Skin tissue generation by laser cell printing L Koch, A Deiwick, S Schlie, S Michael, M Gruene, V Coger, D Zychlinski, ... Biotechnology and bioengineering 109 (7), 1855-1863, 2012 | 672 | 2012 |
Gene therapy for Wiskott-Aldrich syndrome—long-term efficacy and genotoxicity CJ Braun, K Boztug, A Paruzynski, M Witzel, A Schwarzer, M Rothe, ... Science translational medicine 6 (227), 227ra33-227ra33, 2014 | 641 | 2014 |
Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors U Modlich, S Navarro, D Zychlinski, T Maetzig, S Knoess, MH Brugman, ... Molecular Therapy 17 (11), 1919-1928, 2009 | 473 | 2009 |
A modified γ-retrovirus vector for X-linked severe combined immunodeficiency S Hacein-Bey-Abina, SY Pai, HB Gaspar, M Armant, CC Berry, S Blanche, ... New England Journal of Medicine 371 (15), 1407-1417, 2014 | 465 | 2014 |
Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity U Modlich, J Bohne, M Schmidt, C Von Kalle, S Knöss, A Schambach, ... Blood 108 (8), 2545-2553, 2006 | 404 | 2006 |
Long noncoding RNA Chast promotes cardiac remodeling J Viereck, R Kumarswamy, A Foinquinos, K Xiao, P Avramopoulos, ... Science translational medicine 8 (326), 326ra22-326ra22, 2016 | 385 | 2016 |
A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage J Wang, Q Sun, Y Morita, H Jiang, A Groß, A Lechel, K Hildner, ... Cell 148 (5), 1001-1014, 2012 | 381 | 2012 |
Physiological promoters reduce the genotoxic risk of integrating gene vectors D Zychlinski, A Schambach, U Modlich, T Maetzig, J Meyer, E Grassman, ... Molecular Therapy 16 (4), 718-725, 2008 | 367 | 2008 |
Gene therapy on the move KB Kaufmann, H Büning, A Galy, A Schambach, M Grez EMBO molecular medicine 5 (11), 1642-1661, 2013 | 361 | 2013 |
The phenotype of human STK4 deficiency H Abdollahpour, G Appaswamy, D Kotlarz, J Diestelhorst, R Beier, ... Blood, The Journal of the American Society of Hematology 119 (15), 3450-3457, 2012 | 348 | 2012 |
Lentiviral vector design and imaging approaches to visualize the early stages of cellular reprogramming E Warlich, J Kuehle, T Cantz, MH Brugman, T Maetzig, M Galla, ... Molecular Therapy 19 (4), 782-789, 2011 | 324 | 2011 |
Advantages and applications of CAR-expressing natural killer cells W Glienke, R Esser, C Priesner, JD Suerth, A Schambach, WS Wels, ... Frontiers in pharmacology 6, 21, 2015 | 281 | 2015 |
Refined sgRNA efficacy prediction improves large-and small-scale CRISPR–Cas9 applications M Labuhn, FF Adams, M Ng, S Knoess, A Schambach, EM Charpentier, ... Nucleic acids research 46 (3), 1375-1385, 2018 | 271 | 2018 |
Gene insertion into genomic safe harbors for human gene therapy EP Papapetrou, A Schambach Molecular Therapy 24 (4), 678-684, 2016 | 265 | 2016 |
NAMPT is essential for the G-CSF–induced myeloid differentiation via a NAD+–sirtuin-1–dependent pathway J Skokowa, D Lan, BK Thakur, F Wang, K Gupta, G Cario, AM Brechlin, ... Nature medicine 15 (2), 151-158, 2009 | 259 | 2009 |
Context dependence of different modules for posttranscriptional enhancement of gene expression from retroviral vectors A Schambach, H Wodrich, M Hildinger, J Bohne, HG Kräusslich, C Baum Molecular therapy 2 (5), 435-445, 2000 | 248 | 2000 |
Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors M Ehrlich, S Mozafari, M Glatza, L Starost, S Velychko, AL Hallmann, ... Proceedings of the National Academy of Sciences 114 (11), E2243-E2252, 2017 | 242 | 2017 |
Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome D Kotlarz, N Ziętara, G Uzel, T Weidemann, CJ Braun, J Diestelhorst, ... Journal of Experimental Medicine 210 (3), 433-443, 2013 | 238 | 2013 |
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia J Skokowa, G Cario, M Uenalan, A Schambach, M Germeshausen, ... Nature medicine 12 (10), 1191-1197, 2006 | 237 | 2006 |
Large-scale hematopoietic differentiation of human induced pluripotent stem cells provides granulocytes or macrophages for cell replacement therapies N Lachmann, M Ackermann, E Frenzel, S Liebhaber, S Brennig, C Happle, ... Stem cell reports 4 (2), 282-296, 2015 | 231 | 2015 |