ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response J Heijmans, JFL de Jeude, BK Koo, SL Rosekrans, MCB Wielenga, ... Cell reports 3 (4), 1128-1139, 2013 | 269 | 2013 |
Bone morphogenetic protein signalling in colorectal cancer JC Hardwick, LL Kodach, GJ Offerhaus, GR Van Den Brink Nature Reviews Cancer 8 (10), 806-812, 2008 | 260 | 2008 |
Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells LL Kodach, CL Bos, N Durán, MP Peppelenbosch, CV Ferreira, ... Carcinogenesis 27 (3), 508-516, 2006 | 205 | 2006 |
The bone morphogenetic protein pathway is inactivated in the majority of sporadic colorectal cancers LL Kodach, E Wiercinska, NFCC De Miranda, SA Bleuming, AR Musler, ... Gastroenterology 134 (5), 1332-1341. e3, 2008 | 203 | 2008 |
Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK PW Voorneveld, LL Kodach, RJ Jacobs, N Liv, AC Zonnevylle, ... Gastroenterology 147 (1), 196-208. e13, 2014 | 185 | 2014 |
Effect of aspirin on the Wnt/β-catenin pathway is mediated via protein phosphatase 2A CL Bos, LL Kodach, GR van den Brink, SH Diks, MM van Santen, ... Oncogene 25 (49), 6447-6456, 2006 | 183 | 2006 |
Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell ‘stemness’ via the bone morphogenetic … LL Kodach, RJ Jacobs, PW Voorneveld, ME Wildenberg, HW Verspaget, ... Gut 60 (11), 1544-1553, 2011 | 162 | 2011 |
Bone morphogenetic protein signaling suppresses tumorigenesis at gastric epithelial transition zones in mice SA Bleuming, XC He, LL Kodach, JC Hardwick, FA Koopman, ... Cancer research 67 (17), 8149-8155, 2007 | 144 | 2007 |
The bone morphogenetic protein pathway is active in human colon adenomas and inactivated in colorectal cancer LL Kodach, SA Bleuming, AR Musler, MP Peppelenbosch, DW Hommes, ... Cancer: Interdisciplinary International Journal of the American Cancer …, 2008 | 107 | 2008 |
The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer LL Kodach, RJ Jacobs, J Heijmans, CJM van Noesel, AMJ Langers, ... Carcinogenesis 31 (9), 1567-1575, 2010 | 106 | 2010 |
The effect of statins in colorectal cancer is mediated through the bone morphogenetic protein pathway LL Kodach, SA Bleuming, MP Peppelenbosch, DW Hommes, ... Gastroenterology 133 (4), 1272-1281, 2007 | 105 | 2007 |
The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC PW Voorneveld, LL Kodach, RJ Jacobs, CJM Van Noesel, ... British journal of cancer 112 (1), 122-130, 2015 | 91 | 2015 |
Statin use after diagnosis of colon cancer and patient survival PW Voorneveld, MS Reimers, E Bastiaannet, RJ Jacobs, R van Eijk, ... Gastroenterology 153 (2), 470-479. e4, 2017 | 85 | 2017 |
SMAD4 exerts a tumor-promoting role in hepatocellular carcinoma PY Hernanda, K Chen, AM Das, K Sideras, W Wang, J Li, W Cao, ... Oncogene 34 (39), 5055-5068, 2015 | 71 | 2015 |
A promising action of riboflavin as a mediator of leukaemia cell death ACS De Souza, L Kodach, FR Gadelha, CL Bos, ADM Cavagis, ... Apoptosis 11, 1761-1771, 2006 | 68 | 2006 |
A meta-analysis of SMAD4 immunohistochemistry as a prognostic marker in colorectal cancer PW Voorneveld, RJ Jacobs, LL Kodach, JCH Hardwick Translational oncology 8 (1), 18-24, 2015 | 52 | 2015 |
Altered bone morphogenetic protein signalling in the Helicobacter pylori‐infected stomach SA Bleuming, LL Kodach, MJ Garcia Leon, DJ Richel, MP Peppelenbosch, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2006 | 51 | 2006 |
Low molecular weight protein tyrosine phosphatase (LMWPTP) upregulation mediates malignant potential in colorectal cancer E Hoekstra, LL Kodach, AM Das, RR Ruela-de-Sousa, CV Ferreira, ... Oncotarget 6 (10), 8300, 2015 | 39 | 2015 |
Reduced expression of bone morphogenetic protein receptor IA in pancreatic cancer is associated with a poor prognosis PW Voorneveld, V Stache, RJ Jacobs, E Smolders, AI Sitters, A Liesker, ... British journal of cancer 109 (7), 1805-1812, 2013 | 35 | 2013 |
Gastroscopic surveillance with targeted biopsies compared with random biopsies in CDH1 mutation carriers JM van Dieren, LL Kodach, P den Hartog, LE van der Kolk, K Sikorska, ... Endoscopy 52 (10), 839-846, 2020 | 34 | 2020 |