Human haematopoietic stem cell lineage commitment is a continuous process L Velten, SF Haas, S Raffel, S Blaszkiewicz, S Islam, BP Hennig, C Hirche, ... Nature cell biology 19 (4), 271-281, 2017 | 955 | 2017 |
Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization C Baccin, J Al-Sabah, L Velten, PM Helbling, F Grünschläger, ... Nature cell biology 22 (1), 38-48, 2020 | 631 | 2020 |
Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors S Haas, J Hansson, D Klimmeck, D Loeffler, L Velten, H Uckelmann, ... Cell stem cell 17 (4), 422-434, 2015 | 441 | 2015 |
Deciphering the rules by which 5′-UTR sequences affect protein expression in yeast S Dvir, L Velten, E Sharon, D Zeevi, LB Carey, A Weinberger, E Segal Proceedings of the National Academy of Sciences 110 (30), E2792-E2801, 2013 | 297 | 2013 |
Targeted Perturb-seq enables genome-scale genetic screens in single cells D Schraivogel, AR Gschwind, JH Milbank, DR Leonce, P Jakob, L Mathur, ... Nature methods 17 (6), 629-635, 2020 | 169 | 2020 |
Large-scale low-cost NGS library preparation using a robust Tn5 purification and tagmentation protocol BP Hennig, L Velten, I Racke, CS Tu, M Thoms, V Rybin, H Besir, ... G3: Genes, Genomes, Genetics 8 (1), 79-89, 2018 | 144 | 2018 |
Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states S Triana, D Vonficht, L Jopp-Saile, S Raffel, R Lutz, D Leonce, M Antes, ... Nature immunology 22 (12), 1577-1589, 2021 | 110 | 2021 |
Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging K Young, E Eudy, R Bell, MA Loberg, T Stearns, D Sharma, L Velten, ... Cell stem cell 28 (8), 1473-1482. e7, 2021 | 110 | 2021 |
Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics L Velten, BA Story, P Hernández-Malmierca, S Raffel, DR Leonce, ... Nature communications 12 (1), 1366, 2021 | 98 | 2021 |
Single‐cell polyadenylation site mapping reveals 3′ isoform choice variability L Velten, S Anders, A Pekowska, AI Järvelin, W Huber, V Pelechano, ... Molecular systems biology 11 (6), 812, 2015 | 69 | 2015 |
Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia S Beneyto-Calabuig, AK Merbach, JA Kniffka, M Antes, C Szu-Tu, ... Cell Stem Cell, 2023 | 29 | 2023 |
Decoding gene regulation in the mouse embryo using single-cell multi-omics R Argelaguet, T Lohoff, JG Li, A Nakhuda, D Drage, F Krueger, L Velten, ... BioRxiv, 2022.06. 15.496239, 2022 | 27 | 2022 |
scTAM-seq enables targeted high-confidence analysis of DNA methylation in single cells A Bianchi, M Scherer, R Zaurin, K Quililan, L Velten, R Beekman Genome Biology 23 (1), 229, 2022 | 19 | 2022 |
Transcriptomic diversity in human medullary thymic epithelial cells JA Carter, L Strömich, M Peacey, SR Chapin, L Velten, LM Steinmetz, ... Nature Communications 13 (1), 4296, 2022 | 19 | 2022 |
Single‐cell RNA sequencing of motoneurons identifies regulators of synaptic wiring in Drosophila embryos J Velten, X Gao, P Van Nierop y Sanchez, K Domsch, R Agarwal, ... Molecular Systems Biology 18 (3), e10255, 2022 | 8* | 2022 |
Disruption of stem cell niche–confined R-spondin 3 expression leads to impaired hematopoiesis AV Kurtova, M Heinlein, S Haas, L Velten, GJP Dijkgraaf, EE Storm, ... Blood Advances 7 (4), 491-507, 2023 | 5 | 2023 |
Integrative single‐cell expression and functional studies unravels a sensitization to cytarabine‐based chemotherapy through HIF pathway inhibition in AML leukemia stem cells T Velasco‐Hernandez, JL Trincado, M Vinyoles, A Closa, ... HemaSphere 8 (2), e45, 2024 | 1 | 2024 |
Single-cell division tracing and transcriptomics reveal cell types and differentiation paths in the regenerating lung LR Martins, L Sieverling, M Michelhans, C Schiller, C Erkut, ... Nature Communications 15 (1), 2246, 2024 | | 2024 |
Biological basis of extensive pleiotropy between blood traits and cancer risk MA Pardo-Cea, X Farré, A Esteve, J Palade, R Espín, F Mateo, E Alsop, ... Genome Medicine 16 (1), 21, 2024 | | 2024 |
Emergence of activation or repression in transcriptional control under a fixed molecular context R Martinez-Corral, D Friedrich, R Fromel, L Velten, J Gunawardena, ... bioRxiv, 2024.05. 29.596388, 2024 | | 2024 |