| Mandelate racemase in pieces: effective concentrations of enzyme functional groups in the transition state SL Bearne, R Wolfenden Biochemistry 36 (7), 1646-1656, 1997 | 81 | 1997 |
| Proteomic investigation of amino acid catabolism in the indigenous gut anaerobe Fusobacterium varium J Potrykus, RL White, SL Bearne Proteomics 8 (13), 2691-2703, 2008 | 72 | 2008 |
| Inhibition of Escherichia coli CTP synthase by glutamate γ-semialdehyde and the role of the allosteric effector GTP in glutamine hydrolysis SL Bearne, O Hekmat, JE MacDONNELL Biochemical Journal 356 (1), 223-232, 2001 | 70 | 2001 |
| Inhibition of Escherichia coliGlucosamine-6-phosphate Synthase by Reactive Intermediate Analogues: THE ROLE OF THE 2-AMINO FUNCTION IN CATALYSIS SL Bearne, C Blouin Journal of Biological Chemistry 275 (1), 135-140, 2000 | 70 | 2000 |
| Glutamate. gamma.-Semialdehyde as a Natural Transition State Analog Inhibitor of Escherichia coli Glucosamine-6-phosphate Synthase SL Bearne, R Wolfenden Biochemistry 34 (36), 11515-11520, 1995 | 62 | 1995 |
| Kinetics and thermodynamics of mandelate racemase catalysis M St. Maurice, SL Bearne Biochemistry 41 (12), 4048-4058, 2002 | 55 | 2002 |
| Oxidative stress response in the opportunistic oral pathogen Fusobacterium nucleatum CH Steeves, J Potrykus, DA Barnett, SL Bearne Proteomics 11 (10), 2027-2037, 2011 | 49 | 2011 |
| Hydrophobic nature of the active site of mandelate racemase M St. Maurice, SL Bearne Biochemistry 43 (9), 2524-2532, 2004 | 49 | 2004 |
| Dicarboxylic acid bis (methyl phosphates): anionic biomimetic crosslinking reagents R Kluger, AS Grant, SL Bearne, MR Trachsel The Journal of Organic Chemistry 55 (9), 2864-2868, 1990 | 49 | 1990 |
| Reaction intermediate analogues for mandelate racemase: interaction between Asn 197 and the α-hydroxyl of the substrate promotes catalysis M St. Maurice, SL Bearne Biochemistry 39 (44), 13324-13335, 2000 | 48 | 2000 |
| Active site-directed inactivation of Escherichia coli glucosamine-6-phosphate synthase: determination of the fructose 6-phosphate binding constant using a carbohydrate-based … SL Bearne Journal of Biological Chemistry 271 (6), 3052-3057, 1996 | 45 | 1996 |
| Proteomic investigation of glucose metabolism in the butyrate‐producing gut anaerobe Fusobacterium varium J Potrykus, B Mahaney, RL White, SL Bearne Proteomics 7 (11), 1839-1853, 2007 | 43 | 2007 |
| Purification of recombinant mandelate racemase: improved catalytic activity A Narmandakh, SL Bearne Protein expression and purification 69 (1), 39-46, 2010 | 41 | 2010 |
| Aspartate-107 and leucine-109 facilitate efficient coupling of glutamine hydrolysis to CTP synthesis by Escherichia coli CTP synthase A Iyengar, SL Bearne Biochemical Journal 369 (3), 497-507, 2003 | 41 | 2003 |
| Enzymic hydration of an olefin: the burden borne by fumarase SL Bearne, R Wolfenden Journal of the American Chemical Society 117 (37), 9588-9589, 1995 | 39 | 1995 |
| Inhibition of E. coli CTP synthase by the “positive” allosteric effector GTP JE MacDonnell, FA Lunn, SL Bearne Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1699 (1-2), 213-220, 2004 | 38 | 2004 |
| Exploring the potent inhibition of CTP synthase by gemcitabine‐5′‐triphosphate GD McCluskey, S Mohamady, SD Taylor, SL Bearne Chembiochem 17 (23), 2240-2249, 2016 | 36 | 2016 |
| Structural requirements for the activation of Escherichia coli CTP synthase by the allosteric effector GTP are stringent, but requirements for inhibition are lax FA Lunn, JE MacDonnell, SL Bearne Journal of Biological Chemistry 283 (4), 2010-2020, 2008 | 36 | 2008 |
| Perturbing the hydrophobic pocket of mandelate racemase to probe phenyl motion during catalysis F Siddiqi, JR Bourque, H Jiang, M Gardner, M St. Maurice, C Blouin, ... Biochemistry 44 (25), 9013-9021, 2005 | 36 | 2005 |
| Structure of mandelate racemase with bound intermediate analogues benzohydroxamate and cupferron AD Lietzan, M Nagar, EA Pellmann, JR Bourque, SL Bearne, ... Biochemistry 51 (6), 1160-1170, 2012 | 34 | 2012 |
