关注
Adel A. Rashad
Adel A. Rashad
Drexel University College of Medicine
在 drexelmed.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Synthesis and antiviral activity of new pyrazole and thiazole derivatives
OI El-Sabbagh, MM Baraka, SM Ibrahim, C Pannecouque, G Andrei, ...
European journal of medicinal chemistry 44 (9), 3746-3753, 2009
4692009
FDA-approved drugs with potent in vitro antiviral activity against severe acute respiratory syndrome coronavirus 2
A Mostafa, A Kandeil, Y AMM Elshaier, O Kutkat, Y Moatasim, AA Rashad, ...
Pharmaceuticals 13 (12), 443, 2020
1432020
Chikungunya virus: emerging targets and new opportunities for medicinal chemistry
AA Rashad, S Mahalingam, PA Keller
Journal of Medicinal Chemistry 57 (4), 1147-1166, 2014
1072014
Bioactive polyphenolic compounds showing strong antiviral activities against severe acute respiratory syndrome coronavirus 2
A Kandeil, A Mostafa, O Kutkat, Y Moatasim, AA Al-Karmalawy, ...
Pathogens 10 (6), 758, 2021
842021
Peptide triazole inactivators of HIV-1 utilize a conserved two-cavity binding site at the junction of the inner and outer domains of Env gp120
R Aneja, AA Rashad, H Li, RV Kalyana Sundaram, C Duffy, LD Bailey, ...
Journal of medicinal chemistry 58 (9), 3843-3858, 2015
492015
Exploring modifications of an HIV-1 capsid inhibitor: design, synthesis, and mechanism of action
JP Xu, AC Francis, ME Meuser, M Mankowski, RG Ptak, AA Rashad, ...
Journal of drug design and research 5 (2), 2018
482018
Structure based design towards the identification of novel binding sites and inhibitors for the chikungunya virus envelope proteins
AA Rashad, PA Keller
Journal of Molecular Graphics and Modelling 44, 241-252, 2013
402013
Macrocyclic Envelope Glycoprotein Antagonists that Irreversibly Inactivate HIV-1 before Host Cell Encounter
AA Rashad, RV Kalyana Sundaram, R Aneja, C Duffy, I Chaiken
Journal of medicinal chemistry 58 (18), 7603-7608, 2015
372015
Design, synthesis and preliminary antiviral screening of new N-phenylpyrazole and dihydroisoxazole derivatives
AA Rashad, OI El-Sabbagh, MM Baraka, SM Ibrahim, C Pannecouque, ...
Medicinal chemistry research 19, 1025-1035, 2010
272010
Chemical optimization of macrocyclic HIV-1 inactivators for improving potency and increasing the structural diversity at the triazole ring
AA Rashad, K Acharya, A Haftl, R Aneja, A Dick, AP Holmes, I Chaiken
Organic & biomolecular chemistry 15 (37), 7770-7782, 2017
262017
Synthesis, molecular modeling and anti-inflammatory screening of new 1, 2, 3-benzotriazinone derivatives
TS Ibrahim, AA Rashad, ZK Abdel-Samii, SA El-Feky, MK Abdel-Hamid, ...
Medicinal Chemistry Research 21, 4369-4380, 2012
262012
Lytic inactivation of human immunodeficiency virus by dual engagement of gp120 and gp41 domains in the virus Env protein trimer
B Parajuli, K Acharya, R Yu, B Ngo, AA Rashad, CF Abrams, IM Chaiken
Biochemistry 55 (44), 6100-6114, 2016
222016
Facile Synthesis and Preliminary Structure–Activity Analysis of New Sulfonamides Against Trypanosoma brucei
AA Rashad, AJ Jones, VM Avery, J Baell, PA Keller
ACS Medicinal Chemistry Letters 5 (5), 496-500, 2014
182014
Disulfide sensitivity in the Env protein underlies lytic inactivation of HIV-1 by peptide triazole thiols
LD Bailey, RV Kalyana Sundaram, H Li, C Duffy, R Aneja, ...
ACS chemical biology 10 (12), 2861-2873, 2015
162015
inhibition of DC-SIGN-mediated HIV-1 infection by complementary actions of dendritic cell receptor antagonists and Env-targeting virus inactivators
S Pustylnikov, RS Dave, ZK Khan, V Porkolab, AA Rashad, M Hutchinson, ...
AIDS research and human retroviruses 32 (1), 93-100, 2016
152016
Discovery of a first-in-class inhibitor of sulfide: quinone oxidoreductase that protects against adverse cardiac remodelling and heart failure
MR Jackson, KD Cox, SDP Baugh, L Wakeen, AA Rashad, PYS Lam, ...
Cardiovascular research 118 (7), 1771-1784, 2022
142022
Field-based affinity optimization of a novel azabicyclohexane scaffold HIV-1 entry inhibitor
ME Meuser, AA Rashad, G Ozorowski, A Dick, AB Ward, S Cocklin
Molecules 24 (8), 1581, 2019
142019
Pharmacokinetic stability of macrocyclic peptide triazole HIV‐1 inactivators alone and in liposomes
R Aneja, A Grigoletto, A Nangarlia, AA Rashad, S Wrenn, JM Jacobson, ...
Journal of peptide science 25 (4), e3155, 2019
132019
Peptide triazole inactivators of HIV-1: how do they work and what is their potential?
I Chaiken, AA Rashad
Future medicinal chemistry 7 (17), 2305-2310, 2015
132015
Kinetic characterization of novel HIV-1 entry inhibitors: discovery of a relationship between off-rate and potency
ME Meuser, MB Murphy, AA Rashad, S Cocklin
Molecules 23 (8), 1940, 2018
122018
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