Compounds and methods for site directed mutations in eukaryotic cells EB Kmiec US Patent 5,565,350, 1996 | 590 | 1996 |
Correction of the mutation responsible for sickle cell anemia by an RNA-DNA oligonucleotide A Cole-Strauss, K Yoon, Y Xiang, BC Byrne, MC Rice, J Gryn, ... Science 273 (5280), 1386-1389, 1996 | 478 | 1996 |
Targeted gene correction of episomal DNA in mammalian cells mediated by a chimeric RNA. DNA oligonucleotide. K Yoon, A Cole-Strauss, EB Kmiec Proceedings of the National Academy of Sciences 93 (5), 2071-2076, 1996 | 318 | 1996 |
Disruption of muREC2/RAD51L1 in Mice Results in Early Embryonic Lethality Which Can Be Partially Rescued in a p53−/− Background Z Shu, S Smith, L Wang, MC Rice, EB Kmiec Molecular and cellular biology 19 (12), 8686-8693, 1999 | 188 | 1999 |
Beta protein of bacteriophage lambda promotes renaturation of DNA. E Kmiec, WK Holloman Journal of Biological Chemistry 256 (24), 12636-12639, 1981 | 182 | 1981 |
The DNA strand of chimeric RNA/DNA oligonucleotides can direct gene repair/conversion activity in mammalian and plant cell-free extracts HB Gamper, H Parekh, MC Rice, M Bruner, H Youkey, EB Kmiec Nucleic Acids Research 28 (21), 4332-4339, 2000 | 176 | 2000 |
Targeted gene repair directed by the chimeric RNA/DNA oligonucleotide in a mammalian cell-free extract A Cole-Strauss, H Gamper, M Muñoz, N Cheng, EB Kmiec, WK Holloman Nucleic acids research 27 (5), 1323-1330, 1999 | 169 | 1999 |
Targeted nucleotide exchange in the alkaline phosphatase gene of HuH-7 cells mediated by a chimeric RNA/DNA oligonucleotide BT Kren, A Cole-Strauss, EB Kmiec, CJ Steer Hepatology 25 (6), 1462-1468, 1997 | 162 | 1997 |
A plausible mechanism for gene correction by chimeric oligonucleotides HB Gamper, A Cole-Strauss, R Metz, H Parekh, R Kumar, EB Kmiec Biochemistry 39 (19), 5808-5816, 2000 | 150 | 2000 |
Targeted chromosomal genomic alterations with modified single stranded oligonucleotides EB Kmiec, HB Gamper, MC Rice US Patent 6,936,467, 2005 | 146 | 2005 |
Homologous pairing of DNA molecules by Ustilago rec1 protein is promoted by sequences of Z-DNA EB Kmiec, WK Holloman Cell 44 (4), 545-554, 1986 | 140 | 1986 |
Homologous pairing of DNA molecules promoted by a protein from Ustilago E Kmiec, WK Holloman Cell 29 (2), 367-374, 1982 | 130 | 1982 |
Targeted chromosomal genomic alterations with modified single stranded oligonucleotides EB Kmiec, HB Gamper, MC Rice US Patent 7,226,785, 2007 | 123 | 2007 |
Gene therapy progress and prospects: targeted gene repair H Parekh-Olmedo, L Ferrara, E Brachman, EB Kmiec Gene therapy 12 (8), 639-646, 2005 | 123 | 2005 |
DNA breakage and induction of DNA damage response proteins precede the appearance of visible mutant huntingtin aggregates J Illuzzi, S Yerkes, H Parekh‐Olmedo, EB Kmiec Journal of neuroscience research 87 (3), 733-747, 2009 | 119 | 2009 |
In vivo gene repair of point and frameshift mutations directed by chimeric RNA/DNA oligonucleotides and modified single-stranded oligonucleotides L Liu, MC Rice, EB Kmiec Nucleic Acids Research 29 (20), 4238-4250, 2001 | 119 | 2001 |
Methods and compounds for curing diseases caused by mutations EB Kmiec, A Cole-Strauss, K Yoon US Patent 5,760,012, 1998 | 117 | 1998 |
Chimeric mutational vectors having non-natural nucleotides EB Kmiec US Patent 5,731,181, 1998 | 116 | 1998 |
Isolation of human and mouse genes based on homology to REC2, a recombinational repair gene from the fungus Ustilago maydis MC Rice, ST Smith, F Bullrich, P Havre, EB Kmiec Proceedings of the National Academy of Sciences 94 (14), 7417-7422, 1997 | 113 | 1997 |
Left-handed DNA and the synaptic pairing reaction promoted by Ustilago recl protein EB Kmiec, KJ Angelides, WK Holloman Cell 40 (1), 139-145, 1985 | 112 | 1985 |