| Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity K Hezaveh, RS Shinde, A Klötgen, MJ Halaby, S Lamorte, R Quevedo, ... Immunity 55 (2), 324-340. e8, 2022 | 250 | 2022 |
| Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling SK Loganathan, K Schleicher, A Malik, R Quevedo, E Langille, K Teng, ... Science 367 (6483), 1264-1269, 2020 | 158 | 2020 |
| Revisiting inconsistency in large pharmacogenomic studies Z Safikhani, P Smirnov, M Freeman, N El-Hachem, A She, Q Rene, ... F1000Research 5, 2016 | 117 | 2016 |
| Somatic BRCA1/2 Recovery as a Resistance Mechanism After Exceptional Response to Poly (ADP-ribose) Polymerase Inhibition S Lheureux, JP Bruce, JV Burnier, K Karakasis, PA Shaw, BA Clarke, ... Journal of clinical oncology 35 (11), 1240-1249, 2017 | 93 | 2017 |
| Activating mutations affecting the Dbl homology domain of SOS2 cause Noonan syndrome V Cordeddu, JC Yin, C Gunnarsson, C Virtanen, S Drunat, F Lepri, ... Human mutation 36 (11), 1080-1087, 2015 | 91 | 2015 |
| Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long-and short-term survivors SYC Yang, S Lheureux, K Karakasis, JV Burnier, JP Bruce, DL Clouthier, ... Genome medicine 10, 1-17, 2018 | 83 | 2018 |
| Gene isoforms as expression-based biomarkers predictive of drug response in vitro Z Safikhani, P Smirnov, KL Thu, J Silvester, N El-Hachem, R Quevedo, ... Nature communications 8 (1), 1126, 2017 | 71 | 2017 |
| The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity S Lukhele, D Abd Rabbo, M Guo, J Shen, HJ Elsaesser, R Quevedo, ... Immunity 55 (12), 2369-2385. e10, 2022 | 44 | 2022 |
| Assessment of pharmacogenomic agreement Z Safikhani, N El-Hachem, R Quevedo, P Smirnov, A Goldenberg, ... F1000Research 5, 2016 | 38 | 2016 |
| Pre-encoded responsiveness to type I interferon in the peripheral immune system defines outcome of PD1 blockade therapy GM Boukhaled, R Gadalla, HJ Elsaesser, D Abd-Rabbo, R Quevedo, ... Nature immunology 23 (8), 1273-1283, 2022 | 28 | 2022 |
| Assessment of genetic drift in large pharmacogenomic studies R Quevedo, P Smirnov, D Tkachuk, C Ho, N El-Hachem, Z Safikhani, ... Cell systems 11 (4), 393-401. e2, 2020 | 22 | 2020 |
| Chronic cochlear implantation with and without electric stimulation in a mouse model induces robust cochlear influx of CX3CR1+/GFP macrophages AD Claussen, RV Quevedo, JR Kirk, T Higgins, B Mostaert, MT Rahman, ... Hearing research 426, 108510, 2022 | 15 | 2022 |
| An integrative DNA sequencing and methylation panel to assess mismatch repair deficiency LE Oldfield, T Li, A Tone, M Aronson, M Edwards, S Holter, R Quevedo, ... The Journal of Molecular Diagnostics 23 (2), 242-252, 2021 | 13 | 2021 |
| Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor R Quevedo, A Spreafico, J Bruce, A Danesh, S El Ghamrasni, A Giesler, ... Genome Medicine 12, 1-15, 2020 | 13 | 2020 |
| Heterogeneous alteration of the ERBB3–MYC axis associated with MEK inhibitor resistance in a KRAS-mutated low-grade serous ovarian cancer patient I Colombo, S Garg, A Danesh, J Bruce, P Shaw, Q Tan, R Quevedo, ... Molecular Case Studies 5 (6), a004341, 2019 | 8 | 2019 |
| KSR1 knockout mouse model demonstrates MAPK pathway’s key role in cisplatin-and noise-induced hearing loss MA Ingersoll, RD Lutze, RG Kelmann, DF Kresock, JD Marsh, ... Journal of Neuroscience 44 (18), 2024 | 4 | 2024 |
| Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer S El Ghamrasni, R Quevedo, J Hawley, P Mazrooei, Y Hanna, I Cirlan, ... Molecular Cancer Research 20 (1), 102-113, 2022 | 3 | 2022 |
| EHMT2/G9a-Inhibition reprograms cancer-associated fibroblasts (CAFs) to a more differentiated, less proliferative and invasive state NC Wu, R Quevedo, M Nurse, K Hezaveh, H Liu, F Sun, J Muffat, Y Sun, ... bioRxiv, 2023.07. 17.549300, 2023 | 1 | 2023 |
| Author Correction: Gene isoforms as expression-based biomarkers predictive of drug response in vitro Z Safikhani, P Smirnov, KL Thu, J Silvester, N El-Hachem, R Quevedo, ... Nature communications 9 (1), 166, 2018 | 1 | 2018 |
| In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss S Vijayakumar, JA DiGuiseppi, PJ Dabestani, WG Ryan, RV Quevedo, ... Science Advances 10 (25), eadk2299, 2024 | | 2024 |
