Microfibrillar structure of type I collagen in situ JPRO Orgel, TC Irving, A Miller, TJ Wess Proceedings of the National Academy of Sciences 103 (24), 9001-9005, 2006 | 1111 | 2006 |
Passive tension in cardiac muscle: contribution of collagen, titin, microtubules, and intermediate filaments HL Granzier, TC Irving Biophysical journal 68 (3), 1027-1044, 1995 | 734 | 1995 |
X-ray diffraction measurements of the extensibility of actin and myosin filaments in contracting muscle HE Huxley, A Stewart, H Sosa, T Irving Biophysical journal 67 (6), 2411-2421, 1994 | 527 | 1994 |
The in situ supermolecular structure of type I collagen JPRO Orgel, A Miller, TC Irving, RF Fischetti, AP Hammersley, TJ Wess Structure 9 (11), 1061-1069, 2001 | 416 | 2001 |
Skeletal muscle performance determined by modulation of number of myosin motors rather than motor force or stroke size G Piazzesi, M Reconditi, M Linari, L Lucii, P Bianco, E Brunello, ... Cell 131 (4), 784-795, 2007 | 359 | 2007 |
Myofilament length dependent activation PP de Tombe, RD Mateja, K Tachampa, YA Mou, GP Farman, TC Irving Journal of molecular and cellular cardiology 48 (5), 851-858, 2010 | 323 | 2010 |
Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers RL Anderson, DV Trivedi, SS Sarkar, M Henze, W Ma, H Gong, ... Proceedings of the National Academy of Sciences 115 (35), E8143-E8152, 2018 | 306 | 2018 |
Titin-based modulation of calcium sensitivity of active tension in mouse skinned cardiac myocytes O Cazorla, Y Wu, TC Irving, H Granzier Circulation research 88 (10), 1028-1035, 2001 | 286 | 2001 |
The myosin motor in muscle generates a smaller and slower working stroke at higher load M Reconditi, M Linari, L Lucii, A Stewart, YB Sun, P Boesecke, ... Nature 428 (6982), 578-581, 2004 | 229 | 2004 |
Shape of tropoelastin, the highly extensible protein that controls human tissue elasticity C Baldock, AF Oberhauser, L Ma, D Lammie, V Siegler, SM Mithieux, Y Tu, ... Proceedings of the National Academy of Sciences 108 (11), 4322-4327, 2011 | 225 | 2011 |
The role of sugar, vitrification and membrane phase transition in seed desiccation tolerance WQ Sun, TC Irving, AC Leopold Physiologia Plantarum 90 (4), 621-628, 1994 | 203 | 1994 |
Differential roles of regulatory light chain and myosin binding protein‐C phosphorylations in the modulation of cardiac force development BA Colson, MR Locher, T Bekyarova, JR Patel, DP Fitzsimons, TC Irving, ... The Journal of physiology 588 (6), 981-993, 2010 | 196 | 2010 |
Titin strain contributes to the Frank–Starling law of the heart by structural rearrangements of both thin-and thick-filament proteins Y Ait-Mou, K Hsu, GP Farman, M Kumar, ML Greaser, TC Irving, ... Proceedings of the National Academy of Sciences 113 (8), 2306-2311, 2016 | 184 | 2016 |
Troponin I in the murine myocardium: influence on length‐dependent activation and interfilament spacing JP Konhilas, TC Irving, BM Wolska, EE Jweied, AF Martin, RJ Solaro, ... The Journal of physiology 547 (3), 951-961, 2003 | 180 | 2003 |
Myofilament lattice spacing as a function of sarcomere length in isolated rat myocardium TC Irving, J Konhilas, D Perry, R Fischetti, PP De Tombe American Journal of Physiology-Heart and Circulatory Physiology 279 (5 …, 2000 | 179 | 2000 |
The BioCAT undulator beamline 18ID: a facility for biological non-crystalline diffraction and X-ray absorption spectroscopy at the Advanced Photon Source R Fischetti, S Stepanov, G Rosenbaum, R Barrea, E Black, D Gore, ... Journal of synchrotron radiation 11 (5), 399-405, 2004 | 173 | 2004 |
Myofilament calcium sensitivity in skinned rat cardiac trabeculae: role of interfilament spacing JP Konhilas, TC Irving, PP de Tombe Circulation research 90 (1), 59-65, 2002 | 172 | 2002 |
Improved fitting of solution X-ray scattering data to macromolecular structures and structural ensembles by explicit water modeling A Grishaev, L Guo, T Irving, A Bax Journal of the American Chemical Society 132 (44), 15484-15486, 2010 | 149 | 2010 |
Titin isoform variance and length dependence of activation in skinned bovine cardiac muscle N Fukuda, Y Wu, G Farman, TC Irving, H Granzier The Journal of physiology 553 (1), 147-154, 2003 | 146 | 2003 |
Frank-Starling law of the heart and the cellular mechanisms of length-dependent activation. JP Konhilas, TC Irving, PP de Tombe Pflügers Archiv: European journal of physiology 445 (3), 2002 | 145 | 2002 |