Carvedilol and its new analogs suppress arrhythmogenic store overload–induced Ca2+ release Q Zhou, J Xiao, D Jiang, R Wang, K Vembaiyan, A Wang, CD Smith, C Xie, ... Nature medicine 17 (8), 1003-1009, 2011 | 286 | 2011 |
Caffeine induces Ca2+ release by reducing the threshold for luminal Ca2+ activation of the ryanodine receptor H Kong, PP Jones, A Koop, L Zhang, HJ Duff, SRW Chen Biochemical Journal 414 (3), 441-452, 2008 | 235 | 2008 |
The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias W Chen, R Wang, B Chen, X Zhong, H Kong, Y Bai, Q Zhou, C Xie, ... Nature medicine 20 (2), 184-192, 2014 | 208 | 2014 |
Removal of FKBP12. 6 does not alter the conductance and activation of the cardiac ryanodine receptor or the susceptibility to stress-induced ventricular arrhythmias J Xiao, X Tian, PP Jones, J Bolstad, H Kong, R Wang, L Zhang, HJ Duff, ... Journal of Biological Chemistry 282 (48), 34828-34838, 2007 | 132 | 2007 |
Endoplasmic reticulum Ca2+ measurements reveal that the cardiac ryanodine receptor mutations linked to cardiac arrhythmia and sudden death alter the threshold for store … PP Jones, D Jiang, J Bolstad, DJ Hunt, L Zhang, N Demaurex, SRW Chen Biochemical Journal 412 (1), 171-178, 2008 | 110 | 2008 |
Functional consequence of protein kinase A-dependent phosphorylation of the cardiac ryanodine receptor: sensitization of store overload-induced Ca2+ release B Xiao, X Tian, W Xie, PP Jones, S Cai, X Wang, D Jiang, H Kong, ... Journal of Biological Chemistry 282 (41), 30256-30264, 2007 | 107 | 2007 |
Phosphodiesterase 4D Regulates Baseline Sarcoplasmic Reticulum Ca2+ Release and Cardiac Contractility, Independently of L-Type Ca2+ Current S Beca, PB Helli, JA Simpson, D Zhao, GP Farman, PP Jones, X Tian, ... Circulation research 109 (9), 1024-1030, 2011 | 105 | 2011 |
K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]ryanodine binding to RyR2 irrespective of FKBP12.6 association DJ Hunt, PP Jones, R Wang, W Chen, J Bolstad, K Chen, Y Shimoni, ... Biochemical Journal 404 (3), 431-438, 2007 | 104 | 2007 |
Phospholamban Knockout Breaks Arrhythmogenic Ca2+ Waves and Suppresses Catecholaminergic Polymorphic Ventricular Tachycardia in Mice Y Bai, PP Jones, J Guo, X Zhong, RB Clark, Q Zhou, R Wang, ... Circulation research 113 (5), 517-526, 2013 | 86 | 2013 |
Intravascular pressure augments cerebral arterial constriction by inducing voltage‐insensitive Ca2+ waves RE Mufti, SE Brett, CHT Tran, R Abd El‐Rahman, Y Anfinogenova, ... The Journal of physiology 588 (20), 3983-4005, 2010 | 77 | 2010 |
Etiology-dependent impairment of diastolic cardiomyocyte calcium homeostasis in heart failure with preserved ejection fraction M Frisk, C Le, X Shen, ÅT Røe, Y Hou, O Manfra, GJJ Silva, I van Hout, ... Journal of the American College of Cardiology 77 (4), 405-419, 2021 | 76 | 2021 |
Reduced threshold for luminal Ca2+ activation of RyR1 underlies a causal mechanism of porcine malignant hyperthermia D Jiang, W Chen, J Xiao, R Wang, H Kong, PP Jones, L Zhang, B Fruen, ... Journal of Biological Chemistry 283 (30), 20813-20820, 2008 | 76 | 2008 |
Dyadic plasticity in cardiomyocytes PP Jones, N MacQuaide, WE Louch Frontiers in physiology 9, 1773, 2018 | 68 | 2018 |
Localization of the dantrolene-binding sequence near the FK506-binding protein-binding site in the three-dimensional structure of the ryanodine receptor R Wang, X Zhong, X Meng, A Koop, X Tian, PP Jones, BR Fruen, ... Journal of Biological Chemistry 286 (14), 12202-12212, 2011 | 63 | 2011 |
Impaired relaxation despite upregulated calcium-handling protein atrial myocardium from type 2 diabetic patients with preserved ejection fraction RR Lamberts, SJ Lingam, HY Wang, IAE Bollen, G Hughes, IF Galvin, ... Cardiovascular diabetology 13, 1-12, 2014 | 60 | 2014 |
Relationship between epicardial adipose tissue thickness and epicardial adipocyte size with increasing body mass index HM Aitken-Buck, M Moharram, AA Babakr, R Reijers, I Van Hout, ... Adipocyte 8 (1), 412-420, 2019 | 57 | 2019 |
Localization of PKA phosphorylation site, Ser2030, in the three-dimensional structure of cardiac ryanodine receptor PP Jones, X Meng, B Xiao, S Cai, J Bolstad, T Wagenknecht, Z Liu, ... Biochemical Journal 410 (2), 261-270, 2008 | 57 | 2008 |
Inhibition of calcium/calmodulin-dependent kinase II restores contraction and relaxation in isolated cardiac muscle from type 2 diabetic rats LJ Daniels, RS Wallace, OM Nicholson, GA Wilson, FJ McDonald, ... Cardiovascular diabetology 17, 1-15, 2018 | 51 | 2018 |
Increased efferent cardiac sympathetic nerve activity and defective intrinsic heart rate regulation in type 2 diabetes HPA Thaung, JC Baldi, HY Wang, G Hughes, RF Cook, CT Bussey, ... Diabetes 64 (8), 2944-2956, 2015 | 48 | 2015 |
Characterization of a novel mutation in the cardiac ryanodine receptor that results in catecholaminergic polymorphic ventricular tachycardia D Jiang, PP Jones, D Davis, R Gow, M Green, D Birnie, SRW Chen, ... Channels 4 (4), 302-310, 2010 | 43 | 2010 |