Nanomedicine (s) under the microscope R Duncan, R Gaspar Molecular pharmaceutics 8 (6), 2101-2141, 2011 | 1184 | 2011 |
Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity C Fonseca, S Simoes, R Gaspar Journal of controlled release 83 (2), 273-286, 2002 | 934 | 2002 |
SARS-CoV-2 variants and vaccines PR Krause, TR Fleming, IM Longini, R Peto, S Briand, DL Heymann, ... New England Journal of Medicine 385 (2), 179-186, 2021 | 392 | 2021 |
Considerations in boosting COVID-19 vaccine immune responses PR Krause, TR Fleming, R Peto, IM Longini, JP Figueroa, JAC Sterne, ... The Lancet 398 (10308), 1377-1380, 2021 | 359 | 2021 |
Regulatory aspects on nanomedicines V Sainz, J Conniot, AI Matos, C Peres, E Zupanǒiǒ, L Moura, LC Silva, ... Biochemical and biophysical research communications 468 (3), 504-510, 2015 | 332 | 2015 |
Polymeric carriers: preclinical safety and the regulatory implications for design and development of polymer therapeutics R Gaspar, R Duncan Advanced drug delivery reviews 61 (13), 1220-1231, 2009 | 318 | 2009 |
Immune system targeting by biodegradable nanoparticles for cancer vaccines JM Silva, M Videira, R Gaspar, V Préat, HF Florindo Journal of controlled release 168 (2), 179-199, 2013 | 277 | 2013 |
Gene delivery by negatively charged ternary complexes of DNA, cationic liposomes and transferrin or fusigenic peptides S Simões, V Slepushkin, R Gaspar, MC Pedroso de Lima, N Düzgüneş Gene therapy 5 (7), 955-964, 1998 | 254 | 1998 |
Cancer immunotherapy: nanodelivery approaches for immune cell targeting and tracking J Conniot, JM Silva, JG Fernandes, LC Silva, R Gaspar, S Brocchini, ... Frontiers in chemistry 2, 105, 2014 | 231 | 2014 |
Use of the post-insertion technique to insert peptide ligands into pre-formed stealth liposomes with retention of binding activity and cytotoxicity JN Moreira, T Ishida, R Gaspar, TM Allen Pharmaceutical research 19, 265-269, 2002 | 212 | 2002 |
Mechanisms of gene transfer mediated by lipoplexes associated with targeting ligands or pH-sensitive peptides S Simões, V Slepushkin, P Pires, R Gaspar, MC De Lima, N Düzgüneş Gene Therapy 6 (11), 1798-1807, 1999 | 211 | 1999 |
Mesenchymal stem cells promote mammosphere formation and decrease E-cadherin in normal and malignant breast cells AH Klopp, L Lacerda, A Gupta, BG Debeb, T Solley, L Li, E Spaeth, W Xu, ... PloS one 5 (8), e12180, 2010 | 205 | 2010 |
Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serum S Simões, V Slepushkin, P Pires, R Gaspar, MCP De Lima, N Düzgüneş Biochimica et Biophysica Acta (BBA)-Biomembranes 1463 (2), 459-469, 2000 | 196 | 2000 |
Steric stabilization of nanoparticles: size and surface properties C Lourenco, M Teixeira, S Simões, R Gaspar International journal of pharmaceutics 138 (1), 1-12, 1996 | 192 | 1996 |
Interaction of cationic liposomes and their DNA complexes with monocytic leukemia cells P Pires, S Simões, S Nir, R Gaspar, N Düzgünes, MCP de Lima Biochimica et Biophysica Acta (BBA)-Biomembranes 1418 (1), 71-84, 1999 | 177 | 1999 |
How to regulate nonbiological complex drugs (NBCD) and their follow-on versions: points to consider H Schellekens, S Stegemann, V Weinstein, JSB de Vlieger, B Flühmann, ... The AAPS journal 16, 15-21, 2014 | 137 | 2014 |
Poly (lactic acid)-based particulate systems are promising tools for immune modulation C Peres, AI Matos, J Conniot, V Sainz, E Zupančič, JM Silva, L Graca, ... Acta biomaterialia 48, 41-57, 2017 | 131 | 2017 |
Targeting Stealth liposomes in a murine model of human small cell lung cancer JN Moreira, R Gaspar, TM Allen Biochimica et Biophysica Acta (BBA)-Biomembranes 1515 (2), 167-176, 2001 | 123 | 2001 |
Gene delivery mediated by cationic liposomes: from biophysical aspects to enhancement of transfection MC Pedroso, S Simoes, P Pires, R Gaspar, V Slepushkin, N Duzgunes Molecular membrane biology 16 (1), 103-109, 1999 | 119 | 1999 |
Transfection of human macrophages by lipoplexes via the combined use of transferrin and pH-sensitive peptides S Simões, V Slepushkin, E Pretzer, P Dazin, R Gaspar, MCP de Lima, ... Journal of leukocyte biology 65 (2), 270-279, 1999 | 116 | 1999 |