Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes MTE Maghraby, OMF Abou-Ghadir, SG Abdel-Moty, AY Ali, OIA Salem Bioorganic & medicinal chemistry 28 (7), 115403, 2020 | 90 | 2020 |
Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino [1, 2-a] indol-1 (2H)-ones as potential anticancer … BGM Youssif, MH Abdelrahman, AH Abdelazeem, HM Ibrahim, OIA Salem, ... European Journal of Medicinal Chemistry 146, 260-273, 2018 | 68 | 2018 |
Design and synthesis of novel 2, 3-dihydropyrazino [1, 2-a] indole-1, 4-dione derivatives as antiproliferative EGFR and BRAFV600E dual inhibitors LH Al-Wahaibi, AM Gouda, OF Abou-Ghadir, OIA Salem, AT Ali, ... Bioorganic Chemistry 104, 104260, 2020 | 55 | 2020 |
Design and synthesis of some new theophylline derivatives with bronchodilator and antibacterial activities AM Hayallah, WA Elgaher, OI Salem, AAM Abdel Alim Archives of pharmacal research 34, 3-21, 2011 | 50 | 2011 |
Novel 1, 2, 4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity HAM Gomaa, HAM El-Sherief, S Hussein, AM Gouda, OIA Salem, ... Bioorganic chemistry 105, 104369, 2020 | 37 | 2020 |
Novel 5α-reductase inhibitors: synthesis, structure− activity studies, and pharmacokinetic profile of phenoxybenzoylphenyl acetic acids OIA Salem, M Frotscher, C Scherer, A Neugebauer, K Biemel, M Streiber, ... Journal of medicinal chemistry 49 (2), 748-759, 2006 | 35 | 2006 |
New 1, 3, 4‐oxadiazoles linked with the 1, 2, 3‐triazole moiety as antiproliferative agents targeting the EGFR tyrosine kinase MA Mahmoud, AF Mohammed, OIA Salem, HAM Gomaa, BGM Youssif Archiv der Pharmazie 355 (6), 2200009, 2022 | 28 | 2022 |
Development of a hypoxia-selective near-infrared fluorescent probe for non-invasive tumor imaging BGM Youssif, K Okuda, T Kadonosono, OIAR Salem, AAM Hayallah, ... Chemical and Pharmaceutical Bulletin 60 (3), 402-407, 2012 | 27 | 2012 |
Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study MKS El-Nagar, HHM Abdu-Allah, OIA Salem, AHN Kafafy, HSM Farghaly Bioorganic Chemistry 78, 80-93, 2018 | 20 | 2018 |
6-Substituted 3, 4-dihydro-naphthalene-2-carboxylic acids: synthesis and structure-activity studies in a novel class of human 5α reductase inhibitors E Baston, OIA Salem, RW Hartmann Journal of enzyme inhibition and medicinal chemistry 17 (5), 303-320, 2002 | 19 | 2002 |
Synthesis and biological evaluation of 4‐(4‐(alkyl‐and phenylaminocarbonyl) benzoyl) benzoic acid derivatives as non‐steroidal inhibitors of steroid 5α‐reductase isozymes 1 and 2 OIA Salem, T Schulz, RW Hartmann Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 2002 | 17 | 2002 |
Synthesis, anti-bronchoconstrictive, and antibacterial activities of some new 8-substituted-1, 3-dimethylxanthine derivatives WA Elgaher, AM Hayallah, OIA Salem, AAM Abdel Alim Bulletin of Pharmaceutical Sciences Assiut University 32 (1), 153-187, 2009 | 15 | 2009 |
Cyclohex‐1‐ene Carboxylic Acids: Synthesis and Biological Evaluation of Novel Inhibitors of Human 5α Reductase E Baston, OIA Salem, RW Hartmann Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 2003 | 14 | 2003 |
Design, synthesis, and antiproliferative properties of new 1, 2, 3-triazole-carboximidamide derivatives as dual EGFR/VEGFR-2 inhibitors MA Mahmoud, AF Mohammed, OIA Salem, SM Rabea, BGM Youssif Journal of Molecular Structure 1282, 135165, 2023 | 12 | 2023 |
Novel fluoroquinolone hybrids as dual DNA gyrase and urease inhibitors with potential antibacterial activity: design, synthesis, and biological evaluation SA Abdel-Aziz, K Cirnski, J Herrmann, MAA Abdel-Aal, BGM Youssif, ... Journal of Molecular Structure 1271, 134049, 2023 | 10 | 2023 |
New pyrimidine/thiazole hybrids endowed with analgesic, anti‐inflammatory, and lower cardiotoxic activities: Design, synthesis, and COX‐2/sEH dual inhibition SA Abdel‐Aziz, ES Taher, P Lan, NA El‐Koussi, OIA Salem, HAM Gomaa, ... Archiv der Pharmazie 355 (7), 2200024, 2022 | 10 | 2022 |
Synthesis and antimicrobial evaluation of some new thiazoline and thiazolidinone derivatives incorporating [1, 2, 4] triazolo [1, 5-a] benzimidazole AM Mahmoud, OIA Salem, SGA Moty, AMA Alim Indian Journal of Pharmaceutical Sciences 75 (5), 545, 2013 | 7 | 2013 |
Design, synthesis, and modelling study of new 1, 2, 3‐triazole/chalcone hybrids with antiproliferative action as epidermal growth factor receptor inhibitors MTE Maghraby, OIA Salem, BGM Youssif, MM Sheha Chemical Biology & Drug Design 101 (3), 749-759, 2023 | 5 | 2023 |
1, 3, 4-oxadiazoles linked with the 1, 2, 3-triazole moiety as antiproliferative agents targeting the EGFR tyrosine kinase., 2022, 355 MA Mahmoud, AF Mohammed, OI Salem, HA Gomaa, BGY New DOI: https://doi. org/10.1002/ardp 202200009, 2200009, 0 | 5 | |
Development of Near-Infrared Fluorescent Probes with Large Stokes Shifts for Non-Invasive Imaging of Tumor Hypoxia K Okuda, BGM Youssif, R Sakai, T Ueno, T Sakai, T Kadonosono, ... Heterocycles 101 (2), 559-579, 2020 | 3 | 2020 |