Petabase-scale sequence alignment catalyses viral discovery RC Edgar, B Taylor, V Lin, T Altman, P Barbera, D Meleshko, D Lohr, ... Nature 602 (7895), 142-147, 2022 | 318 | 2022 |
Peripheral regions of natural hammerhead ribozymes greatly increase their self‐cleavage activity M De la Peña, S Gago, R Flores The EMBO journal, 2003 | 296 | 2003 |
The ubiquitous hammerhead ribozyme C Hammann, A Luptak, J Perreault, M De La Peña Rna 18 (5), 871-885, 2012 | 198 | 2012 |
Viroids: the minimal non-coding RNAs with autonomous replication R Flores, S Delgado, ME Gas, A Carbonell, D Molina, S Gago, ... FEBS letters 567 (1), 42-48, 2004 | 151 | 2004 |
Ubiquitous presence of the hammerhead ribozyme motif along the tree of life M de la Peña, I García-Robles Rna 16 (10), 1943-1950, 2010 | 118 | 2010 |
Viroid replication: rolling-circles, enzymes and ribozymes R Flores, ME Gas, D Molina-Serrano, MÁ Nohales, A Carbonell, S Gago, ... Viruses 1 (2), 317-334, 2009 | 113 | 2009 |
Intronic hammerhead ribozymes are ultraconserved in the human genome M De La Peña, I García‐Robles EMBO reports 11 (9), 711-716, 2010 | 112 | 2010 |
Mapping the molecular determinant of pathogenicity in a hammerhead viroid: A tetraloop within the in vivo branched RNA conformation M De la Peña, B Navarro, R Flores Proceedings of the National Academy of Sciences 96 (17), 9960-9965, 1999 | 107 | 1999 |
Pepper chat fruit viroid: biological and molecular properties of a proposed new species of the genus Pospiviroid JTJ Verhoeven, CCC Jansen, JW Roenhorst, R Flores, M De la Peña Virus Research 144 (1-2), 209-214, 2009 | 87 | 2009 |
Structural insights into the mechanism and evolution of the vaccinia virus mRNA cap N7 methyl‐transferase M De la Pena, OJP Kyrieleis, S Cusack The EMBO Journal 26 (23), 4913-4925, 2007 | 86 | 2007 |
Three-way RNA junctions with remote tertiary contacts: A recurrent and highly versatile fold M De La Peña, D Dufour, J Gallego RNA 15 (11), 1949-1964, 2009 | 82 | 2009 |
A kissing-loop interaction in a hammerhead viroid RNA critical for its in vitro folding and in vivo viability S Gago, M De la Peña, R Flores Rna 11 (7), 1073-1083, 2005 | 78 | 2005 |
Chrysanthemum chlorotic mottle viroid RNA: dissection of the pathogenicity determinant and comparative fitness of symptomatic and non-symptomatic variants M De la Pena, R Flores Journal of Molecular Biology 321 (3), 411-421, 2002 | 69 | 2002 |
EFFECT OF DELETERIOUS MUTATION‐ACCUMULATION ON THE FITNESS OF RNA BACTERIOPHAGE MS2 M Peña, SF Elena, A Moya Evolution 54 (2), 686-691, 2000 | 69 | 2000 |
Hammerhead ribozyme structure and function in plant RNA replication R Flores, C Hernandez, M de la Peña, A Vera, JA Daros Methods in enzymology 341, 540-552, 2001 | 64 | 2001 |
Genomic Analysis of Terpene Synthase Family and Functional Characterization of Seven Sesquiterpene Synthases from Citrus sinensis B Alquézar, A Rodríguez, M de la Peña, L Peña Frontiers in Plant Science 8, 1481, 2017 | 63 | 2017 |
Structure–function analysis of the ribozymes of chrysanthemum chlorotic mottle viroid: a loop–loop interaction motif conserved in most natural hammerheads D Dufour, M de la Pena, S Gago, R Flores, J Gallego Nucleic acids research 37 (2), 368-381, 2009 | 63 | 2009 |
The hammerhead ribozyme: a long history for a short RNA M De la Peña, I García-Robles, A Cervera Molecules 22 (1), 78, 2017 | 62 | 2017 |
Crystal structure of vaccinia virus mRNA capping enzyme provides insights into the mechanism and evolution of the capping apparatus OJP Kyrieleis, J Chang, M de la Peña, S Shuman, S Cusack Structure 22 (3), 452-465, 2014 | 60 | 2014 |
Phylogenetic analysis of viroid and viroid-like satellite RNAs from plants: a reassessment SF Elena, J Dopazo, M de la Pena, R Flores, TO Diener, A Moya Journal of Molecular Evolution 53, 155-159, 2001 | 60 | 2001 |