Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles A Subramanian, P Tamayo, VK Mootha, S Mukherjee, BL Ebert, ... Proceedings of the National Academy of Sciences 102 (43), 15545-15550, 2005 | 45696 | 2005 |
MicroRNA expression profiles classify human cancers J Lu, G Getz, EA Miska, E Alvarez-Saavedra, J Lamb, D Peck, ... nature 435 (7043), 834-838, 2005 | 11862 | 2005 |
Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel H Döhner, E Estey, D Grimwade, S Amadori, FR Appelbaum, T Büchner, ... Blood, The Journal of the American Society of Hematology 129 (4), 424-447, 2017 | 5826 | 2017 |
Genome-scale CRISPR-Cas9 knockout screening in human cells O Shalem, NE Sanjana, E Hartenian, X Shi, DA Scott, TS Mikkelsen, ... Science 343 (6166), 84-87, 2014 | 5573 | 2014 |
Age-related clonal hematopoiesis associated with adverse outcomes S Jaiswal, P Fontanillas, J Flannick, A Manning, PV Grauman, BG Mar, ... New England Journal of Medicine 371 (26), 2488-2498, 2014 | 4377 | 2014 |
The landscape of somatic copy-number alteration across human cancers R Beroukhim, CH Mermel, D Porter, G Wei, S Raychaudhuri, J Donovan, ... Nature 463 (7283), 899-905, 2010 | 4261 | 2010 |
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis RL Levine, M Wadleigh, J Cools, BL Ebert, G Wernig, BJP Huntly, ... Cancer cell 7 (4), 387-397, 2005 | 3841 | 2005 |
Clonal hematopoiesis and risk of atherosclerotic cardiovascular disease S Jaiswal, P Natarajan, AJ Silver, CJ Gibson, AG Bick, E Shvartz, ... New England Journal of Medicine 377 (2), 111-121, 2017 | 2091 | 2017 |
Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes DP Steensma, R Bejar, S Jaiswal, RC Lindsley, MA Sekeres, ... Blood, The Journal of the American Society of Hematology 126 (1), 9-16, 2015 | 1937 | 2015 |
Clinical effect of point mutations in myelodysplastic syndromes R Bejar, K Stevenson, O Abdel-Wahab, N Galili, B Nilsson, ... New England Journal of Medicine 364 (26), 2496-2506, 2011 | 1925 | 2011 |
MPLW515L Is a Novel Somatic Activating Mutation in Myelofibrosis with Myeloid Metaplasia Y Pikman, BH Lee, T Mercher, E McDowell, BL Ebert, M Gozo, A Cuker, ... PLoS medicine 3 (7), e270, 2006 | 1771 | 2006 |
Rational design of highly active sgRNAs for CRISPR-Cas9–mediated gene inactivation JG Doench, E Hartenian, DB Graham, Z Tothova, M Hegde, I Smith, ... Nature biotechnology 32 (12), 1262-1267, 2014 | 1767 | 2014 |
Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells J Krönke, ND Udeshi, A Narla, P Grauman, SN Hurst, M McConkey, ... Science 343 (6168), 301-305, 2014 | 1685 | 2014 |
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia MHGP Raaijmakers, S Mukherjee, S Guo, S Zhang, T Kobayashi, ... Nature 464 (7290), 852-857, 2010 | 1264 | 2010 |
International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data DA Arber, A Orazi, RP Hasserjian, MJ Borowitz, KR Calvo, HM Kvasnicka, ... Blood, The Journal of the American Society of Hematology 140 (11), 1200-1228, 2022 | 1224 | 2022 |
Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN H Döhner, AH Wei, FR Appelbaum, C Craddock, CD DiNardo, H Dombret, ... Blood, The Journal of the American Society of Hematology 140 (12), 1345-1377, 2022 | 1203 | 2022 |
Stem cell gene expression programs influence clinical outcome in human leukemia K Eppert, K Takenaka, ER Lechman, L Waldron, B Nilsson, P Van Galen, ... Nature medicine 17 (9), 1086-1093, 2011 | 1164 | 2011 |
Identification of RPS14 as a 5q- syndrome gene by RNA interference screen BL Ebert, J Pretz, J Bosco, CY Chang, P Tamayo, N Galili, A Raza, ... Nature 451 (7176), 335-339, 2008 | 1088 | 2008 |
Densely interconnected transcriptional circuits control cell states in human hematopoiesis N Novershtern, A Subramanian, LN Lawton, RH Mak, WN Haining, ... Cell 144 (2), 296-309, 2011 | 1056 | 2011 |
Acute myeloid leukemia ontogeny is defined by distinct somatic mutations RC Lindsley, BG Mar, E Mazzola, PV Grauman, S Shareef, SL Allen, ... Blood, The Journal of the American Society of Hematology 125 (9), 1367-1376, 2015 | 985 | 2015 |