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David Clynes
David Clynes
PI
在 oncology.ox.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX
D Clynes, C Jelinska, B Xella, H Ayyub, C Scott, M Mitson, S Taylor, ...
Nature communications 6 (1), 7538, 2015
3052015
Molecular basis for the recognition of phosphorylated and phosphoacetylated histone h3 by 14-3-3
N Macdonald, JPI Welburn, MEM Noble, A Nguyen, MB Yaffe, D Clynes, ...
Molecular cell 20 (2), 199-211, 2005
2912005
Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin
S Eustermann, JC Yang, MJ Law, R Amos, LM Chapman, C Jelinska, ...
Nature structural & molecular biology 18 (7), 777-782, 2011
2262011
The chromatin remodeller ATRX: a repeat offender in human disease
D Clynes, DR Higgs, RJ Gibbons
Trends in biochemical sciences 38 (9), 461-466, 2013
1502013
The chromatin remodelling factor ATRX suppresses R‐loops in transcribed telomeric repeats
DTT Nguyen, HPJ Voon, B Xella, C Scott, D Clynes, C Babbs, H Ayyub, ...
EMBO reports 18 (6), 914-928, 2017
1322017
ATRX dysfunction induces replication defects in primary mouse cells
D Clynes, C Jelinska, B Xella, H Ayyub, S Taylor, M Mitson, CZ Bachrati, ...
PloS one 9 (3), e92915, 2014
1242014
14-3-3 interaction with histone H3 involves a dual modification pattern of phosphoacetylation
W Walter, D Clynes, Y Tang, R Marmorstein, J Mellor, SL Berger
Molecular and cellular biology, 2008
1102008
A glimpse into the epigenetic landscape of gene regulation
J Mellor, P Dudek, D Clynes
Current opinion in genetics & development 18 (2), 116-122, 2008
852008
ATRX and the replication of structured DNA
D Clynes, RJ Gibbons
Current opinion in genetics & development 23 (3), 289-294, 2013
592013
Lysine acetylation controls local protein conformation by influencing proline isomerization
FS Howe, I Boubriak, MJ Sale, A Nair, D Clynes, A Grijzenhout, ...
Molecular cell 55 (5), 733-744, 2014
452014
JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint response
E Chen, JS Ahn, CE Massie, D Clynes, AL Godfrey, J Li, HJ Park, ...
Proceedings of the National Academy of Sciences 111 (42), 15190-15195, 2014
442014
Nucleosome remodeling and transcriptional repression are distinct functions of Isw1 in Saccharomyces cerevisiae
M Pinskaya, A Nair, D Clynes, A Morillon, J Mellor
Molecular and cellular biology, 2009
302009
Alternative lengthening of telomeres in pediatric cancer: mechanisms to therapies
T Kent, D Gracias, S Shepherd, D Clynes
Frontiers in Oncology 9, 1518, 2020
212020
Alternative lengthening of telomeres: lessons to be learned from telomeric DNA double-strand break repair
T Kent, D Clynes
Genes 12 (11), 1734, 2021
102021
Induction of the alternative lengthening of telomeres pathway by trapping of proteins on DNA
AM Rose, T Goncalves, S Cunniffe, HEB Geiller, T Kent, S Shepherd, ...
Nucleic Acids Research 51 (13), 6509-6527, 2023
72023
Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma negatively regulates telomere length
M Kliszczak, D Moralli, JD Jankowska, P Bryjka, L Subha Meem, ...
Frontiers in Cell and Developmental Biology 11, 1175069, 2023
22023
Loss of FAM111B protease mutated in hereditary fibrosing poikiloderma syndrome negatively regulates telomere length
M Kliszczak, D Moralli, JD Jankowska, P Bryjka, LS Meem, T Goncalves, ...
bioRxiv, 2023.01. 22.525054, 2023
12023
Induction of the ALT pathway requires loss of ATRX-DAXX in concert with genotoxic lesions at telomeres
D Clynes, T Goncalves, T Kent, S Shepherd, S Cunniffe, S Kim, ...
12021
REACTIVE OXYGEN SPECIES, PROTEIN TRAPPING AND CANCER: NOVEL INSIGHTS FROM IN VITRO STUDIES
A Rose, T Goncalves, T Ma, A Rose, S Cunniffe, T Humphrey, ...
PEDIATRIC BLOOD & CANCER 70, 2023
2023
NAR Breakthrough Article Induction of the alternative lengthening of telomeres
AM Rose, T Goncalves, S Cunniffe, HEB Geiller, T Kent, S Shepherd, ...
Nucleic Acids Research, 6509-6527, 2023
2023
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