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Leonardo Giovannoni
Leonardo Giovannoni
GSK Vaccines
在 gsk.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Immunoscintigraphic detection of the ED-B domain of fibronectin, a marker of angiogenesis, in patients with cancer
M Santimaria, G Moscatelli, GL Viale, L Giovannoni, G Neri, F Viti, ...
Clinical Cancer Research 9 (2), 571-579, 2003
3972003
Increased binding affinity and valence of recombinant antibody fragments lead to improved targeting of tumoral angiogenesis
F Viti, L Tarli, L Giovannoni, L Zardi, D Neri
Cancer research 59 (2), 347-352, 1999
3131999
The tumour-targeting human L19-IL2 immunocytokine: preclinical safety studies, phase I clinical trial in patients with solid tumours and expansion into patients with advanced …
M Johannsen, G Spitaleri, G Curigliano, J Roigas, S Weikert, ...
European journal of cancer 46 (16), 2926-2935, 2010
1992010
Expression of the oncofetal ED-B–containing fibronectin isoform in hematologic tumors enables ED-B–targeted 131I-L19SIP radioimmunotherapy in Hodgkin …
S Sauer, PA Erba, M Petrini, A Menrad, L Giovannoni, C Grana, B Hirsch, ...
Blood, The Journal of the American Society of Hematology 113 (10), 2265-2274, 2009
1972009
A dose-escalation and signal-generating study of the immunocytokine L19-IL2 in combination with dacarbazine for the therapy of patients with metastatic melanoma
TK Eigentler, B Weide, F de Braud, G Spitaleri, A Romanini, A Pflugfelder, ...
Clinical Cancer Research 17 (24), 7732-7742, 2011
1782011
A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage
S Demartis, A Huber, F Viti, L Lozzi, L Giovannoni, P Neri, G Winter, ...
Journal of molecular biology 286 (2), 617-633, 1999
1711999
Intralesional administration of L19-IL2/L19-TNF in stage III or stage IVM1a melanoma patients: results of a phase II study
R Danielli, R Patuzzo, AM Di Giacomo, G Gallino, A Maurichi, A Di Florio, ...
Cancer immunology, immunotherapy 64, 999-1009, 2015
1662015
Antibody-mediated delivery of interleukin-2 to the stroma of breast cancer strongly enhances the potency of chemotherapy
J Marlind, M Kaspar, E Trachsel, R Sommavilla, S Hindle, C Bacci, ...
Clinical Cancer Research 14 (20), 6515-6524, 2008
1462008
Antibody-based delivery of interleukin-2 to neovasculature has potent activity against acute myeloid leukemia
KL Gutbrodt, C Schliemann, L Giovannoni, K Frey, T Pabst, W Klapper, ...
Science translational medicine 5 (201), 201ra118-201ra118, 2013
1322013
Phase I/II study of the tumour-targeting human monoclonal antibody–cytokine fusion protein L19-TNF in patients with advanced solid tumours
G Spitaleri, R Berardi, C Pierantoni, T De Pas, C Noberasco, C Libbra, ...
Journal of cancer research and clinical oncology 139, 447-455, 2013
1142013
Isolated limb perfusion with the tumor‐targeting human monoclonal antibody–cytokine fusion protein L19‐TNF plus melphalan and mild hyperthermia in patients with locally …
F Papadia, V Basso, R Patuzzo, A Maurichi, A Di Florio, L Zardi, E Ventura, ...
Journal of surgical oncology 107 (2), 173-179, 2013
1122013
The antibody-based targeted delivery of TNF in combination with doxorubicin eradicates sarcomas in mice and confers protective immunity
T Hemmerle, P Probst, L Giovannoni, AJ Green, T Meyer, D Neri
British journal of cancer 109 (5), 1206-1213, 2013
1012013
Intralesional treatment of stage III metastatic melanoma patients with L19–IL2 results in sustained clinical and systemic immunologic responses
B Weide, TK Eigentler, A Pflugfelder, H Zelba, A Martens, G Pawelec, ...
Cancer immunology research 2 (7), 668-678, 2014
94*2014
Radretumab Radioimmunotherapy in Patients with Brain Metastasis: A 124I-L19SIP Dosimetric PET Study
GL Poli, C Bianchi, G Virotta, A Bettini, R Moretti, E Trachsel, G Elia, ...
Cancer immunology research 1 (2), 134-143, 2013
852013
Isolation of anti-angiogenesis antibodies from a large combinatorial repertoire by colony filter screening
L Giovannoni, F Viti, L Zardi, D Neri
Nucleic Acids Research 29 (5), e27-e27, 2001
812001
Radioimmunotherapy with radretumab in patients with relapsed hematologic malignancies
PA Erba, M Sollini, E Orciuolo, C Traino, M Petrini, G Paganelli, ...
Journal of nuclear medicine 53 (6), 922-927, 2012
752012
Phase 0 microdosing PET study using the human mini antibody F16SIP in head and neck cancer patients
DA Heuveling, R de Bree, DJ Vugts, MC Huisman, L Giovannoni, ...
Journal of Nuclear Medicine 54 (3), 397-401, 2013
602013
The tumor-targeting immunocytokine F16-IL2 in combination with doxorubicin: dose escalation in patients with advanced solid tumors and expansion into patients with metastatic …
C Catania, M Maur, R Berardi, A Rocca, AMD Giacomo, G Spitaleri, ...
Cell adhesion & migration 9 (1-2), 14-21, 2015
592015
A phase IB clinical trial with Dekavil (F8-IL10), an immunoregulatory ‘armed antibody’for the treatment of rheumatoid arthritis, used in combination wiIh methotrexate
M Galeazzi, L Bazzichi, GD Sebastiani, D Neri, E Garcia, N Ravenni, ...
Isr Med Assoc J 16 (10), 666, 2014
542014
Targeting interleukin-2 to the bone marrow stroma for therapy of acute myeloid leukemia relapsing after allogeneic hematopoietic stem cell transplantation
C Schliemann, KL Gutbrodt, A Kerkhoff, M Pohlen, S Wiebe, G Silling, ...
Cancer immunology research 3 (5), 547-556, 2015
522015
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