Cell-surface proteoglycans as molecular portals for cationic peptide and polymer entry into cells GMK Poon, J Gariepy Biochemical Society Transactions 35 (4), 788-793, 2007 | 286 | 2007 |
PU. 1 controls fibroblast polarization and tissue fibrosis T Wohlfahrt, S Rauber, S Uebe, M Luber, A Soare, A Ekici, S Weber, ... Nature 566 (7744), 344-349, 2019 | 151 | 2019 |
ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma P Mao, AJ Brown, S Esaki, S Lockwood, GMK Poon, MJ Smerdon, ... Nature communications 9 (1), 2626, 2018 | 132 | 2018 |
Prodrug applications for targeted cancer therapy I Giang, EL Boland, GMK Poon The AAPS journal 16, 899-913, 2014 | 118 | 2014 |
Pharmacological inhibition of the transcription factor PU. 1 in leukemia I Antony-Debré, A Paul, J Leite, K Mitchell, HM Kim, LA Carvajal, ... The Journal of clinical investigation 127 (12), 4297-4313, 2017 | 111 | 2017 |
DNA mismatches reveal conformational penalties in protein–DNA recognition A Afek, H Shi, A Rangadurai, H Sahay, A Senitzki, S Xhani, M Fang, ... Nature 587 (7833), 291-296, 2020 | 94 | 2020 |
The catalytic subunit of Shiga-like toxin 1 interacts with ribosomal stalk proteins and is inhibited by their conserved C-terminal domain AJ McCluskey, GMK Poon, E Bolewska-Pedyczak, T Srikumar, SM Jeram, ... Journal of molecular biology 378 (2), 375-386, 2008 | 92 | 2008 |
The importance of valency in enhancing the import and cell routing potential of protein transduction domain-containing molecules M Sung, GMK Poon, J Gariépy Biochimica et Biophysica Acta (BBA)-Biomembranes 1758 (3), 355-363, 2006 | 80 | 2006 |
Structure-dependent inhibition of the ETS-family transcription factor PU.1 by novel heterocyclic diamidines M Munde, S Wang, A Kumar, CE Stephens, AA Farahat, DW Boykin, ... Nucleic acids research, gkt955, 2013 | 77 | 2013 |
Quantitative investigation of protein–nucleic acid interactions by biosensor surface Plasmon resonance S Wang, GMK Poon, WD Wilson DNA-Protein Interactions: Principles and Protocols, 313-332, 2015 | 43 | 2015 |
Base coupling in sequence-specific site recognition by the ETS domain of murine PU. 1 GMK Poon, RB Macgregor Jr Journal of molecular biology 328 (4), 805-819, 2003 | 43 | 2003 |
Explicit formulation of titration models for isothermal titration calorimetry GMK Poon Analytical biochemistry 400 (2), 229-236, 2010 | 41 | 2010 |
Mechanistic Heterogeneity in Site Recognition by the Structurally Homologous DNA-Binding Domains of the ETS-Family Transcription Factors Ets-1 and PU.1 S Wang, MH Linde, M Munde, VD Carvalho, WD Wilson, GMK Poon Journal of Biological Chemistry, jbc. M114. 575340, 2014 | 40 | 2014 |
Constrained chromatin accessibility in PU. 1-mutated agammaglobulinemia patients C Le Coz, DN Nguyen, C Su, BE Nolan, AV Albrecht, S Xhani, D Sun, ... Journal of Experimental Medicine 218 (7), e20201750, 2021 | 38 | 2021 |
Pharmacologic efficacy of PU. 1 inhibition by heterocyclic dications: a mechanistic analysis DC Stephens, HM Kim, A Kumar, AA Farahat, DW Boykin, GM Poon Nucleic acids research 44 (9), 4005-4013, 2016 | 37 | 2016 |
A rapid and universal tandem‐purification strategy for recombinant proteins AJ McCluskey, GMK Poon, J Gariépy Protein Science 16 (12), 2726-2732, 2007 | 37 | 2007 |
Sequence discrimination by DNA-binding domain of ETS family transcription factor PU. 1 is linked to specific hydration of protein-DNA interface GMK Poon Journal of Biological Chemistry 287 (22), 18297-18307, 2012 | 36 | 2012 |
Differential sensitivity to methylated DNA by ETS-family transcription factors is intrinsically encoded in their DNA-binding domains DC Stephens, GMK Poon Nucleic acids research 44 (18), 8671-8681, 2016 | 35 | 2016 |
Probing the electrostatics and pharmacological modulation of sequence-specific binding by the DNA-binding domain of the ETS family transcription factor PU. 1: a binding … M Munde, GMK Poon, WD Wilson Journal of molecular biology 425 (10), 1655-1669, 2013 | 35 | 2013 |
Tandem dimerization of the human p53 tetramerization domain stabilizes a primary dimer intermediate and dramatically enhances its oligomeric stability GMK Poon, RD Brokx, M Sung, J Gariépy Journal of molecular biology 365 (4), 1217-1231, 2007 | 34 | 2007 |