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Naphak Modhiran
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引用次数
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Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity
N Modhiran, D Watterson, DA Muller, AK Panetta, DP Sester, L Liu, ...
Science translational medicine 7 (304), 304ra142-304ra142, 2015
5052015
Mechanisms of immune evasion induced by a complex of dengue virus and preexisting enhancing antibodies
S Ubol, W Phuklia, S Kalayanarooj, N Modhiran
The Journal of infectious diseases 201 (6), 923-935, 2010
2352010
The many faces of the flavivirus NS1 protein offer a multitude of options for inhibitor design
D Watterson, N Modhiran, PR Young
Antiviral research 130, 7-18, 2016
1472016
Systems serology detects functionally distinct coronavirus antibody features in children and elderly
KJ Selva, CE Van De Sandt, MM Lemke, CY Lee, SK Shoffner, BY Chua, ...
Nature communications 12 (1), 2037, 2021
1392021
Dengue virus NS1 protein activates immune cells via TLR4 but not TLR2 or TLR6
N Modhiran, D Watterson, A Blumenthal, AG Baxter, PR Young, KJ Stacey
Immunology and cell biology 95 (5), 491-495, 2017
1172017
Subversion of innate defenses by the interplay between DENV and pre-existing enhancing antibodies: TLRs signaling collapse
N Modhiran, S Kalayanarooj, S Ubol
PLoS neglected tropical diseases 4 (12), e924, 2010
1172010
Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial
KJ Chappell, FL Mordant, Z Li, DK Wijesundara, P Ellenberg, ...
The Lancet Infectious Diseases 21 (10), 1383-1394, 2021
992021
A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses
AA Amarilla, JDJ Sng, R Parry, JM Deerain, JR Potter, YX Setoh, ...
Nature Communications 12 (1), 3431, 2021
972021
A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus
J Hobson-Peters, JJ Harrison, D Watterson, JE Hazlewood, LJ Vet, ...
Science translational medicine 11 (522), eaax7888, 2019
942019
SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein
EA Albornoz, AA Amarilla, N Modhiran, S Parker, XX Li, DK Wijesundara, ...
Molecular psychiatry 28 (7), 2878-2893, 2023
832023
A broadly protective antibody that targets the flavivirus NS1 protein
N Modhiran, H Song, L Liu, C Bletchly, L Brillault, AA Amarilla, X Xu, J Qi, ...
Science 371 (6525), 190-194, 2021
802021
Synthetic heparan sulfate mimetic pixatimod (PG545) potently inhibits SARS-CoV-2 by disrupting the spike–ACE2 interaction
SE Guimond, CJ Mycroft-West, NS Gandhi, JA Tree, TT Le, CM Spalluto, ...
ACS central science 8 (5), 527-545, 2022
782022
Osteoclastogenesis induced by CHIKV-infected fibroblast-like synoviocytes: a possible interplay between synoviocytes and monocytes/macrophages in CHIKV-induced arthralgia/arthritis
W Phuklia, J Kasisith, N Modhiran, E Rodpai, M Thannagith, ...
Virus research 177 (2), 179-188, 2013
782013
Preclinical development of a molecular clamp‐stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2
D Watterson, DK Wijesundara, N Modhiran, FL Mordant, Z Li, ...
Clinical & translational immunology 10 (4), e1269, 2021
542021
Determinants of Zika virus host tropism uncovered by deep mutational scanning
YX Setoh, AA Amarilla, NYG Peng, RE Griffiths, J Carrera, ME Freney, ...
Nature microbiology 4 (5), 876-887, 2019
542019
Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity nanobody
G Valenzuela Nieto, R Jara, D Watterson, N Modhiran, AA Amarilla, ...
Scientific reports 11 (1), 3318, 2021
502021
An optimized high-throughput immuno-plaque assay for SARS-CoV-2
AA Amarilla, N Modhiran, YX Setoh, NYG Peng, JDJ Sng, B Liang, ...
Frontiers in microbiology 12, 625136, 2021
472021
No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing
N Smits, J Rasmussen, GO Bodea, AA Amarilla, P Gerdes, ...
Cell reports 36 (7), 2021
442021
Riboflavin and ultraviolet light: impact on dengue virus infectivity
HM Faddy, JJ Fryk, D Watterson, PR Young, N Modhiran, DA Muller, ...
Vox sanguinis 111 (3), 235-241, 2016
412016
Complete protection by a single-dose skin patch–delivered SARS-CoV-2 spike vaccine
CLD McMillan, JJY Choo, A Idris, A Supramaniam, N Modhiran, ...
Science advances 7 (44), eabj8065, 2021
392021
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