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Martin McMahon
Martin McMahon
Cumming-Presidential Professor of Cancer Biology, Huntsman Cancer Institute, Univ. of Utah
在 hci.utah.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
SP Thayer, MP di Magliano, PW Heiser, CM Nielsen, DJ Roberts, ...
Nature 425 (6960), 851-856, 2003
19542003
Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK
A Minden, A Lin, M McMahon, C Lange-Carter, B Dérijard, RJ Davis, ...
Science 266 (5191), 1719-1723, 1994
13701994
BrafV600E cooperates with Pten loss to induce metastatic melanoma
D Dankort, DP Curley, RA Cartlidge, B Nelson, AN Karnezis, ...
Nature genetics 41 (5), 544-552, 2009
13502009
Senescence of human fibroblasts induced by oncogenic Raf
J Zhu, D Woods, M McMahon, JM Bishop
Genes & development 12 (19), 2997-3007, 1998
10261998
Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond
M Holderfield, MM Deuker, F McCormick, M McMahon
Nature Reviews Cancer 14 (7), 455-467, 2014
8762014
Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance
M Das Thakur, F Salangsang, AS Landman, WR Sellers, NK Pryer, ...
Nature 494 (7436), 251-255, 2013
8742013
Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells
RL Friedman, SP Manly, M McMahon, IM Kerr, GR Stark
Cell 38 (3), 745-755, 1984
8571984
Raf-Induced Proliferation or Cell Cycle Arrest Is Determined by the Level of Raf Activity with Arrest Mediated by p21Cip1
D Woods, D Parry, H Cherwinski, E Bosch, E Lees, M McMahon
Molecular and cellular biology 17 (9), 5598-5611, 1997
7911997
A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors
D Dankort, E Filenova, M Collado, M Serrano, K Jones, M McMahon
Genes & development 21 (4), 379-384, 2007
5882007
An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background
D Mitra, X Luo, A Morgan, J Wang, MP Hoang, J Lo, CR Guerrero, ...
Nature 491 (7424), 449-453, 2012
5612012
Protective autophagy elicited by RAF→ MEK→ ERK inhibition suggests a treatment strategy for RAS-driven cancers
CG Kinsey, SA Camolotto, AM Boespflug, KP Guillen, M Foth, A Truong, ...
Nature medicine 25 (4), 620-627, 2019
5602019
The Hippo effector YAP promotes resistance to RAF-and MEK-targeted cancer therapies
L Lin, AJ Sabnis, E Chan, V Olivas, L Cade, E Pazarentzos, S Asthana, ...
Nature genetics 47 (3), 250-256, 2015
5332015
Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation
M Onishi, T Nosaka, K Misawa, ALF Mui, D Gorman, M McMahon, ...
Molecular and cellular biology 18 (7), 3871-3879, 1998
5001998
Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of BrafV600E–Driven Lung Tumors
AM Strohecker, JY Guo, G Karsli-Uzunbas, SM Price, GJ Chen, R Mathew, ...
Cancer discovery 3 (11), 1272-1285, 2013
4622013
Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF
S Ries, C Biederer, D Woods, O Shifman, S Shirasawa, T Sasazuki, ...
Cell 103 (2), 321-330, 2000
4482000
β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas
WE Damsky, DP Curley, M Santhanakrishnan, LE Rosenbaum, JT Platt, ...
Cancer cell 20 (6), 741-754, 2011
4222011
Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase
ML Samuels, MJ Weber, JM Bishop, M McMahon
Molecular and cellular biology, 1993
4191993
Raf induces TGFβ production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells
K Lehmann, E Janda, CE Pierreux, M Rytömaa, A Schulze, M McMahon, ...
Genes & development 14 (20), 2610-2622, 2000
3852000
A central role for RAF→ MEK→ ERK signaling in the genesis of pancreatic ductal adenocarcinoma
EA Collisson, CL Trejo, JM Silva, S Gu, JE Korkola, LM Heiser, ...
Cancer discovery 2 (8), 685-693, 2012
3402012
Analysis of the transcriptional program induced by Raf in epithelial cells
A Schulze, K Lehmann, HBJ Jefferies, M McMahon, J Downward
Genes & development 15 (8), 981-994, 2001
3392001
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