The secret life of CFTR as a calcium‐activated chloride channel A Billet, JW Hanrahan The Journal of physiology 591 (21), 5273-5278, 2013 | 102 | 2013 |
Low free drug concentration prevents inhibition of F508del CFTR functional expression by the potentiator VX‐770 (ivacaftor) E Matthes, J Goepp, GW Carlile, Y Luo, K Dejgaard, A Billet, R Robert, ... British journal of pharmacology 173 (3), 459-470, 2016 | 77 | 2016 |
Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR) A Billet, Y Luo, H Balghi, JW Hanrahan Journal of Biological Chemistry 288 (30), 21815-21823, 2013 | 54 | 2013 |
Pendrin mediates bicarbonate secretion and enhances cystic fibrosis transmembrane conductance regulator function in airway surface epithelia D Kim, J Huang, A Billet, A Abu-Arish, J Goepp, E Matthes, MA Tewfik, ... American journal of respiratory cell and molecular biology 60 (6), 705-716, 2019 | 45 | 2019 |
The dual phosphodiesterase 3 and 4 inhibitor RPL554 stimulates CFTR and ciliary beating in primary cultures of bronchial epithelia MJ Turner, E Matthes, A Billet, AJ Ferguson, DY Thomas, SH Randell, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 310 (1 …, 2016 | 42 | 2016 |
The rescue of F508del-CFTR by elexacaftor/tezacaftor/ivacaftor (Trikafta) in human airway epithelial cells is underestimated due to the presence of ivacaftor F Becq, S Mirval, T Carrez, M Lévêque, A Billet, C Coraux, E Sage, ... European Respiratory Journal 59 (2), 2022 | 32 | 2022 |
Development of automated patch clamp technique to investigate CFTR chloride channel function A Billet, L Froux, JW Hanrahan, F Becq Frontiers in pharmacology 8, 195, 2017 | 31 | 2017 |
Regulation of the cystic fibrosis transmembrane conductance regulator anion channel by tyrosine phosphorylation A Billet, Y Jia, T Jensen, JR Riordan, JW Hanrahan The FASEB Journal 29 (9), 3945, 2015 | 31 | 2015 |
CFTR: effect of ICL2 and ICL4 amino acids in close spatial proximity on the current properties of the channel A Billet, JP Mornon, M Jollivet, P Lehn, I Callebaut, F Becq Journal of Cystic Fibrosis 12 (6), 737-745, 2013 | 29 | 2013 |
Potential sites of CFTR activation by tyrosine kinases A Billet, Y Jia, TJ Jensen, YX Hou, XB Chang, JR Riordan, JW Hanrahan Channels 10 (3), 247-251, 2016 | 20 | 2016 |
Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity L Froux, A Elbahnsi, B Boucherle, A Billet, N Baatallah, B Hoffmann, ... European Journal of Medicinal Chemistry 190, 112116, 2020 | 15 | 2020 |
C terminus of nucleotide binding domain 1 contains critical features for cystic fibrosis transmembrane conductance regulator trafficking and activation A Billet, P Melin, M Jollivet, JP Mornon, I Callebaut, F Becq Journal of Biological Chemistry 285 (29), 22132-22140, 2010 | 15 | 2010 |
Identification of a novel water-soluble activator of wild-type and F508del CFTR: GPact-11a J Bertrand, B Boucherle, A Billet, P Melin-Heschel, L Dannhoffer, ... European Respiratory Journal 36 (2), 311-322, 2010 | 14 | 2010 |
Stimulation of wild-type, F508del-and G551D-CFTR chloride channels by non-toxic modified pyrrolo [2, 3-b] pyrazine derivatives L Dannhoffer, A Billet, M Jollivet, P Melin-Heschel, C Faveau, F Becq Frontiers in pharmacology 2, 48, 2011 | 10 | 2011 |
Functional and pharmacological characterization of the rare CFTR mutation W361R A Billet, A Elbahnsi, M Jollivet-Souchet, B Hoffmann, JP Mornon, ... Frontiers in Pharmacology 11, 295, 2020 | 9 | 2020 |
Pendrin mediates bicarbonate secretion and enhances CFTR function in airway surface epithelia D Kim, J Huang, A Billet, A Abu-Arish, J Goepp, E Matthes, MA Tewfik, ... American Journal of Respiratory Cell and Molecular Biology 60 (6), 705-716, 2019 | 7 | 2019 |
Ostrowski 1051 LE, Abbott-Banner K, and Hanrahan JW MJ Turner, E Matthes, A Billet, AJ Ferguson, DY Thomas, SH Randell The dual phosphodiesterase 3, 0 | 5 | |
The mechanism underlying toxicity of a venom peptide against insects reveals how ants are master at disrupting membranes S Ascoët, A Touchard, N Téné, B Lefranc, J Leprince, F Paquet, ... Iscience 26 (3), 2023 | 4 | 2023 |
Modulating the cystic fibrosis transmembrane regulator and the development of new precision drugs L Froux, A Billet, F Becq Expert Review of Precision Medicine and Drug Development 3 (6), 357-370, 2018 | 3 | 2018 |
Discovery of an insect neuroactive helix ring peptide from ant venom V Barassé, L Jouvensal, G Boy, A Billet, S Ascoët, B Lefranc, J Leprince, ... Toxins 15 (10), 600, 2023 | 2 | 2023 |