The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins OJ Harrison, X Jin, S Hong, F Bahna, G Ahlsen, J Brasch, Y Wu, ... Structure 19 (2), 244-256, 2011 | 459 | 2011 |
Linking molecular affinity and cellular specificity in cadherin-mediated adhesion P Katsamba, K Carroll, G Ahlsen, F Bahna, J Vendome, S Posy, ... Proceedings of the National Academy of Sciences 106 (28), 11594-11599, 2009 | 282 | 2009 |
Transforming binding affinities from three dimensions to two with application to cadherin clustering Y Wu, J Vendome, L Shapiro, A Ben-Shaul, B Honig Nature 475 (7357), 510-513, 2011 | 246 | 2011 |
Two-step adhesive binding by classical cadherins OJ Harrison, F Bahna, PS Katsamba, X Jin, J Brasch, J Vendome, ... Nature structural & molecular biology 17 (3), 348-357, 2010 | 239 | 2010 |
Structure and drug resistance of the Plasmodium falciparum transporter PfCRT J Kim, YZ Tan, KJ Wicht, SK Erramilli, SK Dhingra, J Okombo, J Vendome, ... Nature 576 (7786), 315-320, 2019 | 167 | 2019 |
T-cadherin structures reveal a novel adhesive binding mechanism C Ciatto, F Bahna, N Zampieri, HC VanSteenhouse, PS Katsamba, ... Nature structural & molecular biology 17 (3), 339-347, 2010 | 166 | 2010 |
The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain J Koehnke, A Bent, WE Houssen, D Zollman, F Morawitz, S Shirran, ... Nature structural & molecular biology 19 (8), 767, 2012 | 154 | 2012 |
Molecular design principles underlying β-strand swapping in the adhesive dimerization of cadherins J Vendome, S Posy, X Jin, F Bahna, G Ahlsen, L Shapiro, B Honig Nature structural & molecular biology 18 (6), 693-700, 2011 | 131 | 2011 |
Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies C Deng, MR Lipstein, L Scotto, XO Jirau Serrano, MA Mangone, S Li, ... Blood, The Journal of the American Society of Hematology 129 (1), 88-99, 2017 | 125 | 2017 |
Nectin ectodomain structures reveal a canonical adhesive interface OJ Harrison, J Vendome, J Brasch, X Jin, S Hong, PS Katsamba, ... Nature structural & molecular biology 19 (9), 906-915, 2012 | 125 | 2012 |
Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation VI Petrou, CM Herrera, KM Schultz, OB Clarke, J Vendome, D Tomasek, ... Science 351 (6273), 608-612, 2016 | 115 | 2016 |
Splice form dependence of β-neurexin/neuroligin binding interactions J Koehnke, PS Katsamba, G Ahlsen, F Bahna, J Vendome, B Honig, ... Neuron 67 (1), 61-74, 2010 | 114 | 2010 |
Structural and energetic determinants of adhesive binding specificity in type I cadherins J Vendome, K Felsovalyi, H Song, Z Yang, X Jin, J Brasch, OJ Harrison, ... Proceedings of the National Academy of Sciences 111 (40), E4175-E4184, 2014 | 96 | 2014 |
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance LA Kirkman, W Zhan, J Visone, A Dziedziech, PK Singh, H Fan, X Tong, ... Proceedings of the National Academy of Sciences 115 (29), E6863-E6870, 2018 | 85 | 2018 |
Loop L5 acts as a conformational latch in the mitotic kinesin Eg5 WM Behnke-Parks, J Vendome, Z Maliga, C Moores, S Rosenfeld Biophysical Journal 100 (3), 530a, 2011 | 64 | 2011 |
Identification of a Novel 1,2,3,4-Tetrahydrobenzo[b][1,6]naphthyridine Analogue as a Potent Phosphodiesterase 5 Inhibitor with Improved Aqueous Solubility for the … J Fiorito, J Vendome, F Saeed, A Staniszewski, H Zhang, S Yan, SX Deng, ... Journal of medicinal chemistry 60 (21), 8858-8875, 2017 | 54 | 2017 |
Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca2+-free interdomain linkers X Jin, MA Walker, K Felsövályi, J Vendome, F Bahna, S Mannepalli, ... Proceedings of the National Academy of Sciences 109 (3), E127-E134, 2012 | 52 | 2012 |
The Discovery of New Cyanobactins from Cyanothece PCC 7425 Defines a New Signature for Processing of Patellamides WE Houssen, J Koehnke, D Zollman, J Vendome, A Raab, MCM Smith, ... ChemBioChem 13 (18), 2683-2689, 2012 | 46 | 2012 |
Enhancing hit discovery in virtual screening through absolute protein–ligand binding free-energy calculations W Chen, D Cui, SV Jerome, M Michino, EB Lenselink, DJ Huggins, ... Journal of Chemical Information and Modeling 63 (10), 3171-3185, 2023 | 44 | 2023 |
Molecular modeling of wild-type and D816V c-Kit inhibition based on ATP-competitive binding of ellipticine derivatives to tyrosine kinases J Vendôme, S Letard, F Martin, F Svinarchuk, P Dubreuil, C Auclair, ... Journal of medicinal chemistry 48 (20), 6194-6201, 2005 | 41 | 2005 |