FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription M Lupien, J Eeckhoute, CA Meyer, Q Wang, Y Zhang, W Li, JS Carroll, ... Cell 132 (6), 958-970, 2008 | 1109 | 2008 |
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer Q Wang, W Li, Y Zhang, X Yuan, K Xu, J Yu, Z Chen, R Beroukhim, ... Cell 138 (2), 245-256, 2009 | 1060 | 2009 |
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 640 | 2014 |
Genomic hallmarks of localized, non-indolent prostate cancer M Fraser, VY Sabelnykova, TN Yamaguchi, LE Heisler, J Livingstone, ... Nature 541 (7637), 359-364, 2017 | 603 | 2017 |
Nucleosome dynamics define transcriptional enhancers HH He, CA Meyer, H Shin, ST Bailey, G Wei, Q Wang, Y Zhang, K Xu, ... Nature genetics 42 (4), 343-347, 2010 | 549 | 2010 |
Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy X Lan, DJ Jörg, FMG Cavalli, LM Richards, LV Nguyen, RJ Vanner, ... Nature 549 (7671), 227-232, 2017 | 432 | 2017 |
Positive cross-regulatory loop ties GATA-3 to estrogen receptor α expression in breast cancer J Eeckhoute, EK Keeton, M Lupien, SA Krum, JS Carroll, M Brown Cancer research 67 (13), 6477-6483, 2007 | 418 | 2007 |
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer SR Setlur, KD Mertz, Y Hoshida, F Demichelis, M Lupien, S Perner, ... Journal of the National Cancer Institute 100 (11), 815-825, 2008 | 390 | 2008 |
Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits O Corradin, A Saiakhova, B Akhtar-Zaidi, L Myeroff, J Willis, ... Genome research 24 (1), 1-13, 2014 | 383 | 2014 |
Epigenomic enhancer profiling defines a signature of colon cancer B Akhtar-Zaidi, R Cowper-Sal· lari, O Corradin, A Saiakhova, CF Bartels, ... Science 336 (6082), 736-739, 2012 | 374 | 2012 |
Breast cancer risk–associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression R Cowper-Sal· lari, X Zhang, JB Wright, SD Bailey, MD Cole, J Eeckhoute, ... Nature genetics 44 (11), 1191-1198, 2012 | 330 | 2012 |
A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies C Bahr, L Von Paleske, VV Uslu, S Remeseiro, N Takayama, SW Ng, ... Nature 553 (7689), 515-520, 2018 | 294 | 2018 |
Risk SNP-mediated promoter-enhancer switching drives prostate cancer through lncRNA PCAT19 JT Hua, M Ahmed, H Guo, Y Zhang, S Chen, F Soares, J Lu, S Zhou, ... Cell 174 (3), 564-575. e18, 2018 | 293 | 2018 |
Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers AA Sérandour, S Avner, F Percevault, F Demay, M Bizot, ... Genome research 21 (4), 555-565, 2011 | 271 | 2011 |
Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer D Brocks, Y Assenov, S Minner, O Bogatyrova, R Simon, C Koop, ... Cell reports 8 (3), 798-806, 2014 | 269 | 2014 |
PharmacoGx: an R package for analysis of large pharmacogenomic datasets P Smirnov, Z Safikhani, N El-Hachem, D Wang, A She, C Olsen, ... Bioinformatics 32 (8), 1244-1246, 2016 | 264 | 2016 |
Functional enhancers shape extrachromosomal oncogene amplifications AR Morton, N Dogan-Artun, ZJ Faber, G MacLeod, CF Bartels, MS Piazza, ... Cell 179 (6), 1330-1341. e13, 2019 | 256 | 2019 |
CARM1 regulates estrogen-stimulated breast cancer growth through up-regulation of E2F1 S Frietze, M Lupien, PA Silver, M Brown Cancer research 68 (1), 301-306, 2008 | 245 | 2008 |
Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors C Hu, A Diévart, M Lupien, E Calvo, G Tremblay, P Jolicoeur The American journal of pathology 168 (3), 973-990, 2006 | 231 | 2006 |
Integrated (epi)-genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumors J Torchia, B Golbourn, S Feng, KC Ho, P Sin-Chan, A Vasiljevic, ... Cancer cell 30 (6), 891-908, 2016 | 230 | 2016 |