Mechanisms of transcriptional regulation by p53 KD Sullivan, MD Galbraith, Z Andrysik, JM Espinosa Cell Death & Differentiation 25 (1), 133-143, 2018 | 447 | 2018 |
Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms MA Allen, Z Andrysik, VL Dengler, HS Mellert, A Guarnieri, JA Freeman, ... Elife 3, e02200, 2014 | 268 | 2014 |
Trisomy 21 consistently activates the interferon response KD Sullivan, HC Lewis, AA Hill, A Pandey, LP Jackson, JM Cabral, ... Elife 5, e16220, 2016 | 265 | 2016 |
Autophagy inhibition mediates apoptosis sensitization in cancer therapy by relieving FOXO3a turnover BE Fitzwalter, CG Towers, KD Sullivan, Z Andrysik, M Hoh, M Ludwig, ... Developmental cell 44 (5), 555-565. e3, 2018 | 187 | 2018 |
Trisomy 21 causes changes in the circulating proteome indicative of chronic autoinflammation KD Sullivan, D Evans, A Pandey, TH Hraha, KP Smith, N Markham, ... Scientific reports 7 (1), 14818, 2017 | 179 | 2017 |
Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity Z Andrysik, MD Galbraith, AL Guarnieri, S Zaccara, KD Sullivan, A Pandey, ... Genome research 27 (10), 1645-1657, 2017 | 142 | 2017 |
Nuclear autoantigenic sperm protein (NASP), a linker histone chaperone that is required for cell proliferation RT Richardson, OM Alekseev, G Grossman, EE Widgren, R Thresher, ... Journal of Biological Chemistry 281 (30), 21526-21534, 2006 | 139 | 2006 |
A core complex of CPSF73, CPSF100, and Symplekin may form two different cleavage factors for processing of poly (A) and histone mRNAs KD Sullivan, M Steiniger, WF Marzluff Molecular cell 34 (3), 322-332, 2009 | 134 | 2009 |
Therapeutic targeting of MLL degradation pathways in MLL-rearranged leukemia K Liang, AG Volk, JS Haug, SA Marshall, AR Woodfin, ET Bartom, ... Cell 168 (1), 59-72. e13, 2017 | 124 | 2017 |
The p53 circuit board KD Sullivan, CL Gallant-Behm, RE Henry, JL Fraikin, JM Espinosa Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1825 (2), 229-244, 2012 | 122 | 2012 |
Knockdown of SLBP results in nuclear retention of histone mRNA KD Sullivan, TE Mullen, WF Marzluff, EJ Wagner Rna 15 (3), 459-472, 2009 | 106 | 2009 |
Trisomy 21 dysregulates T cell lineages toward an autoimmunity-prone state associated with interferon hyperactivity P Araya, KA Waugh, KD Sullivan, NG Núñez, E Roselli, KP Smith, ... Proceedings of the National Academy of Sciences 116 (48), 24231-24241, 2019 | 103 | 2019 |
Mass cytometry reveals global immune remodeling with multi-lineage hypersensitivity to type I interferon in Down syndrome KA Waugh, P Araya, A Pandey, KR Jordan, KP Smith, RE Granrath, ... Cell reports 29 (7), 1893-1908. e4, 2019 | 98 | 2019 |
CDK8 kinase activity promotes glycolysis MD Galbraith, Z Andrysik, A Pandey, M Hoh, EA Bonner, AA Hill, ... Cell reports 21 (6), 1495-1506, 2017 | 85 | 2017 |
Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors RK Powers, R Culp-Hill, MP Ludwig, KP Smith, KA Waugh, R Minter, ... Nature communications 10 (1), 1-11, 2019 | 84 | 2019 |
ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53 KD Sullivan, N Padilla-Just, RE Henry, CC Porter, J Kim, JJ Tentler, ... Nature chemical biology 8 (7), 646-654, 2012 | 81 | 2012 |
Studies of the 5′ exonuclease and endonuclease activities of CPSF-73 in histone pre-mRNA processing X Yang, KD Sullivan, WF Marzluff, Z Dominski Molecular and cellular biology 29 (1), 31-42, 2009 | 78 | 2009 |
Specialized interferon action in COVID-19 MD Galbraith, KT Kinning, KD Sullivan, P Araya, KP Smith, RE Granrath, ... Proceedings of the National Academy of Sciences 119 (11), e2116730119, 2022 | 77 | 2022 |
Inhibition of telomerase recruitment and cancer cell death M Nakashima, J Nandakumar, KD Sullivan, JM Espinosa, TR Cech Journal of Biological Chemistry 288 (46), 33171-33180, 2013 | 59 | 2013 |
Seroconversion stages COVID19 into distinct pathophysiological states MD Galbraith, KT Kinning, KD Sullivan, R Baxter, P Araya, KR Jordan, ... Elife 10, e65508, 2021 | 50 | 2021 |