A model for transmission of the H3K27me3 epigenetic mark KH Hansen, AP Bracken, D Pasini, N Dietrich, SS Gehani, A Monrad, ... Nature cell biology 10 (11), 1291-1300, 2008 | 838 | 2008 |
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition JA Dahl, I Jung, H Aanes, GD Greggains, A Manaf, M Lerdrup, G Li, ... Nature 537 (7621), 548-552, 2016 | 546 | 2016 |
Differential effects of EGFR ligands on endocytic sorting of the receptor K Roepstorff, MV Grandal, L Henriksen, SLJ Knudsen, M Lerdrup, ... Traffic 10 (8), 1115-1127, 2009 | 436 | 2009 |
Endocytic downregulation of ErbB receptors: mechanisms and relevance in cancer K Roepstorff, L Grøvdal, M Grandal, M Lerdrup, B van Deurs Histochemistry and cell biology 129, 563-578, 2008 | 263 | 2008 |
Association with membrane protrusions makes ErbB2 an internalization-resistant receptor AM Hommelgaard, M Lerdrup, B van Deurs Molecular biology of the cell 15 (4), 1557-1567, 2004 | 254 | 2004 |
An interactive environment for agile analysis and visualization of ChIP-sequencing data M Lerdrup, JV Johansen, S Agrawal-Singh, K Hansen Nature structural & molecular biology 23 (4), 349-357, 2016 | 251 | 2016 |
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia S Göllner, T Oellerich, S Agrawal-Singh, T Schenk, HU Klein, C Rohde, ... Nature medicine 23 (1), 69-78, 2017 | 231 | 2017 |
REST–mediated recruitment of Polycomb repressor complexes in mammalian cells N Dietrich, M Lerdrup, E Landt, S Agrawal-Singh, M Bak, N Tommerup, ... PLoS genetics 8 (3), e1002494, 2012 | 197 | 2012 |
β-Catenin regulates primitive streak induction through collaborative interactions with SMAD2/SMAD3 and OCT4 NS Funa, KA Schachter, M Lerdrup, J Ekberg, K Hess, N Dietrich, ... Cell stem cell 16 (6), 639-652, 2015 | 155 | 2015 |
A novel specific role for IκB kinase complex-associated protein in cytosolic stress signaling C Holmberg, S Katz, M Lerdrup, T Herdegen, M Jäättelä, A Aronheim, ... Journal of Biological Chemistry 277 (35), 31918-31928, 2002 | 129 | 2002 |
Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing M Shoaib, D Walter, PJ Gillespie, F Izard, B Fahrenkrog, D Lleres, ... Nature communications 9 (1), 3704, 2018 | 97 | 2018 |
KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes A Sankar, M Lerdrup, A Manaf, JV Johansen, JM Gonzalez, R Borup, ... Nature Cell Biology 22 (4), 380-388, 2020 | 88 | 2020 |
Geldanamycin stimulates internalization of ErbB2 in a proteasome-dependent way M Lerdrup, AM Hommelgaard, M Grandal, B van Deurs Journal of cell science 119 (1), 85-95, 2006 | 86 | 2006 |
Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals A Sankar, F Mohammad, AK Sundaramurthy, H Wang, M Lerdrup, T Tatar, ... Nature genetics 54 (6), 754-760, 2022 | 84 | 2022 |
DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding T Schoofs, C Rohde, K Hebestreit, HU Klein, S Göllner, I Schulze, ... Blood, The Journal of the American Society of Hematology 121 (1), 178-187, 2013 | 82 | 2013 |
JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways N Dietrich, J Thastrup, C Holmberg, M Gyrd-Hansen, N Fehrenbacher, ... Cell Death & Differentiation 11 (3), 301-313, 2004 | 80 | 2004 |
Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes M Shoaib, Q Chen, X Shi, N Nair, C Prasanna, R Yang, D Walter, ... Nature communications 12 (1), 4800, 2021 | 71 | 2021 |
Proteogenomic characterization of patient-derived xenografts highlights the role of REST in neuroendocrine differentiation of castration-resistant prostate cancer A Flores-Morales, TB Bergmann, C Lavallee, TS Batth, D Lin, M Lerdrup, ... Clinical Cancer Research 25 (2), 595-608, 2019 | 67 | 2019 |
Dopamine signaling leads to loss of Polycomb repression and aberrant gene activation in experimental parkinsonism E Södersten, M Feyder, M Lerdrup, AL Gomes, H Kryh, G Spigolon, ... PLoS genetics 10 (9), e1004574, 2014 | 61 | 2014 |
Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus M Lerdrup, S Bruun, MV Grandal, K Roepstorff, MM Kristensen, ... Molecular biology of the cell 18 (9), 3656-3666, 2007 | 61 | 2007 |