Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity N Modhiran, D Watterson, DA Muller, AK Panetta, DP Sester, L Liu, ... Science translational medicine 7 (304), 304ra142-304ra142, 2015 | 505 | 2015 |
Mechanisms of immune evasion induced by a complex of dengue virus and preexisting enhancing antibodies S Ubol, W Phuklia, S Kalayanarooj, N Modhiran The Journal of infectious diseases 201 (6), 923-935, 2010 | 235 | 2010 |
The many faces of the flavivirus NS1 protein offer a multitude of options for inhibitor design D Watterson, N Modhiran, PR Young Antiviral research 130, 7-18, 2016 | 147 | 2016 |
Systems serology detects functionally distinct coronavirus antibody features in children and elderly KJ Selva, CE Van De Sandt, MM Lemke, CY Lee, SK Shoffner, BY Chua, ... Nature communications 12 (1), 2037, 2021 | 139 | 2021 |
Dengue virus NS1 protein activates immune cells via TLR4 but not TLR2 or TLR6 N Modhiran, D Watterson, A Blumenthal, AG Baxter, PR Young, KJ Stacey Immunology and cell biology 95 (5), 491-495, 2017 | 117 | 2017 |
Subversion of innate defenses by the interplay between DENV and pre-existing enhancing antibodies: TLRs signaling collapse N Modhiran, S Kalayanarooj, S Ubol PLoS neglected tropical diseases 4 (12), e924, 2010 | 117 | 2010 |
Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial KJ Chappell, FL Mordant, Z Li, DK Wijesundara, P Ellenberg, ... The Lancet Infectious Diseases 21 (10), 1383-1394, 2021 | 99 | 2021 |
A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses AA Amarilla, JDJ Sng, R Parry, JM Deerain, JR Potter, YX Setoh, ... Nature Communications 12 (1), 3431, 2021 | 97 | 2021 |
A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus J Hobson-Peters, JJ Harrison, D Watterson, JE Hazlewood, LJ Vet, ... Science translational medicine 11 (522), eaax7888, 2019 | 94 | 2019 |
SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein EA Albornoz, AA Amarilla, N Modhiran, S Parker, XX Li, DK Wijesundara, ... Molecular psychiatry 28 (7), 2878-2893, 2023 | 83 | 2023 |
A broadly protective antibody that targets the flavivirus NS1 protein N Modhiran, H Song, L Liu, C Bletchly, L Brillault, AA Amarilla, X Xu, J Qi, ... Science 371 (6525), 190-194, 2021 | 80 | 2021 |
Synthetic heparan sulfate mimetic pixatimod (PG545) potently inhibits SARS-CoV-2 by disrupting the spike–ACE2 interaction SE Guimond, CJ Mycroft-West, NS Gandhi, JA Tree, TT Le, CM Spalluto, ... ACS central science 8 (5), 527-545, 2022 | 78 | 2022 |
Osteoclastogenesis induced by CHIKV-infected fibroblast-like synoviocytes: a possible interplay between synoviocytes and monocytes/macrophages in CHIKV-induced arthralgia/arthritis W Phuklia, J Kasisith, N Modhiran, E Rodpai, M Thannagith, ... Virus research 177 (2), 179-188, 2013 | 78 | 2013 |
Preclinical development of a molecular clamp‐stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2 D Watterson, DK Wijesundara, N Modhiran, FL Mordant, Z Li, ... Clinical & translational immunology 10 (4), e1269, 2021 | 54 | 2021 |
Determinants of Zika virus host tropism uncovered by deep mutational scanning YX Setoh, AA Amarilla, NYG Peng, RE Griffiths, J Carrera, ME Freney, ... Nature microbiology 4 (5), 876-887, 2019 | 54 | 2019 |
Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity nanobody G Valenzuela Nieto, R Jara, D Watterson, N Modhiran, AA Amarilla, ... Scientific reports 11 (1), 3318, 2021 | 50 | 2021 |
An optimized high-throughput immuno-plaque assay for SARS-CoV-2 AA Amarilla, N Modhiran, YX Setoh, NYG Peng, JDJ Sng, B Liang, ... Frontiers in microbiology 12, 625136, 2021 | 47 | 2021 |
No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing N Smits, J Rasmussen, GO Bodea, AA Amarilla, P Gerdes, ... Cell reports 36 (7), 2021 | 44 | 2021 |
Riboflavin and ultraviolet light: impact on dengue virus infectivity HM Faddy, JJ Fryk, D Watterson, PR Young, N Modhiran, DA Muller, ... Vox sanguinis 111 (3), 235-241, 2016 | 41 | 2016 |
Complete protection by a single-dose skin patch–delivered SARS-CoV-2 spike vaccine CLD McMillan, JJY Choo, A Idris, A Supramaniam, N Modhiran, ... Science advances 7 (44), eabj8065, 2021 | 39 | 2021 |