| PINK1/PARKIN signalling in neurodegeneration and neuroinflammation. PMJ Quinn, PI Moreira, AF Ambrósio, CH Alves Acta Neuropathol Commun, 2020 | 313 | 2020 |
| Targeted Ablation of Crb1 and Crb2 in Retinal Progenitor Cells Mimics Leber Congenital Amaurosis LP Pellissier, CH Alves, PM Quinn, RM Vos, N Tanimoto, DMS Lundvig, ... PLoS genetics 9 (12), e1003976, 2013 | 96 | 2013 |
| Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5 PM Quinn, TM Buck, AA Mulder, C Ohonin, CH Alves, RM Vos, M Bialecka, ... Stem Cell Reports, 2019 | 94 | 2019 |
| Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models LP Pellissier, PM Quinn, CH Alves, RM Vos, J Klooster, JG Flannery, ... Human molecular genetics 24 (11), 3104-3118, 2015 | 91 | 2015 |
| The CRB1 complex: following the trail of crumbs to a feasible gene therapy strategy PM Quinn, LP Pellissier, J Wijnholds Frontiers in neuroscience 11, 175, 2017 | 65 | 2017 |
| Organoids and organ chips in ophthalmology N Manafi, F Shokri, K Achberger, M Hirayama, MH Mohammadi, ... The Ocular Surface, 2020 | 61 | 2020 |
| Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype PM Quinn, AA Mulder, CH Alves, M Desrosiers, SI de Vries, J Klooster, ... Human Molecular Genetics, 2019 | 49 | 2019 |
| CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and function PM Quinn, CH Alves, J Klooster, J Wijnholds Human Molecular Genetics 27 (18), 2018 | 46 | 2018 |
| Role of Oxidative Stress in Retinal Ganglion Cells degenerations EYC Kang, PK Liu, YT Wen, PMJ Quinn, SR Levi, NK Wang, RK Tsai Antioxidants, 2021 | 45 | 2021 |
| Retinogenesis of the Human Fetal Retina: An Apical Polarity Perspective PMJ Quinn, J Wijnholds Genes, 2019 | 41 | 2019 |
| Production of iPS-derived human retinal organoids for use in transgene expression assays PM Quinn, TM Buck, C Ohonin, HMM Mikkers, J Wijnholds Retinal Gene Therapy: Methods and Protocols, 261-273, 2018 | 29 | 2018 |
| The role of small molecules and their effect on the molecular mechanisms of early retinal organoid development PE Wagstaff, A Heredero Berzal, CJF Boon, PMJ Quinn, A ten Asbroek, ... International Journal of Molecular Sciences, 2021 | 26 | 2021 |
| Prime Editing for Inherited Retinal Diseases BLD Costa, SR Levi, E Eulau, YT Tsai, PMJ Quinn Frontiers In Genome Editing, 2021 | 24 | 2021 |
| CRISPR genome surgery in a novel humanized model for autosomal dominant retinitis pigmentosa WH Wu, YT Tsai, IW Huang, CH Cheng, CW Hsu, X Cui, J Ryu, ... Molecular Therapy, 2022 | 22 | 2022 |
| Phase transition specified by a binary code patterns the vertebrate eye cup R Balasubramanian, X Min, PMJ Quinn, Q Lo Giudice, C Tao, K Polanco, ... Science Advances 7, 2021 | 17 | 2021 |
| CRISPR/Cas therapeutic strategies for autosomal dominant disorders SM Caruso, PMJ Quinn, BLD Costa, SH Tsang The Journal of Clinical Investigation, 2022 | 15 | 2022 |
| Impaired cholesterol efflux in retinal pigment epithelium of individuals with juvenile macular degeneration Y Tsai, Y Li, J Ryu, P Su, C Cheng, W Wu, Y Li, PMJ Quinn, KW Leong, ... The American Journal of Human Genetics, 2021 | 13 | 2021 |
| Defining phenotype, tropism, and retinal gene therapy using adeno-associated viral vectors (AAV) in new-born Brown Norway rats with a spontaneous mutation in Crb1 N Boon, CH Alves, AA Mulder, CA Andriessen, TM Buck, PMJ Quinn, ... International Journal of Molecular Sciences, 2021 | 13 | 2021 |
| Precision metabolome reprogramming for imprecision therapeutics in retinitis pigmentosa S Caruso, J Ryu, PMJ Quinn, SH Tsang The Journal of Clinical Investigation, 2020 | 13 | 2020 |
| HIF2α activation and mitochondrial deficit due to iron chelation cause retinal atrophy Y Kong, PK Liu, Y Li, ND Nolan, PMJ Quinn, CW Hsu, LA Jenny, J Zhao, ... EMBO Molecular Medicine, e16525, 2023 | 10 | 2023 |
C. Henrique AlvesICBR Coimbra Institute for Clinical and Biomedical Research在 fmed.uc.pt 的电子邮件经过验证
