Oral tecovirimat for the treatment of smallpox DW Grosenbach, K Honeychurch, EA Rose, J Chinsangaram, A Frimm, ... New England Journal of Medicine 379 (1), 44-53, 2018 | 391 | 2018 |
Phase I study of sequential vaccinations with fowlpox-CEA (6D)-TRICOM alone and sequentially with vaccinia-CEA (6D)-TRICOM, with and without granulocyte-macrophage colony … JL Marshall, JL Gulley, PM Arlen, PK Beetham, KY Tsang, R Slack, ... Journal of Clinical Oncology 23 (4), 720-731, 2005 | 354 | 2005 |
A randomized phase II study of concurrent docetaxel plus vaccine versus vaccine alone in metastatic androgen-independent prostate cancer. PM Arlen, JL Gulley, C Parker, L Skarupa, M Pazdur, D Panicali, ... Clinical cancer research: an official journal of the American Association …, 2006 | 342 | 2006 |
IL-2 immunotoxin denileukin diftitox reduces regulatory T cells and enhances vaccine-mediated T-cell immunity MT Litzinger, R Fernando, TJ Curiel, DW Grosenbach, J Schlom, ... Blood, The Journal of the American Society of Hematology 110 (9), 3192-3201, 2007 | 223 | 2007 |
Synergy of vaccine strategies to amplify antigen-specific immune responses and antitumor effects DW Grosenbach, JC Barrientos, J Schlom, JW Hodge Cancer research 61 (11), 4497-4505, 2001 | 185 | 2001 |
An overview of tecovirimat for smallpox treatment and expanded anti-orthopoxvirus applications AT Russo, DW Grosenbach, J Chinsangaram, KM Honeychurch, PG Long, ... Expert review of anti-infective therapy 19 (3), 331-344, 2021 | 166 | 2021 |
A novel inhibitor of dengue virus replication that targets the capsid protein CM Byrd, D Dai, DW Grosenbach, A Berhanu, KF Jones, KB Cardwell, ... Antimicrobial agents and chemotherapy 57 (1), 15-25, 2013 | 159 | 2013 |
Chlamydia psittaci IncA is phosphorylated by the host cell and is exposed on the cytoplasmic face of the developing inclusion DD Rockey, D Grosenbach, DE Hruby, MG Peacock, RA Heinzen, ... Molecular microbiology 24 (1), 217-228, 1997 | 149 | 1997 |
Vaccine therapy of established tumors in the absence of autoimmunity JW Hodge, DW Grosenbach, WM Aarts, DJ Poole, J Schlom Clinical cancer research 9 (5), 1837-1849, 2003 | 139 | 2003 |
Clinical safety of a viral vector based prostate cancer vaccine strategy PM Arlen, L Skarupa, M Pazdur, M Seetharam, KY Tsang, ... The Journal of urology 178 (4), 1515-1520, 2007 | 136 | 2007 |
Antiandrogen, vaccine and combination therapy in patients with nonmetastatic hormone refractory prostate cancer PM Arlen, JL Gulley, N Todd, R Lieberman, SM Steinberg, S Morin, ... The Journal of urology 174 (2), 539-546, 2005 | 130 | 2005 |
Enhanced activation of T cells by dendritic cells engineered to hyperexpress a triad of costimulatory molecules JW Hodge, AN Rad, DW Grosenbach, H Sabzevari, AG Yafal, L Gritz, ... Journal of the National Cancer Institute 92 (15), 1228-1239, 2000 | 113 | 2000 |
Development of the small-molecule antiviral ST-246® as a smallpox therapeutic DW Grosenbach, R Jordan, DE Hruby Future Virology 6 (5), 653-671, 2011 | 110 | 2011 |
Novel benzoxazole inhibitor of dengue virus replication that targets the NS3 helicase CM Byrd, DW Grosenbach, A Berhanu, D Dai, KF Jones, KB Cardwell, ... Antimicrobial agents and chemotherapy 57 (4), 1902-1912, 2013 | 108 | 2013 |
Treatment with the smallpox antiviral tecovirimat (ST-246) alone or in combination with ACAM2000 vaccination is effective as a postsymptomatic therapy for monkeypox virus infection A Berhanu, JT Prigge, PM Silvera, KM Honeychurch, DE Hruby, ... Antimicrobial agents and chemotherapy 59 (7), 4296-4300, 2015 | 103 | 2015 |
Efficacy of tecovirimat (ST-246) in nonhuman primates infected with variola virus (Smallpox) EM Mucker, AJ Goff, JD Shamblin, DW Grosenbach, IK Damon, JM Mehal, ... Antimicrobial agents and chemotherapy 57 (12), 6246-6253, 2013 | 102 | 2013 |
Vaccination of BALB/c Mice with Escherichia coli-Expressed Vaccinia Virus Proteins A27L, B5R, and D8L Protects Mice from Lethal Vaccinia Virus Challenge A Berhanu, RL Wilson, DL Kirkwood-Watts, DS King, TK Warren, SA Lund, ... Journal of virology 82 (7), 3517-3529, 2008 | 101 | 2008 |
Co-administration of tecovirimat and ACAM2000™ in non-human primates: Effect of tecovirimat treatment on ACAM2000 immunogenicity and efficacy versus lethal monkeypox virus … AT Russo, A Berhanu, CB Bigger, J Prigge, PM Silvera, DW Grosenbach, ... Vaccine 38 (3), 644-654, 2020 | 98 | 2020 |
ST-246 is a key antiviral to inhibit the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping S Duraffour, MM Lorenzo, G Zöller, D Topalis, D Grosenbach, DE Hruby, ... Journal of Antimicrobial Chemotherapy 70 (5), 1367-1380, 2015 | 86 | 2015 |
Palmitylation of the vaccinia virus 37-kDa major envelope antigen: identification of a conserved acceptor motif and biological relevance DW Grosenbach, DO Ulaeto, DE Hruby Journal of Biological Chemistry 272 (3), 1956-1964, 1997 | 85 | 1997 |