Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes P Matre, J Velez, R Jacamo, Y Qi, X Su, T Cai, SM Chan, A Lodi, ... Oncotarget 7 (48), 79722, 2016 | 178 | 2016 |
Hypoxia-activated prodrug TH-302 targets hypoxic bone marrow niches in pre-clinical leukemia models J Benito, MS Ramirez, NZ Millward, J Velez, KG Harutyunyan, H Lu, ... Clinical Cancer Research, clincanres. 3378.2015, 2015 | 71 | 2015 |
Mitochondrial uncoupling and the reprograming of intermediary metabolism in leukemia cells J Vélez, N Hail Jr, M Konopleva, Z Zeng, K Kojima, I Samudio, M Andreeff Frontiers in oncology 3, 67, 2013 | 57 | 2013 |
Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport J Velez, R Pan, JTC Lee, L Enciso, M Suarez, JE Duque, D Jaramillo, ... Oncotarget 7 (32), 51435, 2016 | 37 | 2016 |
Platelets promote mitochondrial uncoupling and resistance to apoptosis in leukemia cells: a novel paradigm for the bone marrow microenvironment J Velez, LJ Enciso, M Suarez, M Fiegl, A Grismaldo, C López, A Barreto, ... Cancer Microenvironment 7, 79-90, 2014 | 34 | 2014 |
Assessing metabolic intervention with a glutaminase inhibitor in real-time by hyperpolarized magnetic resonance in acute myeloid leukemia NM Zacharias, N Baran, SS Shanmugavelandy, J Lee, JV Lujan, P Dutta, ... Molecular cancer therapeutics 18 (11), 1937-1946, 2019 | 21 | 2019 |
Efficacy of novel glutaminase inhibitor CB-839 in acute myeloid leukemia P Matre, M Shariati, J Velez, Y Qi, S Konoplev, X Su, CD DiNardo, ... Blood 124 (21), 3763, 2014 | 14 | 2014 |
Ibrutinib reduces obinutuzumab infusion-related reactions in patients with chronic lymphocytic leukemia and is associated with changes in plasma cytokine levels JV Lujan, PA Lengerke-Diaz, C Jacobs, EF Moreno-Cortes, ... Haematologica 105 (1), e22, 2020 | 13 | 2020 |
Metformin as a novel component of metronomic chemotherapeutic use: a hypothesis JE Duque, J Velez, I Samudio, E Lai Journal of Experimental & Clinical Medicine 4 (3), 140-144, 2012 | 9 | 2012 |
Tratamiento de rescate de leucemia aguda refractaria o en recaída con el régimen IDA-FLAG: experiencia en la rutina de los servicios LJ Enciso, JA Carreño, ML Suárez, CD Bermúdez, M Arango, I Samudio, ... Revista Colombiana de Cancerología 18 (2), 53-61, 2014 | 7 | 2014 |
Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport. Oncotarget. 2016; 7: 51435–49 J Velez, R Pan, JT Lee, L Enciso, M Suarez, JE Duque, D Jaramillo, ... | 5 | |
Obinutuzumab (Gazyva) and high-dose methylprednisolone (HDMP) combination for patients with chronic lymphocytic leukemia (CLL)-a phase Ib/II study JE Castro, CI Amaya-Chanaga, JV Lujan, M Choi, C McCarthy, TJ Kipps Blood 130, 1730, 2017 | 4 | 2017 |
Ibrutinib plus Obinutuzumab as frontline therapy for chronic lymphocytic leukemia is associated with a lower rate of infusion‐related reactions and with sustained remissions … JE Castro, PA Lengerke-Diaz, J Velez Lujan, MY Choi, EF Moreno-Cortes, ... Advances in Hematology 2022 (1), 4450824, 2022 | 3 | 2022 |
Long-Term Sustained Responses Following Ibrutinib Discontinuation after Frontline Therapy with Obinutuzumab Plus Ibrutinib in Patients with Chronic Lymphocytic Leukemia PAL Diaz, MY Choi, EFM Cortes, JV Forero, J Velez-Lujan, ... Blood 136, 33-34, 2020 | 2 | 2020 |
Preclinical evaluation of anti-ROR1 CAR T cells employing a ROR1 binding SCFV derived from the clinical stage mab cirmtuzumab CE Prussak, C Oh, JV Lujan, S Lam, J Zhang, J Fernandez, N Sinha, ... J. Clin. Oncol 38 (41), 10.1200, 2020 | 2 | 2020 |
IACS-010759 is a novel clinical candidate that targets AML cells by inducing a metabolic catastrophe through inhibition of oxidative phosphorylation JR Molina, M Protopopova, M Bandi, J Bardenhagen, C Bristow, C Carroll, ... Cancer Research 76 (14_Supplement), 335-335, 2016 | 2 | 2016 |
Novel Nanomolar Potency Mitochondrial Complex I Inhibitor Iacs-1131 Selectively Kills Oxphos-Dependent AML Cells P Matre, M Protopopova, N Feng, J Gay, J Greer, J Velez, H Mu, A Lodi, ... Blood 124 (21), 622, 2014 | 2 | 2014 |
Ibrutinib Reduces Obinutuzumab-Gazyva Infusion Related Reactions (IRR) in Patients with Chronic Lymphocytic Leukemia (CLL) and It Is Associated with Changes on Plasma Cytokine … JV Lujan, C Jacobs, PAL Diaz, EF Moreno-Cortes, CA Ramirez-Segura, ... Blood 132, 1864, 2018 | 1 | 2018 |
Role of Glutamine in Metabolic and Epigenetic Reprogramming in AML Velez J, Zacharias N, Rakheja D, Bhagat T, Lee J, Dutta P et al Blood 126 (23), 2559, 2015 | 1* | 2015 |
Aberrant spliceosome activity via elevated intron retention and upregulation and phosphorylation of SF3B1 in chronic lymphocytic leukemia MK Kashyap, H Karathia, D Kumar, RV Alvarez, JV Forero-Forero, ... Molecular Therapy-Nucleic Acids 35 (2), 2024 | | 2024 |