Synthesis and antiviral activity of new pyrazole and thiazole derivatives OI El-Sabbagh, MM Baraka, SM Ibrahim, C Pannecouque, G Andrei, ... European journal of medicinal chemistry 44 (9), 3746-3753, 2009 | 469 | 2009 |
FDA-approved drugs with potent in vitro antiviral activity against severe acute respiratory syndrome coronavirus 2 A Mostafa, A Kandeil, Y AMM Elshaier, O Kutkat, Y Moatasim, AA Rashad, ... Pharmaceuticals 13 (12), 443, 2020 | 143 | 2020 |
Chikungunya virus: emerging targets and new opportunities for medicinal chemistry AA Rashad, S Mahalingam, PA Keller Journal of Medicinal Chemistry 57 (4), 1147-1166, 2014 | 107 | 2014 |
Bioactive polyphenolic compounds showing strong antiviral activities against severe acute respiratory syndrome coronavirus 2 A Kandeil, A Mostafa, O Kutkat, Y Moatasim, AA Al-Karmalawy, ... Pathogens 10 (6), 758, 2021 | 84 | 2021 |
Peptide triazole inactivators of HIV-1 utilize a conserved two-cavity binding site at the junction of the inner and outer domains of Env gp120 R Aneja, AA Rashad, H Li, RV Kalyana Sundaram, C Duffy, LD Bailey, ... Journal of medicinal chemistry 58 (9), 3843-3858, 2015 | 49 | 2015 |
Exploring modifications of an HIV-1 capsid inhibitor: design, synthesis, and mechanism of action JP Xu, AC Francis, ME Meuser, M Mankowski, RG Ptak, AA Rashad, ... Journal of drug design and research 5 (2), 2018 | 48 | 2018 |
Structure based design towards the identification of novel binding sites and inhibitors for the chikungunya virus envelope proteins AA Rashad, PA Keller Journal of Molecular Graphics and Modelling 44, 241-252, 2013 | 40 | 2013 |
Macrocyclic Envelope Glycoprotein Antagonists that Irreversibly Inactivate HIV-1 before Host Cell Encounter AA Rashad, RV Kalyana Sundaram, R Aneja, C Duffy, I Chaiken Journal of medicinal chemistry 58 (18), 7603-7608, 2015 | 37 | 2015 |
Design, synthesis and preliminary antiviral screening of new N-phenylpyrazole and dihydroisoxazole derivatives AA Rashad, OI El-Sabbagh, MM Baraka, SM Ibrahim, C Pannecouque, ... Medicinal chemistry research 19, 1025-1035, 2010 | 27 | 2010 |
Chemical optimization of macrocyclic HIV-1 inactivators for improving potency and increasing the structural diversity at the triazole ring AA Rashad, K Acharya, A Haftl, R Aneja, A Dick, AP Holmes, I Chaiken Organic & biomolecular chemistry 15 (37), 7770-7782, 2017 | 26 | 2017 |
Synthesis, molecular modeling and anti-inflammatory screening of new 1, 2, 3-benzotriazinone derivatives TS Ibrahim, AA Rashad, ZK Abdel-Samii, SA El-Feky, MK Abdel-Hamid, ... Medicinal Chemistry Research 21, 4369-4380, 2012 | 26 | 2012 |
Lytic inactivation of human immunodeficiency virus by dual engagement of gp120 and gp41 domains in the virus Env protein trimer B Parajuli, K Acharya, R Yu, B Ngo, AA Rashad, CF Abrams, IM Chaiken Biochemistry 55 (44), 6100-6114, 2016 | 22 | 2016 |
Facile Synthesis and Preliminary Structure–Activity Analysis of New Sulfonamides Against Trypanosoma brucei AA Rashad, AJ Jones, VM Avery, J Baell, PA Keller ACS Medicinal Chemistry Letters 5 (5), 496-500, 2014 | 18 | 2014 |
Disulfide sensitivity in the Env protein underlies lytic inactivation of HIV-1 by peptide triazole thiols LD Bailey, RV Kalyana Sundaram, H Li, C Duffy, R Aneja, ... ACS chemical biology 10 (12), 2861-2873, 2015 | 16 | 2015 |
inhibition of DC-SIGN-mediated HIV-1 infection by complementary actions of dendritic cell receptor antagonists and Env-targeting virus inactivators S Pustylnikov, RS Dave, ZK Khan, V Porkolab, AA Rashad, M Hutchinson, ... AIDS research and human retroviruses 32 (1), 93-100, 2016 | 15 | 2016 |
Discovery of a first-in-class inhibitor of sulfide: quinone oxidoreductase that protects against adverse cardiac remodelling and heart failure MR Jackson, KD Cox, SDP Baugh, L Wakeen, AA Rashad, PYS Lam, ... Cardiovascular research 118 (7), 1771-1784, 2022 | 14 | 2022 |
Field-based affinity optimization of a novel azabicyclohexane scaffold HIV-1 entry inhibitor ME Meuser, AA Rashad, G Ozorowski, A Dick, AB Ward, S Cocklin Molecules 24 (8), 1581, 2019 | 14 | 2019 |
Pharmacokinetic stability of macrocyclic peptide triazole HIV‐1 inactivators alone and in liposomes R Aneja, A Grigoletto, A Nangarlia, AA Rashad, S Wrenn, JM Jacobson, ... Journal of peptide science 25 (4), e3155, 2019 | 13 | 2019 |
Peptide triazole inactivators of HIV-1: how do they work and what is their potential? I Chaiken, AA Rashad Future medicinal chemistry 7 (17), 2305-2310, 2015 | 13 | 2015 |
Kinetic characterization of novel HIV-1 entry inhibitors: discovery of a relationship between off-rate and potency ME Meuser, MB Murphy, AA Rashad, S Cocklin Molecules 23 (8), 1940, 2018 | 12 | 2018 |