受强制性开放获取政策约束的文章 - Martin Noble了解详情
无法在其他位置公开访问的文章：8 篇
Analysis of chemical shift changes reveals the binding modes of isoindolinone inhibitors of the MDM2-p53 interaction
C Riedinger, JA Endicott, SJ Kemp, LA Smyth, A Watson, E Valeur, ...
Journal of the American Chemical Society 130 (47), 16038-16044, 2008
强制性开放获取政策： Cancer Research UK
The structure of an MDM2–Nutlin-3a complex solved by the use of a validated MDM2 surface-entropy reduction mutant
B Anil, C Riedinger, JA Endicott, MEM Noble
Acta Crystallographica Section D: Biological Crystallography 69 (8), 1358-1366, 2013
强制性开放获取政策： UK Medical Research Council
Structure-based design of potent and orally active isoindolinone inhibitors of MDM2-p53 protein–protein interaction
G Chessari, IR Hardcastle, JS Ahn, B Anil, E Anscombe, RH Bawn, ...
Journal of Medicinal Chemistry 64 (7), 4071-4088, 2021
强制性开放获取政策： Cancer Research UK, National Institute for Health Research, UK
Plasticity of the TSG-6 HA-binding loop and mobility in the TSG-6-HA complex revealed by NMR and X-ray crystallography
VA Higman, CD Blundell, DJ Mahoney, C Redfield, MEM Noble, AJ Day
Journal of molecular biology 371 (3), 669-684, 2007
强制性开放获取政策： Versus Arthritis, UK
Understanding Small‐Molecule Binding to MDM2: Insights into Structural Effects of Isoindolinone Inhibitors from NMR Spectroscopy
C Riedinger, ME Noble, DJ Wright, F Mulks, IR Hardcastle, JA Endicott, ...
Chemical biology & drug design 77 (5), 301-308, 2011
强制性开放获取政策： Cancer Research UK
8-Substituted O6-Cyclohexylmethylguanine CDK2 Inhibitors: Using Structure-Based Inhibitor Design to Optimize an Alternative Binding Mode
B Carbain, DJ Paterson, E Anscombe, AJ Campbell, C Cano, A Echalier, ...
Journal of Medicinal Chemistry 57 (1), 56-70, 2014
强制性开放获取政策： Cancer Research UK, UK Medical Research Council
An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase
I Al-Khawaldeh, MJ Al Yasiri, GG Aldred, C Basmadjian, C Bordoni, ...
Journal of medicinal chemistry 64 (14), 10001-10018, 2021
强制性开放获取政策： Cancer Research UK
Crystallographic fragment screening in academic cancer drug discovery
MP Martin, JA Endicott, MEM Noble, NJ Tatum
Methods in enzymology 690, 211-234, 2023
强制性开放获取政策： Cancer Research UK, UK Medical Research Council
可在其他位置公开访问的文章：43 篇
Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease
A Douangamath, D Fearon, P Gehrtz, T Krojer, P Lukacik, CD Owen, ...
Nature communications 11 (1), 5047, 2020
强制性开放获取政策： Genome Canada, Hungarian Scientific Research Fund, Cancer Research UK, UK …
CCP4i2: the new graphical user interface to the CCP4 program suite
L Potterton, J Agirre, C Ballard, K Cowtan, E Dodson, PR Evans, ...
Acta Crystallographica Section D: Structural Biology 74 (2), 68-84, 2018
强制性开放获取政策： Netherlands Organisation for Scientific Research, UK Biotechnology and …
Structures of the Cd44–hyaluronan complex provide insight into a fundamental carbohydrate-protein interaction
S Banerji, AJ Wright, M Noble, DJ Mahoney, ID Campbell, AJ Day, ...
Nature structural & molecular biology 14 (3), 234-239, 2007
强制性开放获取政策： Versus Arthritis, UK
The CCP4 suite: integrative software for macromolecular crystallography
J Agirre, M Atanasova, H Bagdonas, CB Ballard, A Baslé, ...
Acta Crystallographica Section D: Structural Biology 79 (6), 449-461, 2023
强制性开放获取政策： German Research Foundation, European Molecular Biology Laboratory …
CDK1 structures reveal conserved and unique features of the essential cell cycle CDK
NR Brown, S Korolchuk, MP Martin, WA Stanley, R Moukhametzianov, ...
Nature communications 6 (1), 1-12, 2015
强制性开放获取政策： UK Medical Research Council
Isoindolinone inhibitors of the murine double minute 2 (MDM2)-p53 protein− protein interaction: structure− activity studies leading to improved potency
IR Hardcastle, J Liu, E Valeur, A Watson, SU Ahmed, TJ Blackburn, ...
Journal of medicinal chemistry 54 (5), 1233-1243, 2011
强制性开放获取政策： Cancer Research UK
The structure of CDK4/cyclin D3 has implications for models of CDK activation
T Takaki, A Echalier, NR Brown, T Hunt, JA Endicott, MEM Noble
Proceedings of the National Academy of Sciences 106 (11), 4171-4176, 2009
强制性开放获取政策： Cancer Research UK
Substituted 4-(thiazol-5-yl)-2-(phenylamino) pyrimidines are highly active CDK9 inhibitors: synthesis, X-ray crystal structures, structure–activity relationship, and anticancer …
H Shao, S Shi, S Huang, AJ Hole, AY Abbas, S Baumli, X Liu, F Lam, ...
Journal of medicinal chemistry 56 (3), 640-659, 2013
强制性开放获取政策： Cancer Research UK
Differences in the conformational energy landscape of CDK1 and CDK2 suggest a mechanism for achieving selective CDK inhibition
DJ Wood, S Korolchuk, NJ Tatum, LZ Wang, JA Endicott, MEM Noble, ...
Cell chemical biology 26 (1), 121-130. e5, 2019
强制性开放获取政策： Cancer Research UK, UK Medical Research Council
Identification and Characterization of an Irreversible Inhibitor of CDK2
E Anscombe, E Meschini, R Mora-Vidal, MP Martin, D Staunton, ...
Chemistry & biology 22 (9), 1159-1164, 2015
强制性开放获取政策： Swedish Research Council, Cancer Research UK, UK Medical Research Council
Cyclin-dependent kinase (CDK) inhibitors: structure–activity relationships and insights into the CDK-2 selectivity of 6-substituted 2-arylaminopurines
CR Coxon, E Anscombe, SJ Harnor, MP Martin, B Carbain, BT Golding, ...
Journal of medicinal chemistry 60 (5), 1746-1767, 2017
强制性开放获取政策： Cancer Research UK, UK Medical Research Council
FragLites—minimal, halogenated fragments displaying pharmacophore doublets. An efficient approach to druggability assessment and hit generation
DJ Wood, JD Lopez-Fernandez, LE Knight, I Al-Khawaldeh, C Gai, S Lin, ...
Journal of Medicinal Chemistry 62 (7), 3741-3752, 2019
强制性开放获取政策： Cancer Research UK, UK Medical Research Council
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