Treatment of hypertension in patients 80 years of age or older NS Beckett, R Peters, AE Fletcher, JA Staessen, L Liu, D Dumitrascu, ... New England Journal of Medicine 358 (18), 1887-1898, 2008 | 4651 | 2008 |
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Aβ amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial CW Ritchie, AI Bush, A Mackinnon, S Macfarlane, M Mastwyk, ... Archives of neurology 60 (12), 1685-1691, 2003 | 1231 | 2003 |
Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial R Peters, N Beckett, F Forette, J Tuomilehto, R Clarke, C Ritchie, ... The Lancet Neurology 7 (8), 683-689, 2008 | 1005 | 2008 |
Donepezil and memantine for moderate-to-severe Alzheimer's disease R Howard, R McShane, J Lindesay, C Ritchie, A Baldwin, R Barber, ... New England Journal of Medicine 366 (10), 893-903, 2012 | 920 | 2012 |
Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial L Lannfelt, K Blennow, H Zetterberg, S Batsman, D Ames, J Harrison, ... The Lancet Neurology 7 (9), 779-786, 2008 | 847 | 2008 |
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Aβ PA Adlard, RA Cherny, DI Finkelstein, E Gautier, E Robb, M Cortes, ... Neuron 59 (1), 43-55, 2008 | 787 | 2008 |
Donanemab in early symptomatic Alzheimer disease: the TRAILBLAZER-ALZ 2 randomized clinical trial JR Sims, JA Zimmer, CD Evans, M Lu, P Ardayfio, JD Sparks, AM Wessels, ... JAMA, 2023 | 556 | 2023 |
GWAS on family history of Alzheimer’s disease RE Marioni, SE Harris, Q Zhang, AF McRae, SP Hagenaars, WD Hill, ... Translational psychiatry 8 (1), 99, 2018 | 524 | 2018 |
A phase II trial of tideglusib in Alzheimer's disease. ST Lovestone S, Boada M, Dubois B, Hüll M, Rinne JO, Huppertz HJ, Calero M ... Journal of Alzheimer's Disease 45 (1), 75-88, 2015 | 498 | 2015 |
The impact of general and regional anesthesia on the incidence of post-operative cognitive dysfunction and post-operative delirium: a systematic review with meta-analysis SE Mason, A Noel-Storr, CW Ritchie Journal of Alzheimer's Disease 22 (s3), S67-S79, 2010 | 496 | 2010 |
The incidence of delirium associated with orthopedic surgery: a meta-analytic review AJ Bruce, CW Ritchie, R Blizard, R Lai, P Raven International psychogeriatrics 19 (2), 197-214, 2007 | 467 | 2007 |
PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses NG Faux, CW Ritchie, A Gunn, A Rembach, A Tsatsanis, J Bedo, ... Journal of Alzheimer's Disease 20 (2), 509-516, 2010 | 432 | 2010 |
Designing prevention programmes to reduce incidence of dementia: prospective cohort study of modifiable risk factors K Ritchie, I Carrière, CW Ritchie, C Berr, S Artero, ML Ancelin Bmj 341, 2010 | 296 | 2010 |
Metaanalysis of randomized trials of the efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer disease CW Ritchie, D Ames, T Clayton, R Lai The American Journal of Geriatric Psychiatry 12 (4), 358-369, 2004 | 274 | 2004 |
Adaptive platform trials: definition, design, conduct and reporting considerations Nature Reviews Drug Discovery 18 (10), 797-807, 2019 | 249 | 2019 |
CSF tau and the CSF tau/ABeta ratio for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI) C Ritchie, AH Noel‐Storr, O Ukoumunne, EC Ladds, S Martin Cochrane Database of Systematic Reviews, 2017 | 240 | 2017 |
Clinical practice with anti-dementia drugs: a revised (third) consensus statement from the British Association for Psychopharmacology JT O’Brien, C Holmes, M Jones, R Jones, G Livingston, I McKeith, P Mittler, ... Journal of Psychopharmacology 31 (2), 147-168, 2017 | 234 | 2017 |
A systematic review of the scientific evidence for the efficacy of a palliative care approach in advanced dementia EL Sampson, CW Ritchie, R Lai, PW Raven, MR Blanchard International Psychogeriatrics 17 (1), 31-40, 2005 | 234 | 2005 |
Clinical practice with anti-dementia drugs: a revised (second) consensus statement from the British Association for Psychopharmacology JT O’brien, A Burns Journal of Psychopharmacology 25 (8), 997-1019, 2011 | 233 | 2011 |
A randomized, double‐blind, placebo‐controlled trial of donepezil hydrochloride (Aricept) for reducing the incidence of postoperative delirium after elective total hip replacement EL Sampson, PR Raven, PN Ndhlovu, A Vallance, N Garlick, J Watts, ... International Journal of Geriatric Psychiatry: A journal of the psychiatry …, 2007 | 230 | 2007 |