95 kd sperm proteins bind ZP3 and serve as tyrosine kinase substrates in response to zona binding L Leyton, P Saling Cell 57 (7), 1123-1130, 1989 | 441 | 1989 |
Evidence that aggregation of mouse sperm receptors by ZP3 triggers the acrosome reaction. L Leyton, P Saling The Journal of Cell Biology 108 (6), 2163-2168, 1989 | 276 | 1989 |
Caveolins, caveolae, and lipid rafts in cellular transport, signaling, and disease AFG Quest, L Leyton, M Párraga Biochemistry and cell biology 82 (1), 129-144, 2004 | 273 | 2004 |
Regulation of mouse gamete interaction by a sperm tyrosine kinase L Leyton, P LeGuen, D Bunch, PM Saling Proceedings of the National Academy of Sciences 89 (24), 11692-11695, 1992 | 186 | 1992 |
Thy-1 binds to integrin β 3 on astrocytes and triggers formation of focal contact sites L Leyton, P Schneider, CV Labra, C Rüegg, CA Hetz, AFG Quest, C Bron Current Biology 11 (13), 1028-1038, 2001 | 176 | 2001 |
Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent transcription JG Fernández, DA Rodríguez, M Valenzuela, C Calderon, U Urzúa, ... Molecular cancer 13 (1), 209, 2014 | 169 | 2014 |
Caspase-dependent initiation of apoptosis and necrosis by the Fas receptor in lymphoid cells: onset of necrosis is associated with delayed ceramide increase CA Hetz, M Hunn, P Rojas, V Torres, L Leyton, AFG Quest Journal of cell science 115 (23), 4671-4683, 2002 | 169 | 2002 |
Casein kinase 2 (CK2) increases survivin expression via enhanced β-catenin–T cell factor/lymphoid enhancer binding factor-dependent transcription JC Tapia, VA Torres, DA Rodriguez, L Leyton, AFG Quest Proceedings of the National Academy of Sciences 103 (41), 15079-15084, 2006 | 167 | 2006 |
Caveolin-1 controls cell proliferation and cell death by suppressing expression of the inhibitor of apoptosis protein survivin VA Torres, JC Tapia, DA Rodríguez, M Párraga, P Lisboa, M Montoya, ... Journal of cell science 119 (9), 1812-1823, 2006 | 149 | 2006 |
E-cadherin is required for caveolin-1-mediated down-regulation of the inhibitor of apoptosis protein survivin via reduced β-catenin-Tcf/Lef-dependent transcription VA Torres, JC Tapia, DA Rodriguez, A Lladser, C Arredondo, L Leyton, ... Molecular and cellular biology 27 (21), 7703-7717, 2007 | 147 | 2007 |
Enhanced degradation of proteins of the basal lamina and stroma by matrix metalloproteinases from the salivary glands of Sjögren's syndrome patients: correlation with reduced … E Goicovich, C Molina, P Pérez, S Aguilera, J Fernández, N Olea, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2003 | 130 | 2003 |
Recombinant mouse ZP3 inhibits sperm binding and induces the acrosome reaction SJ Beebe, L Leyton, D Burks, M Ishikawa, T Fuerst, J Dean, P Saling Developmental biology 151 (1), 48-54, 1992 | 118 | 1992 |
Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells P Mendoza, R Ortiz, J Díaz, AFG Quest, L Leyton, D Stupack, VA Torres J Cell Sci 126 (17), 3835-3847, 2013 | 114 | 2013 |
Rab5 is required in metastatic cancer cells for Caveolin-1-enhanced Rac1 activation, migration and invasion J Díaz, P Mendoza, R Ortiz, N Díaz, L Leyton, D Stupack, AFG Quest, ... J Cell Sci 127 (11), 2401-2406, 2014 | 106 | 2014 |
Aggregation of integrins and RhoA activation are required for Thy-1-induced morphological changes in astrocytes AM Avalos, WT Arthur, P Schneider, AFG Quest, K Burridge, L Leyton Journal of Biological Chemistry 279 (37), 39139-39145, 2004 | 100 | 2004 |
Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with αvβ3 integrin that activates PKCα and RhoA AM Avalos, AD Valdivia, N Muñoz, R Herrera-Molina, JC Tapia, ... Journal of cell science 122 (19), 3462-3471, 2009 | 99 | 2009 |
Increased acinar damage of salivary glands of patients with Sjögren's syndrome is paralleled by simultaneous imbalance of matrix metalloproteinase 3/tissue inhibitor of … P Pérez, YJ Kwon, C Alliende, L Leyton, S Aguilera, C Molina, C Labra, ... Arthritis & Rheumatism 52 (9), 2751-2760, 2005 | 98 | 2005 |
Direct Thy-1/α V β 3 integrin interaction mediates neuron to astrocyte communication T Hermosilla, D Muñoz, R Herrera-Molina, A Valdivia, N Muñoz, SU Nham, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (6), 1111-1120, 2008 | 97 | 2008 |
The caveolin-1 connection to cell death and survival A FG Quest, L Lobos-González, S Nunez, C Sanhueza, JG Fernández, ... Current molecular medicine 13 (2), 266-281, 2013 | 91 | 2013 |
Caveolin-1–mediated Suppression of Cyclooxygenase-2 via a β-catenin-Tcf/Lef–dependent Transcriptional Mechanism Reduced Prostaglandin E2 Production and Survivin Expression DA Rodriguez, JC Tapia, JG Fernandez, VA Torres, N Muñoz, ... Molecular biology of the cell 20 (8), 2297-2310, 2009 | 91 | 2009 |