Highly multiplexed simultaneous detection of RNAs and proteins in single cells AP Frei, FA Bava, ER Zunder, EWY Hsieh, SY Chen, GP Nolan, ... Nature methods 13 (3), 269-275, 2016 | 343 | 2016 |
Unifying mechanism for different fibrotic diseases G Wernig, SY Chen, L Cui, C Van Neste, JM Tsai, N Kambham, H Vogel, ... Proceedings of the National Academy of Sciences 114 (18), 4757-4762, 2017 | 208 | 2017 |
Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis JM Churko, P Garg, B Treutlein, M Venkatasubramanian, H Wu, J Lee, ... Nature communications 9 (1), 4906, 2018 | 183 | 2018 |
Commonly occurring cell subsets in high-grade serous ovarian tumors identified by single-cell mass cytometry VD Gonzalez, N Samusik, TJ Chen, ES Savig, N Aghaeepour, DA Quigley, ... Cell reports 22 (7), 1875-1888, 2018 | 92 | 2018 |
Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity L Cui, SY Chen, T Lerbs, JW Lee, P Domizi, S Gordon, Y Kim, G Nolan, ... Nature Communications 11 (1), 2795, 2020 | 89 | 2020 |
Complex mammalian-like haematopoietic system found in a colonial chordate B Rosental, M Kowarsky, J Seita, DM Corey, KJ Ishizuka, KJ Palmeri, ... Nature 564 (7736), 425-429, 2018 | 77 | 2018 |
Disrupted-in-Schizophrenia 1–mediated axon guidance involves TRIO-RAC-PAK small GTPase pathway signaling SY Chen, PH Huang, HJ Cheng Proceedings of the National Academy of Sciences 108 (14), 5861-5866, 2011 | 72 | 2011 |
A human multi-lineage hepatic organoid model for liver fibrosis Y Guan, A Enejder, M Wang, Z Fang, L Cui, SY Chen, J Wang, Y Tan, ... Nature communications 12 (1), 6138, 2021 | 71 | 2021 |
Upregulation of human endogenous retrovirus-K is linked to immunity and inflammation in pulmonary arterial hypertension T Saito, K Miyagawa, SY Chen, R Tamosiuniene, L Wang, O Sharpe, ... Circulation 136 (20), 1920-1935, 2017 | 60 | 2017 |
Mass cytometry as a platform for the discovery of cellular biomarkers to guide effective rheumatic disease therapy N Nair, HE Mei, SY Chen, M Hale, GP Nolan, HT Maecker, M Genovese, ... Arthritis research & therapy 17, 1-9, 2015 | 57 | 2015 |
Spatial multi-omics analyses of the tumor immune microenvironment WC Hsieh, BR Budiarto, YF Wang, CY Lin, MC Gwo, DK So, YS Tzeng, ... Journal of Biomedical Science 29 (1), 96, 2022 | 55 | 2022 |
High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment VD Gonzalez, YW Huang, A Delgado-Gonzalez, SY Chen, K Donoso, ... Cell reports 36 (9), 2021 | 52 | 2021 |
Atomic mass tag of bismuth‐209 for increasing the immunoassay multiplexing capacity of mass cytometry G Han, SY Chen, VD Gonzalez, ER Zunder, WJ Fantl, GP Nolan Cytometry Part A 91 (12), 1150-1163, 2017 | 50 | 2017 |
Subcellular localization of biomolecules and drug distribution by high-definition ion beam imaging X Rovira-Clavé, S Jiang, Y Bai, B Zhu, G Barlow, S Bhate, AF Coskun, ... Nature Communications 12 (1), 4628, 2021 | 46 | 2021 |
Functions of axon guidance molecules in synapse formation SY Chen, HJ Cheng Current opinion in neurobiology 19 (5), 471-478, 2009 | 45 | 2009 |
NK cell receptor and ligand composition influences the clearance of SARS-CoV-2 WC Hsieh, EY Lai, YT Liu, YF Wang, YS Tzeng, L Cui, YJ Lai, HC Huang, ... The Journal of Clinical Investigation 131 (21), 2021 | 31 | 2021 |
In silico modeling identifies CD45 as a regulator of IL-2 synergy in the NKG2D-mediated activation of immature human NK cells S Mukherjee, H Jensen, W Stewart, D Stewart, WC Ray, SY Chen, ... Science signaling 10 (485), eaai9062, 2017 | 31 | 2017 |
NKG2D ligand expression in Crohn's disease and NKG2D-dependent stimulation of CD8+ T cell migration K Vadstrup, ED Galsgaard, H Jensen, LL Lanier, JC Ryan, SY Chen, ... Experimental and molecular pathology 103 (1), 56-70, 2017 | 25 | 2017 |
Innate immune cell activation causes lung fibrosis in a humanized model of long COVID L Cui, Z Fang, CM De Souza, T Lerbs, Y Guan, I Li, V Charu, SY Chen, ... Proceedings of the National Academy of Sciences 120 (10), e2217199120, 2023 | 21 | 2023 |
Epigenetic modulation of immune synaptic-cytoskeletal networks potentiates γδ T cell-mediated cytotoxicity in lung cancer RR Weng, HH Lu, CT Lin, CC Fan, RS Lin, TC Huang, SY Lin, YJ Huang, ... Nature communications 12 (1), 2163, 2021 | 21 | 2021 |