| Atypical activation of the G protein Gαq by the oncogenic mutation Q209P M Maziarz, A Leyme, A Marivin, A Luebbers, PP Patel, Z Chen, ... Journal of Biological Chemistry 293 (51), 19586-19599, 2018 | 36 | 2018 |
| A biochemical and genetic discovery pipeline identifies PLCδ4b as a nonreceptor activator of heterotrimeric G-proteins M Maziarz, S Broselid, V DiGiacomo, JC Park, A Luebbers, ... Journal of Biological Chemistry 293 (44), 16964-16983, 2018 | 20 | 2018 |
| Optogenetic activation of heterotrimeric G-proteins by LOV2GIVe, a rationally engineered modular protein M Garcia-Marcos, K Parag-Sharma, A Marivin, M Maziarz, A Luebbers, ... Elife 9, e60155, 2020 | 18 | 2020 |
| Probing the mutational landscape of regulators of G protein signaling proteins in cancer V DiGiacomo, M Maziarz, A Luebbers, JM Norris, P Laksono, ... Science signaling 13 (617), eaax8620, 2020 | 18 | 2020 |
| Fine-tuning GPCR-mediated neuromodulation by biasing signaling through different G protein subunits JC Park, A Luebbers, M Dao, A Semeano, AM Nguyen, ... Molecular cell 83 (14), 2540-2558. e12, 2023 | 14 | 2023 |
| Direct interrogation of context-dependent GPCR activity with a universal biosensor platform R Janicot, M Maziarz, JC Park, J Zhao, A Luebbers, E Green, CE Philibert, ... Cell 187 (6), 1527-1546. e25, 2024 | 10 | 2024 |
| Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer J Zhao, V DiGiacomo, M Ferreras-Gutierrez, S Dastjerdi, ... Proceedings of the National Academy of Sciences 120 (18), e2213140120, 2023 | 7 | 2023 |
| Dissecting the molecular basis for the modulation of neurotransmitter GPCR signaling by GINIP A Luebbers, AJ Gonzalez-Hernandez, M Zhou, SJ Eyles, J Levitz, ... Structure 32 (1), 47-59. e7, 2024 | 6 | 2024 |
| Gαs inhibitor peptide probes for the spatiotemporal interrogation of signaling J Zhao, A Luebbers, S Savransky, M Maziarz, JP Vilardaga, ... Journal of Pharmacology and Experimental Therapeutics 389 (S3), 2024 | | 2024 |
| Direct detection of endogenous Gαi activity in cells with a sensitive conformational biosensor A Luebbers, R Janicot, J Zhao, CE Philibert, M Garcia-Marcos bioRxiv, 2024.08. 21.609006, 2024 | | 2024 |
| Dissecting the molecular basis of neurotransmitter signaling modulation by GINIP A Luebbers Boston University, 2024 | | 2024 |
| Small-molecule targeting of GPCR-independent non-canonical G protein signaling inhibits cancer progression J Zhao, V DiGiacomo, M Ferreras-Gutierrez, S Dastjerdi, AI de Opakua, ... bioRxiv, 2023.02. 18.529092, 2023 | | 2023 |
| Identification of Peptide Sequence Served as Genetically-Encoded or Chemical Probes to Inhibit Gαs in Cells J Zhao, A Luebbers, M Maziarz, M Garcia-Marcos Journal of Biological Chemistry 299 (3), 104348, 2023 | | 2023 |
| Dissecting the molecular basis for the modulation of neurotransmitter GPCR signaling by a Gαi-binding protein A Luebbers, M Zhou, S Eyles, M Garcia-Marcos Journal of Biological Chemistry 299 (3), 104387, 2023 | | 2023 |
| Identification of Peptide Inhibitors of Gαs that Block its Effector Binding Site A Luebbers, M Maziarz, M Garcia‐Marcos The FASEB Journal 36, 2022 | | 2022 |
