Identification of a small molecule with activity against drug-resistant and persistent tuberculosis F Wang, D Sambandan, R Halder, J Wang, SM Batt, B Weinrick, I Ahmad, ... Proceedings of the National Academy of Sciences 110 (27), E2510-E2517, 2013 | 251 | 2013 |
Benzothiazinones: Prodrugs That Covalently Modify the Decaprenylphosphoryl-β-d-ribose 2′-epimerase DprE1 of Mycobacterium tuberculosis C Trefzer, M Rengifo-Gonzalez, MJ Hinner, P Schneider, V Makarov, ... Journal of the American Chemical Society 132 (39), 13663-13665, 2010 | 230 | 2010 |
Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-d-ribofuranose 2′-Oxidase DprE1 C Trefzer, H Škovierová, S Buroni, A Bobovská, S Nenci, E Molteni, ... Journal of the American Chemical Society 134 (2), 912-915, 2012 | 206 | 2012 |
The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity GE Winter, B Radic, C Mayor-Ruiz, VA Blomen, C Trefzer, RK Kandasamy, ... Nature chemical biology 10 (9), 768-773, 2014 | 175 | 2014 |
The RNA‐binding protein HuR/ELAVL1 regulates IFN‐β mRNA abundance and the type I IFN response B Herdy, T Karonitsch, GI Vladimer, CSH Tan, A Stukalov, C Trefzer, ... European journal of immunology 45 (5), 1500-1511, 2015 | 57 | 2015 |
A modular synthesis of modified phosphoanhydrides A Hofer, GS Cremosnik, AC Müller, R Giambruno, C Trefzer, ... Chemistry–A European Journal 21 (28), 10116-10122, 2015 | 48 | 2015 |
NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation MP Licciardello, MK Müllner, G Dürnberger, C Kerzendorfer, B Boidol, ... Oncogene 34 (29), 3780-3790, 2015 | 48 | 2015 |
New WS9326A Derivatives and One New Annimycin Derivative with Antimalarial Activity are Produced by Streptomyces asterosporus DSM 41452 and Its Mutant S Zhang, J Zhu, DL Zechel, C Jessen‐Trefzer, RT Eastman, T Paululat, ... ChemBioChem 19 (3), 272-279, 2018 | 33 | 2018 |
Targeting a cell state common to triple‐negative breast cancers MK Muellner, B Mair, Y Ibrahim, C Kerzendorfer, H Lechtermann, ... Molecular Systems Biology 11 (2), 789, 2015 | 24 | 2015 |
Trehalose conjugation enhances toxicity of photosensitizers against mycobacteria AK Dutta, E Choudhary, X Wang, M Záhorszka, M Forbak, P Lohner, ... ACS Central Science 5 (4), 644-650, 2019 | 23 | 2019 |
Inside a Shell—Organometallic Catalysis Inside Encapsulin Nanoreactors P Lohner, M Zmyslia, J Thurn, JK Pape, R Gerasimaitė, ... Angewandte Chemie 133 (44), 24028-24034, 2021 | 19 | 2021 |
Magic spot nucleotides: tunable target-specific chemoenzymatic synthesis TM Haas, P Ebensperger, VB Eisenbeis, C Nopper, T Dürr, N Jork, ... Chemical communications 55 (37), 5339-5342, 2019 | 16 | 2019 |
Pyridinium modified anthracenes and their endoperoxides provide a tunable scaffold with activity against gram-positive and gram-negative bacteria X Wang, T Bittner, M Milanov, L Kaul, S Mundinger, HG Koch, ... ACS Infectious Diseases 7 (8), 2073-2080, 2021 | 15 | 2021 |
Four phosphates at one blow: Access to pentaphosphorylated magic spot nucleotides and their analysis by capillary electrophoresis TM Haas, D Qiu, M Häner, L Angebauer, A Ripp, J Singh, HG Koch, ... The Journal of Organic Chemistry 85 (22), 14496-14506, 2020 | 14 | 2020 |
Wide Distribution of Foxicin Biosynthetic Gene Clusters in Streptomyces Strains – An Unusual Secondary Metabolite with Various Properties A Greule, M Marolt, D Deubel, I Peintner, S Zhang, C Jessen-Trefzer, ... Frontiers in microbiology 8, 221, 2017 | 13 | 2017 |
Detection and characterization of a mycobacterial L-arabinofuranose ABC transporter identified with a rapid lipoproteomics protocol M Li, C Mueller, K Froehlich, O Gorka, L Zhang, O Gross, O Schilling, ... Cell Chemical Biology 26 (6), 852-862. e6, 2019 | 10 | 2019 |
A Dual‐Metal‐Catalyzed Sequential Cascade Reaction in an Engineered Protein Cage P Ebensperger, M Zmyslia, P Lohner, J Braunreuther, B Deuringer, ... Angewandte Chemie 135 (16), e202218413, 2023 | 7 | 2023 |
Artificial metalloenzymes in a nutshell: the quartet for efficient catalysis P Ebensperger, C Jessen-Trefzer Biological Chemistry 403 (4), 403-412, 2022 | 7 | 2022 |
The Two-Component Locus MSMEG_0244/0246 Together With MSMEG_0243 Affects Biofilm Assembly in M. smegmatis Correlating With Changes in … M Li, H Gašparovič, X Weng, S Chen, J Korduláková, C Jessen-Trefzer Frontiers in Microbiology 11, 570606, 2020 | 5 | 2020 |
Understanding the mechanism of action of pyrrolo [3, 2-b] quinoxaline-derivatives as kinase inhibitors A Unzue, C Jessen-Trefzer, D Spiliotopoulos, E Gaudio, C Tarantelli, ... RSC Medicinal Chemistry 11 (6), 665-675, 2020 | 4 | 2020 |