| Automated genome mining for natural products MHT Li, PMU Ung, J Zajkowski, S Garneau-Tsodikova, DH Sherman BMC bioinformatics 10, 1-10, 2009 | 321 | 2009 |
| SLC transporters: structure, function, and drug discovery C Colas, PMU Ung, A Schlessinger Medchemcomm 7 (6), 1069-1081, 2016 | 195 | 2016 |
| Binding of a small molecule at a protein–protein interface regulates the chaperone activity of hsp70–hsp40 S Wisén, EB Bertelsen, AD Thompson, S Patury, P Ung, L Chang, ... ACS chemical biology 5 (6), 611-622, 2010 | 172 | 2010 |
| CSAR benchmark exercise of 2010: selection of the protein–ligand complexes JB Dunbar Jr, RD Smith, CY Yang, PMU Ung, KW Lexa, NA Khazanov, ... Journal of chemical information and modeling 51 (9), 2036-2046, 2011 | 162 | 2011 |
| CSAR benchmark exercise of 2010: combined evaluation across all submitted scoring functions RD Smith, JB Dunbar Jr, PMU Ung, EX Esposito, CY Yang, S Wang, ... Journal of chemical information and modeling 51 (9), 2115-2131, 2011 | 158 | 2011 |
| Molecular basis for redox activation of epidermal growth factor receptor kinase TH Truong, PMU Ung, PB Palde, CE Paulsen, A Schlessinger, KS Carroll Cell chemical biology 23 (7), 837-848, 2016 | 118 | 2016 |
| Chemical screens against a reconstituted multiprotein complex: myricetin blocks DnaJ regulation of DnaK through an allosteric mechanism L Chang, Y Miyata, PMU Ung, EB Bertelsen, TJ McQuade, HA Carlson, ... Chemistry & biology 18 (2), 210-221, 2011 | 110 | 2011 |
| Mutagenesis reveals the complex relationships between ATPase rate and the chaperone activities of Escherichia coli heat shock protein 70 (Hsp70/DnaK) L Chang, AD Thompson, P Ung, HA Carlson, JE Gestwicki Journal of Biological Chemistry 285 (28), 21282-21291, 2010 | 83 | 2010 |
| Redefining the protein kinase conformational space with machine learning PMU Ung, R Rahman, A Schlessinger Cell chemical biology 25 (7), 916-924. e2, 2018 | 81 | 2018 |
| Inhibitor discovery for the human GLUT1 from homology modeling and virtual screening PMU Ung, W Song, L Cheng, X Zhao, H Hu, L Chen, A Schlessinger ACS chemical biology 11 (7), 1908-1916, 2016 | 61 | 2016 |
| A whole-animal platform to advance a clinical kinase inhibitor into new disease space M Sonoshita, AP Scopton, PMU Ung, MA Murray, L Silber, AY Maldonado, ... Nature Chemical Biology 14, 291-298, 2018 | 56 | 2018 |
| Identifying binding hot spots on protein surfaces by mixed‐solvent molecular dynamics: HIV‐1 protease as a test case PMU Ung, P Ghanakota, SE Graham, KW Lexa, HA Carlson Biopolymers 105 (1), 21-34, 2016 | 53 | 2016 |
| An IRAK1–PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy PH Liu, RB Shah, Y Li, A Arora, PMU Ung, R Raman, A Gorbatenko, ... Nature cell biology 21 (2), 203-213, 2019 | 48 | 2019 |
| DFGmodel: predicting protein kinase structures in inactive states for structure-based discovery of type-II inhibitors PMU Ung, A Schlessinger Biophysical Journal 108 (2), 474a, 2015 | 46 | 2015 |
| Chemical probes that selectively recognize the earliest Aβ oligomers in complex mixtures AA Reinke, PMU Ung, JJ Quintero, HA Carlson, JE Gestwicki Journal of the American Chemical Society 132 (50), 17655-17657, 2010 | 46 | 2010 |
| Novel selective thiadiazine DYRK1A inhibitor lead scaffold with human pancreatic β-cell proliferation activity K Kumar, PMU Ung, P Wang, H Wang, H Li, MK Andrews, AF Stewart, ... European journal of medicinal chemistry 157, 1005-1016, 2018 | 45 | 2018 |
| A poke in the eye: inhibiting HIV‐1 protease through its flap‐recognition pocket KL Damm, PMU Ung, JJ Quintero, JE Gestwicki, HA Carlson Biopolymers: Original Research on Biomolecules 89 (8), 643-652, 2008 | 45 | 2008 |
| Exploiting allosteric properties of RAF and MEK inhibitors to target therapy-resistant tumors driven by oncogenic BRAF signaling C Adamopoulos, TA Ahmed, MR Tucker, PMU Ung, M Xiao, Z Karoulia, ... Cancer Discovery, 2021 | 37 | 2021 |
| Structures of ligand-occupied β-Klotho complexes reveal a molecular mechanism underlying endocrine FGF specificity and activity ES Kuzina, PMU Ung, J Mohanty, F Tome, J Choi, E Pardon, J Steyaert, ... Proceedings of the National Academy of Sciences 116 (16), 7819-7824, 2019 | 34 | 2019 |
| Identification of a G-protein-independent activator of GIRK channels Y Zhao, PMU Ung, G Zahoránszky-Kőhalmi, AV Zakharov, NJ Martinez, ... Cell reports 31 (11), 2020 | 29 | 2020 |
Avner SchlessingerProfessor, Icahn School of Medicine at Mount Sinai, New York, NY在 mssm.edu 的电子邮件经过验证
