Phospholipase A2 Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention EA Dennis, J Cao, YH Hsu, V Magrioti, G Kokotos Chemical reviews 111 (10), 6130-6185, 2011 | 1253 | 2011 |
Cytosolic group IVA and calcium-independent group VIA phospholipase A2s act on distinct phospholipid pools in zymosan-stimulated mouse peritoneal macrophages L Gil-de-Gómez, AM Astudillo, C Guijas, V Magrioti, G Kokotos, ... The Journal of Immunology 192 (2), 752-762, 2014 | 161 | 2014 |
Phospholipase A2 inhibitors as potential therapeutic agents for the treatment of inflammatory diseases V Magrioti, G Kokotos Expert opinion on therapeutic patents 20 (1), 1-18, 2010 | 124 | 2010 |
Differing roles for members of the phospholipase A2 superfamily in experimental autoimmune encephalomyelitis A Kalyvas, C Baskakis, V Magrioti, V Constantinou-Kokotou, D Stephens, ... Brain 132 (5), 1221-1235, 2009 | 107 | 2009 |
Potent and Selective Fluoroketone Inhibitors of Group VIA Calcium-Independent Phospholipase A2 G Kokotos, YH Hsu, JE Burke, C Baskakis, CG Kokotos, V Magrioti, ... Journal of medicinal chemistry 53 (9), 3602-3610, 2010 | 106 | 2010 |
Structure−Activity Relationship of 2-Oxoamide Inhibition of Group IVA Cytosolic Phospholipase A2 and Group V Secreted Phospholipase A2 DA Six, E Barbayianni, V Loukas, V Constantinou-Kokotou, ... Journal of medicinal chemistry 50 (17), 4222-4235, 2007 | 98 | 2007 |
Synthesis of Polyfluoro Ketones for Selective Inhibition of Human Phospholipase A2 Enzymes C Baskakis, V Magrioti, N Cotton, D Stephens, V Constantinou-Kokotou, ... Journal of medicinal chemistry 51 (24), 8027-8037, 2008 | 83 | 2008 |
Autotaxin inhibitors: a patent review E Barbayianni, V Magrioti, P Moutevelis-Minakakis, G Kokotos Expert opinion on therapeutic patents 23 (9), 1123-1132, 2013 | 78 | 2013 |
Phospholipase A2 inhibitors for the treatment of inflammatory diseases: a patent review (2010 – present) V Magrioti, G Kokotos Expert Opinion on Therapeutic Patents 23 (3), 333-344, 2013 | 68 | 2013 |
Inhibition of Group IVA Cytosolic Phospholipase A2 by Thiazolyl Ketones in Vitro, ex Vivo, and in Vivo G Kokotos, AJ Feuerherm, E Barbayianni, I Shah, M Sæther, V Magrioti, ... Journal of medicinal chemistry 57 (18), 7523-7535, 2014 | 47 | 2014 |
Inhibition of Ca2+-Independent Phospholipase A2β (iPLA2β) Ameliorates Islet Infiltration and Incidence of Diabetes in NOD Mice RN Bone, Y Gai, V Magrioti, MG Kokotou, T Ali, X Lei, HM Tse, G Kokotos, ... Diabetes 64 (2), 541-554, 2015 | 46 | 2015 |
Characterization of FKGK18 as Inhibitor of Group VIA Ca2+-Independent Phospholipase A2 (iPLA2β): Candidate Drug for Preventing Beta-Cell Apoptosis and … T Ali, G Kokotos, V Magrioti, RN Bone, JA Mobley, W Hancock, ... PloS one 8 (8), e71748, 2013 | 46 | 2013 |
New potent and selective polyfluoroalkyl ketone inhibitors of GVIA calcium-independent phospholipase A2 V Magrioti, A Nikolaou, A Smyrniotou, I Shah, V Constantinou-Kokotou, ... Bioorganic & medicinal chemistry 21 (18), 5823-5829, 2013 | 42 | 2013 |
Inhibition of secreted phospholipases A2 by 2-oxoamides based on α-amino acids: Synthesis, in vitro evaluation and molecular docking calculations VD Mouchlis, V Magrioti, E Barbayianni, N Cermak, RC Oslund, ... Bioorganic & medicinal chemistry 19 (2), 735-743, 2011 | 39 | 2011 |
The Contribution of Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase A2s to Adrenic Acid Mobilization in Murine Macrophages P Monge, A Garrido, JM Rubio, V Magrioti, G Kokotos, MA Balboa, ... Biomolecules 10 (4), 542, 2020 | 37 | 2020 |
Structure–activity relationships of natural and non-natural amino acid-based amide and 2-oxoamide inhibitors of human phospholipase A2 enzymes G Antonopoulou, E Barbayianni, V Magrioti, N Cotton, D Stephens, ... Bioorganic & medicinal chemistry 16 (24), 10257-10269, 2008 | 36 | 2008 |
Synthetic inhibitors of group IVA and group VIA phospholipase A2 V Magrioti, G Kokotos Anti Inflammatory and Anti Allergy Agents in Medicinal Chemistry 5 (2), 189, 2006 | 29 | 2006 |
2-Oxoamide inhibitors of phospholipase A2 activity and cellular arachidonate release based on dipeptides and pseudodipeptides E Barbayianni, D Stephens, A Grkovich, V Magrioti, YH Hsu, P Dolatzas, ... Bioorganic & medicinal chemistry 17 (13), 4833-4843, 2009 | 25 | 2009 |
2-Oxoesters: A Novel Class of Potent and Selective Inhibitors of Cytosolic Group IVA Phospholipase A2 MG Kokotou, G Galiatsatou, V Magrioti, G Koutoulogenis, E Barbayianni, ... Scientific reports 7 (1), 7025, 2017 | 18 | 2017 |
Triacylglycerols Based on 2-(N-tert-Butoxycarbonylamino)oleic Acid Are Potent Inhibitors of Pancreatic Lipase V Magrioti, R Verger, V Constantinou-Kokotou Journal of medicinal chemistry 47 (2), 288-291, 2004 | 18 | 2004 |