BH Yip, S Diao, YI Kim, ... Molecular Therapy-Methods & Clinical Development 17, 58-68, 2020 | 95 | 2020 |
Mutation patterns of 16 genes in primary and secondary acute myeloid leukemia (AML) with normal cytogenetics M Fernandez-Mercado, BH Yip, A Pellagatti, C Davies, MJ Larrayoz, ... Public Library of Science 7 (8), e42334, 2012 | 78 | 2012 |
ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts S Valletta, H Dolatshad, M Bartenstein, BH Yip, E Bello, S Gordon, Y Yu, ... Oncotarget 6 (42), 44061, 2015 | 77 | 2015 |
DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3 RS Bhansali, M Rammohan, P Lee, AP Laurent, Q Wen, P Suraneni, ... The Journal of Clinical Investigation 131 (1), 2021 | 66 | 2021 |
TP53 suppression promotes erythropoiesis in del (5q) MDS, suggesting a targeted therapeutic strategy in lenalidomide-resistant patients G Caceres, K McGraw, BH Yip, A Pellagatti, J Johnson, L Zhang, K Liu, ... Proceedings of the National Academy of Sciences 110 (40), 16127-16132, 2013 | 63 | 2013 |
Activation of the mTOR pathway by the amino acid L-leucine in the 5q-syndrome and other ribosomopathies J Boultwood, BH Yip, C Vuppusetty, A Pellagatti, JS Wainscoat Advances in biological regulation 53 (1), 8-17, 2013 | 51 | 2013 |
The role of splicing factor mutations in the pathogenesis of the myelodysplastic syndromes J Boultwood, H Dolatshad, SS Varanasi, BH Yip, A Pellagatti Advances in biological regulation 54, 153-161, 2014 | 44 | 2014 |
Silencing of ASXL1 impairs the granulomonocytic lineage potential of human CD34+ progenitor cells C Davies, BH Yip, M Fernandez‐Mercado, PS Woll, X Agirre, F Prosper, ... British journal of haematology 160 (6), 842-850, 2013 | 30 | 2013 |
Mixed lineage leukemia protein in normal and leukemic stem cells BH Yip, CWE So Experimental Biology and Medicine 238 (3), 315-323, 2013 | 28 | 2013 |
Application of genome editing technologies to the study and treatment of hematological disease A Pellagatti, H Dolatshad, BH Yip, S Valletta, J Boultwood Advances in biological regulation 60, 122-134, 2016 | 27 | 2016 |
Impact of splicing factor mutations on pre-mRNA splicing in the myelodysplastic syndromes B Ham Yip, H Dolatshad, S Roy, A Pellagatti, J Boultwood Current Pharmaceutical Design 22 (16), 2333-2344, 2016 | 22 | 2016 |
Effects of L-leucine in 5q-syndrome and other RPS14-deficient erythroblasts BH Yip, A Pellagatti, C Vuppusetty, A Giagounidis, U Germing, ... Leukemia 26 (9), 2154-2158, 2012 | 22 | 2012 |
PRR14L mutations are associated with chromosome 22 acquired uniparental disomy, age-related clonal hematopoiesis and myeloid neoplasia A Chase, A Pellagatti, S Singh, J Score, WJ Tapper, F Lin, Y Hoade, ... Leukemia 33 (5), 1184-1194, 2019 | 12 | 2019 |
Activation of the mTOR signaling pathway by L-leucine in 5q-syndrome and other RPS14-deficient erythroblasts BH Yip, C Vuppusetty, M Attwood, A Giagounidis, U Germing, ... Leukemia 27 (8), 1760-1763, 2013 | 11 | 2013 |
B cell class switch recombination is regulated by DYRK1A through MSH6 phosphorylation L Stoler-Barak, E Harris, A Peres, H Hezroni, M Kuka, P Di Lucia, ... Nature communications 14 (1), 1462, 2023 | 5 | 2023 |
L-leucine increases translation of RPS14 and LARP1 in erythroblasts from del (5q) myelodysplastic syndrome patients E Bello, J Kerry, S Singh, BH Yip, R Kušec, S Killick, S Raynaud, ... haematologica 103 (11), e496, 2018 | 5 | 2018 |