The nucleus accumbens: mechanisms of addiction across drug classes reflect the importance of glutamate homeostasis MD Scofield, JA Heinsbroek, CD Gipson, YM Kupchik, S Spencer, ... Pharmacological reviews 68 (3), 816-871, 2016 | 540 | 2016 |
Coding the direct/indirect pathways by D1 and D2 receptors is not valid for accumbens projections YM Kupchik, RM Brown, JA Heinsbroek, MK Lobo, DJ Schwartz, ... Nature neuroscience 18 (9), 1230-1232, 2015 | 489 | 2015 |
Optogenetic inhibition of cocaine seeking in rats MT Stefanik, K Moussawi, YM Kupchik, KC Smith, RL Miller, ML Huff, ... Addiction biology 18 (1), 50-53, 2013 | 287 | 2013 |
Reinstatement of nicotine seeking is mediated by glutamatergic plasticity CD Gipson, KJ Reissner, YM Kupchik, ACW Smith, N Stankeviciute, ... Proceedings of the National Academy of Sciences 110 (22), 9124-9129, 2013 | 253 | 2013 |
Relapse induced by cues predicting cocaine depends on rapid, transient synaptic potentiation CD Gipson, YM Kupchik, H Shen, KJ Reissner, CA Thomas, PW Kalivas Neuron 77 (5), 867-872, 2013 | 223 | 2013 |
Rapid, transient synaptic plasticity in addiction CD Gipson, YM Kupchik, PW Kalivas Neuropharmacology 76, 276-286, 2014 | 165 | 2014 |
The Effect of< i> N</i>-Acetylcysteine in the Nucleus Accumbens on Neurotransmission and Relapse to Cocaine YM Kupchik, K Moussawi, XC Tang, X Wang, BC Kalivas, R Kolokithas, ... Biological Psychiatry, 2011 | 154 | 2011 |
Synaptic plasticity mediating cocaine relapse requires matrix metalloproteinases ACW Smith, YM Kupchik, MD Scofield, CD Gipson, A Wiggins, ... Nature neuroscience 17 (12), 1655-1657, 2014 | 143 | 2014 |
Optogenetic evidence that pallidal projections, not nigral projections, from the nucleus accumbens core are necessary for reinstating cocaine seeking MT Stefanik, YM Kupchik, RM Brown, PW Kalivas Journal of Neuroscience 33 (34), 13654-13662, 2013 | 132 | 2013 |
Loss of plasticity in the D2-accumbens pallidal pathway promotes cocaine seeking JA Heinsbroek, DN Neuhofer, WC Griffin, GS Siegel, AC Bobadilla, ... Journal of Neuroscience 37 (4), 757-767, 2017 | 127 | 2017 |
Optogenetic inhibition of cortical afferents in the nucleus accumbens simultaneously prevents cue-induced transient synaptic potentiation and cocaine-seeking behavior MT Stefanik, YM Kupchik, PW Kalivas Brain structure and function 221, 1681-1689, 2016 | 127 | 2016 |
Addiction-like synaptic impairments in diet-induced obesity RM Brown, YM Kupchik, S Spencer, C Garcia-Keller, DC Spanswick, ... Biological psychiatry 81 (9), 797-806, 2017 | 111 | 2017 |
The direct and indirect pathways of the nucleus accumbens are not what you think YM Kupchik, PW Kalivas Neuropsychopharmacology 42 (1), 369, 2017 | 61 | 2017 |
The story of glutamate in drug addiction and of N-acetylcysteine as a potential pharmacotherapy RM Brown, YM Kupchik, PW Kalivas Jama Psychiatry 70 (9), 895-897, 2013 | 53 | 2013 |
Cocaine dysregulates opioid gating of GABA neurotransmission in the ventral pallidum YM Kupchik, MD Scofield, KC Rice, K Cheng, BP Roques, PW Kalivas Journal of Neuroscience 34 (3), 1057-1066, 2014 | 50 | 2014 |
A novel fast mechanism for GPCR-mediated signal transduction—control of neurotransmitter release YM Kupchik, O Barchad-Avitzur, J Wess, Y Ben-Chaim, I Parnas, ... Journal of cell biology 192 (1), 137-151, 2011 | 47 | 2011 |
Accumbens neuroimmune signaling and dysregulation of astrocytic glutamate transport underlie conditioned nicotine‐seeking behavior MD Namba, YM Kupchik, SM Spencer, C Garcia‐Keller, JG Goenaga, ... Addiction biology 25 (5), e12797, 2020 | 46 | 2020 |
The rostral subcommissural ventral pallidum is a mix of ventral pallidal neurons and neurons from adjacent areas: an electrophysiological study YM Kupchik, PW Kalivas Brain Structure and Function 218, 1487-1500, 2013 | 44 | 2013 |
Glutamatergic mechanisms of comorbidity between acute stress and cocaine self-administration C Garcia-Keller, YM Kupchik, CD Gipson, RM Brown, S Spencer, F Bollati, ... Molecular psychiatry 21 (8), 1063-1069, 2016 | 43 | 2016 |
α2δ-1 signaling in nucleus accumbens is necessary for cocaine-induced relapse S Spencer, RM Brown, GC Quintero, YM Kupchik, CA Thomas, ... Journal of Neuroscience 34 (25), 8605-8611, 2014 | 30 | 2014 |