Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders KM Doyle, D Kennedy, AM Gorman, S Gupta, SJM Healy, A Samali Journal of cellular and molecular medicine 15 (10), 2025-2039, 2011 | 379 | 2011 |
Polyamines in the brain: distribution, biological interactions, and their potential therapeutic role in brain ischaemia J Li, KM Doyle, T Tatlisumak Current medicinal chemistry 14 (17), 1807-1813, 2007 | 73 | 2007 |
Platelet-rich emboli in cerebral large vessel occlusion are associated with a large artery atherosclerosis source S Fitzgerald, D Dai, S Wang, A Douglas, R Kadirvel, KF Layton, ... Stroke 50 (7), 1907-1910, 2019 | 69 | 2019 |
Orbit image analysis machine learning software can be used for the histological quantification of acute ischemic stroke blood clots S Fitzgerald, S Wang, D Dai, DH Murphree Jr, A Pandit, A Douglas, ... PloS one 14 (12), e0225841, 2019 | 67 | 2019 |
Association between clot composition and stroke origin in mechanical thrombectomy patients: analysis of the Stroke Thromboembolism Registry of Imaging and Pathology W Brinjikji, RG Nogueira, P Kvamme, KF Layton, JED Almandoz, ... Journal of neurointerventional surgery 13 (7), 594-598, 2021 | 56 | 2021 |
Platelet-rich clots as identified by Martius Scarlet Blue staining are isodense on NCCT ST Fitzgerald, S Wang, D Dai, A Douglas, R Kadirvel, MJ Gounis, J Chueh, ... Journal of neurointerventional surgery 11 (11), 1145-1149, 2019 | 54 | 2019 |
Per-pass analysis of acute ischemic stroke clots: impact of stroke etiology on extracted clot area and histological composition S Fitzgerald, R Rossi, OM Mereuta, D Jabrah, A Okolo, A Douglas, SM Gil, ... Journal of neurointerventional surgery 13 (12), 1111-1116, 2021 | 52 | 2021 |
Comparison of various N-methyl-D-aspartate receptor antagonists in a model of short-term memory and on overt behaviour KM Doyle, S Feerick, DL Kirkby, A Eddleston, GA Higgins Behavioural pharmacology 9 (8), 671-681, 1998 | 51 | 1998 |
Characterisation of a functional polyamine site on rat mast cells: association with a NMDA receptor macrocomplex WM Purcell, KM Doyle, C Westgate, CK Atterwill Journal of neuroimmunology 65 (1), 49-53, 1996 | 51 | 1996 |
Platelet-rich emboli are associated with von Willebrand factor levels and have poorer revascularization outcomes A Douglas, S Fitzgerald, OM Mereuta, R Rossi, S O'Leary, A Pandit, ... Journal of neurointerventional surgery 12 (6), 557-562, 2020 | 50 | 2020 |
Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner K Mnich, LA Carleton, ET Kavanagh, KM Doyle, A Samali, AM Gorman Cell death & disease 5 (5), e1202-e1202, 2014 | 50 | 2014 |
Histological stroke clot analysis after thrombectomy: technical aspects and recommendations S Staessens, S Fitzgerald, T Andersson, F Clarençon, F Denorme, ... International Journal of Stroke 15 (5), 467-476, 2020 | 48 | 2020 |
Studying stroke thrombus composition after thrombectomy: what can we learn? S Staessens, O François, W Brinjikji, KM Doyle, P Vanacker, T Andersson, ... Stroke 52 (11), 3718-3727, 2021 | 46 | 2021 |
The administration of rtPA before mechanical thrombectomy in acute ischemic stroke patients is associated with a significant reduction of the retrieved clot area but it does … R Rossi, S Fitzgerald, S Molina, OM Mereuta, A Douglas, A Pandit, ... Journal of thrombosis and thrombolysis 51, 545-551, 2021 | 43 | 2021 |
HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis D Kennedy, K Mnich, D Oommen, R Chakravarthy, L Almeida-Souza, ... Cell Death & Disease 8 (8), e3026-e3026, 2017 | 40 | 2017 |
Detection, diagnosis and treatment of acute ischemic stroke: current and future perspectives S Patil, R Rossi, D Jabrah, K Doyle Frontiers in medical technology 4, 748949, 2022 | 36 | 2022 |
Recent advances in psychoneuroimmunology: Inflammation in psychiatric disorders M Debnath, K Doyle, C Langan, C McDonald, B Leonard, D Cannon Translational Neuroscience 2 (2), 121-137, 2011 | 36 | 2011 |
Functionality of NGF-protected PC12 cells following exposure to 6-hydroxydopamine ET Kavanagh, JP Loughlin, KR Herbert, P Dockery, A Samali, KM Doyle, ... Biochemical and biophysical research communications 351 (4), 890-895, 2006 | 33 | 2006 |
Correlation of imaging and histopathology of thrombi in acute ischemic stroke with etiology and outcome S Fitzgerald, OM Mereuta, KM Doyle, DF Kallmes, W Brinjikji Journal of neurosurgical sciences 63 (3), 292, 2019 | 32 | 2019 |
The pre-ischaemic neuroprotective effect of a novel polyamine antagonist, N1-dansyl-spermine in a permanent focal cerebral ischaemia model in mice J Li, MC Henman, KM Doyle, D Strbian, BP Kirby, T Tatlisumak, GG Shaw Brain research 1029 (1), 84-92, 2004 | 29 | 2004 |