Tumor-penetrating nanoparticles for enhanced anticancer activity of combined photodynamic and hypoxia-activated therapy Y Wang, Y Xie, J Li, ZH Peng, Y Sheinin, J Zhou, D Oupický ACS nano 11 (2), 2227-2238, 2017 | 445 | 2017 |
A versatile reducible polycation-based system for efficient delivery of a broad range of nucleic acids ML Read, S Singh, Z Ahmed, M Stevenson, SS Briggs, D Oupicky, ... Nucleic acids research 33 (9), e86-e86, 2005 | 419 | 2005 |
Temperature-controlled uptake and release in PNIPAM-modified porous silica nanoparticles YZ You, KK Kalebaila, SL Brock, D Oupicky Chemistry of Materials 20 (10), 3354-3359, 2008 | 392 | 2008 |
Polyelectrolyte vectors for gene delivery: influence of cationic polymer on biophysical properties of complexes formed with DNA MA Wolfert, PR Dash, O Nazarova, D Oupicky, LW Seymour, S Smart, ... Bioconjugate chemistry 10 (6), 993-1004, 1999 | 375 | 1999 |
Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation D Oupicky, M Ogris, KA Howard, PR Dash, K Ulbrich, LW Seymour Molecular Therapy 5 (4), 463-472, 2002 | 369 | 2002 |
Novel vectors for gene delivery formed by self-assembly of DNA with poly (L-lysine) grafted with hydrophilic polymers V Toncheva, MA Wolfert, PR Dash, D Oupicky, K Ulbrich, LW Seymour, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1380 (3), 354-368, 1998 | 369 | 1998 |
Laterally stabilized complexes of DNA with linear reducible polycations: strategy for triggered intracellular activation of DNA delivery vectors D Oupický, AL Parker, LW Seymour Journal of the American Chemical Society 124 (1), 8-9, 2002 | 286 | 2002 |
Physical properties and in vitro transfection efficiency of gene delivery vectors based on complexes of DNA with synthetic polycations T Reschel, Č Koňák, D Oupický, LW Seymour, K Ulbrich Journal of controlled release 81 (1-2), 201-217, 2002 | 249 | 2002 |
Decreased binding to proteins and cells of polymeric gene delivery vectors surface modified with a multivalent hydrophilic polymer and retargeting through attachment of transferrin PR Dash, ML Read, KD Fisher, KA Howard, M Wolfert, D Oupicky, V Subr, ... Journal of Biological Chemistry 275 (6), 3793-3802, 2000 | 233 | 2000 |
Recent advances in delivery of drug–nucleic acid combinations for cancer treatment J Li, Y Wang, Y Zhu, D Oupický Journal of controlled release 172 (2), 589-600, 2013 | 229 | 2013 |
Reducible poly (2-dimethylaminoethyl methacrylate): synthesis, cytotoxicity, and gene delivery activity YZ You, DS Manickam, QH Zhou, D Oupický Journal of Controlled Release 122 (3), 217-225, 2007 | 214 | 2007 |
Vectors based on reducible polycations facilitate intracellular release of nucleic acids ML Read, KH Bremner, D Oupický, NK Green, PF Searle, LW Seymour The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2003 | 211 | 2003 |
DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers D Oupický, Č Koňák, K Ulbrich, MA Wolfert, LW Seymour Journal of Controlled Release 65 (1-2), 149-171, 2000 | 199 | 2000 |
Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo D Oupický, RC Carlisle, LW Seymour Gene therapy 8 (9), 713-724, 2001 | 196 | 2001 |
Emerging roles of the CXCL12/CXCR4 axis in pancreatic cancer progression and therapy RL Sleightholm, BK Neilsen, J Li, MM Steele, RK Singh, MA Hollingsworth, ... Pharmacology & therapeutics 179, 158-170, 2017 | 157 | 2017 |
Modification of pLL/DNA complexes with a multivalent hydrophilic polymer permits folate‐mediated targeting in vitro and prolonged plasma circulation in vivo CM Ward, M Pechar, D Oupicky, K Ulbrich, LW Seymour The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2002 | 156 | 2002 |
Steric Stabilization of poly-l-Lysine/DNA Complexes by the Covalent Attachment of Semitelechelic poly[N-(2-Hydroxypropyl)methacrylamide] D Oupický, KA Howard, Č Koňák, PR Dash, K Ulbrich, LW Seymour Bioconjugate chemistry 11 (4), 492-501, 2000 | 149 | 2000 |
Enhanced gene and siRNA delivery by polycation-modified mesoporous silica nanoparticles loaded with chloroquine SR Bhattarai, E Muthuswamy, A Wani, M Brichacek, AL Castañeda, ... Pharmaceutical research 27, 2556-2568, 2010 | 143 | 2010 |
Targeting pulmonary tumor microenvironment with CXCR4-inhibiting nanocomplex to enhance anti–PD-L1 immunotherapy Z Li, Y Wang, Y Shen, C Qian, D Oupicky, M Sun Science advances 6 (20), eaaz9240, 2020 | 139 | 2020 |
Gene delivery in vitro and in vivo from bioreducible multilayered polyelectrolyte films of plasmid DNA J Blacklock, YZ You, QH Zhou, G Mao, D Oupický Biomaterials 30 (5), 939-950, 2009 | 138 | 2009 |