Diflavin oxidoreductases activate the bioreductive prodrug PR-104A under hypoxia CP Guise, MR Abbattista, SR Tipparaju, NK Lambie, J Su, D Li, ... Molecular pharmacology 81 (1), 31-40, 2012 | 77 | 2012 |
The 2-nitroimidazole EF5 is a biomarker for oxidoreductases that activate the bioreductive prodrug CEN-209 under hypoxia J Wang, A Foehrenbacher, J Su, R Patel, MP Hay, KO Hicks, WR Wilson Clinical Cancer Research 18 (6), 1684-1695, 2012 | 72 | 2012 |
Dual targeting of hypoxia and homologous recombination repair dysfunction in triple-negative breast cancer FW Hunter, HL Hsu, J Su, SM Pullen, WR Wilson, J Wang Molecular cancer therapeutics 13 (11), 2501-2514, 2014 | 50 | 2014 |
Zinc finger nuclease knock-out of NADPH: cytochrome P450 oxidoreductase (POR) in human tumor cell lines demonstrates that hypoxia-activated prodrugs differ in POR dependence J Su, Y Gu, FB Pruijn, JB Smaill, AV Patterson, CP Guise, WR Wilson Journal of Biological Chemistry 288 (52), 37138-37153, 2013 | 29 | 2013 |
FSL-61 is a 6-nitroquinolone fluorogenic probe for one-electron reductases in hypoxic cells J Su, CP Guise, WR Wilson Biochemical Journal 452 (1), 79-86, 2013 | 27 | 2013 |
Zinc finger nuclease mediated knockout of ADP-dependent glucokinase in cancer cell lines: effects on cell survival and mitochondrial oxidative metabolism S Richter, S Morrison, T Connor, J Su, CG Print, RS Ronimus, SL Mcgee, ... PLoS One 8 (6), e65267, 2013 | 18 | 2013 |
Print, CG, Ronimus, RS, McGee, SL and Wilson, WR (2013) Zinc finger nuclease mediated knockout of ADP-dependent glucokinase in cancer cell lines: effects on cell survival and … S Richter, S Morrison, T Connor, J Su PLoS One 8 (6), e65267, 0 | 11 | |
EF5 as a predictive biomarker for activation of the new hypoxia-targeting prodrug SN30000. J Wang, A Foehrenbacher, J Su, R Patel, MP Hay, KO Hicks, WR Wilson, ... Journal of Clinical Oncology 29 (15_suppl), e13597-e13597, 2011 | 5 | 2011 |
Identification of human oxidoreductases involved in the hypoxia-dependent activation of bioreductive prodrugs CP Guise, SR Tipparaju, MR Abbattista, GU Dachs, J Su, ... Cancer Research 70 (8_Supplement), 453-453, 2010 | 1 | 2010 |
Dissecting the role of NADPH: cytochrome P450 oxidoreductase in the activation of hypoxia-activated prodrugs using zinc finger nucleases J Su PhD Thesis-University of Auckland, 2013 | | 2013 |