Synthesis and antitumor activity of 1, 5-disubstituted 1, 2, 4-triazoles as cis-restricted combretastatin analogues R Romagnoli, PG Baraldi, O Cruz-Lopez, C Lopez Cara, MD Carrion, ... Journal of medicinal chemistry 53 (10), 4248-4258, 2010 | 194 | 2010 |
Synthesis and biological evaluation of 2-and 3-aminobenzo [b] thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization R Romagnoli, PG Baraldi, MD Carrion, CL Cara, D Preti, F Fruttarolo, ... Journal of medicinal chemistry 50 (9), 2273-2277, 2007 | 180 | 2007 |
Design, synthesis, and biological evaluation of thiophene analogues of chalcones R Romagnoli, PG Baraldi, MD Carrion, CL Cara, O Cruz-Lopez, D Preti, ... Bioorganic & medicinal chemistry 16 (10), 5367-5376, 2008 | 157 | 2008 |
Synthesis and biological evaluation of 1-methyl-2-(3′, 4′, 5′-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors R Romagnoli, PG Baraldi, T Sarkar, MD Carrion, CL Cara, O Cruz-Lopez, ... Journal of medicinal chemistry 51 (5), 1464-1468, 2008 | 119 | 2008 |
The P2X7 receptor as a therapeutic target R Romagnoli, PG Baraldi, O Cruz-Lopez, C Lopez-Cara, D Preti, ... Expert Opinion on Therapeutic Targets 12 (5), 647-661, 2008 | 105 | 2008 |
Design, synthesis and structure–activity relationship of 2-(3′, 4′, 5′-trimethoxybenzoyl)-benzo [b] furan derivatives as a novel class of inhibitors of tubulin polymerization R Romagnoli, PG Baraldi, MD Carrion, CL Cara, O Cruz-Lopez, ... Bioorganic & medicinal chemistry 17 (19), 6862-6871, 2009 | 90 | 2009 |
Hybrid α-bromoacryloylamido chalcones. Design, synthesis and biological evaluation R Romagnoli, PG Baraldi, MD Carrion, O Cruz-Lopez, CL Cara, ... Bioorganic & Medicinal Chemistry Letters 19 (7), 2022-2028, 2009 | 72 | 2009 |
Synthesis and biological evaluation of 2-(3 ‘, 4 ‘, 5 ‘-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors R Romagnoli, PG Baraldi, V Remusat, MD Carrion, CL Cara, D Preti, ... Journal of medicinal chemistry 49 (21), 6425-6428, 2006 | 72 | 2006 |
2-Arylamino-4-amino-5-aroylthiazoles.“One-pot” synthesis and biological evaluation of a new class of inhibitors of tubulin polymerization R Romagnoli, PG Baraldi, MD Carrion, O Cruz-Lopez, C Lopez Cara, ... Journal of medicinal chemistry 52 (17), 5551-5555, 2009 | 68 | 2009 |
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents R Romagnoli, PG Baraldi, C Lopez-Cara, D Preti, M Aghazadeh Tabrizi, ... Journal of medicinal chemistry 56 (22), 9296-9309, 2013 | 66 | 2013 |
Kynurenamines as neural nitric oxide synthase inhibitors A Entrena, ME Camacho, MD Carrión, LC López-Cara, G Velasco, J León, ... Journal of medicinal chemistry 48 (26), 8174-8181, 2005 | 66 | 2005 |
Synthesis and biological evaluation of 2-(3′, 4′, 5′-trimethoxybenzoyl)-3-N, N-dimethylamino benzo [b] furan derivatives as inhibitors of tubulin polymerization R Romagnoli, PG Baraldi, T Sarkar, MD Carrion, O Cruz-Lopez, CL Cara, ... Bioorganic & medicinal chemistry 16 (18), 8419-8426, 2008 | 65 | 2008 |
Design, Synthesis, in Vitro and in Vivo Anticancer and Antiangiogenic Activity of Novel 3-Arylamino Benzofuran Derivatives Targeting the Colchicine Site on Tubulin GV R. Romagnoli, P. G.Baraldi, M. Kimatrai Salvador, F. Prencipe, L.C. Lopez ... Journal of Medicinal Chemistry 58 (7), 3209-3222, 2015 | 62 | 2015 |
In silico pharmacology for a multidisciplinary drug discovery process SS Ortega, LCL Cara, MK Salvador Drug metabolism and drug interactions 27 (4), 199-207, 2012 | 61 | 2012 |
Pyrazoles and pyrazolines as neural and inducible nitric oxide synthase (nNOS and iNOS) potential inhibitors (III) MD Carrión, LCL Cara, ME Camacho, V Tapias, G Escames, ... European journal of medicinal chemistry 43 (11), 2579-2591, 2008 | 61 | 2008 |
Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N-(substituted) piperazin-1-yl] thiophenes as potent allosteric enhancers of the A1 adenosine receptor R Romagnoli, PG Baraldi, MD Carrion, CL Cara, O Cruz-Lopez, ... Journal of medicinal chemistry 51 (18), 5875-5879, 2008 | 56 | 2008 |
Synthesis and biological evaluation of 2-(3′, 4′, 5′-trimethoxybenzoyl)-3-aryl/arylaminobenzo [b] thiophene derivatives as a novel class of antiproliferative agents R Romagnoli, PG Baraldi, CL Cara, E Hamel, G Basso, R Bortolozzi, ... European journal of medicinal chemistry 45 (12), 5781-5791, 2010 | 53 | 2010 |
Allosteric enhancers for A1 adenosine receptor. PG Baraldi, MA Iaconinoto, AR Moorman, MD Carrion, CL Cara, D Preti, ... Mini reviews in medicinal chemistry 7 (6), 559-569, 2007 | 51 | 2007 |
New (RS)-benzoxazepin-purines with antitumour activity: the chiral switch from (RS)-2, 6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1, 2, 3, 5-tetrahydro-4, 1-benzoxazepin-3-yl]-9H … LC López-Cara, A Conejo-García, JA Marchal, G Macchione, ... European journal of medicinal chemistry 46 (1), 249-258, 2011 | 50 | 2011 |
Design, synthesis and biological evaluation of 3, 5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents R Romagnoli, PG Baraldi, C Lopez-Cara, MK Salvador, D Preti, ... Bioorganic & medicinal chemistry 22 (18), 5097-5109, 2014 | 46 | 2014 |