Transcriptome-based network analysis reveals a spectrum model of human macrophage activation J Xue, SV Schmidt, J Sander, A Draffehn, W Krebs, I Quester, D De Nardo, ... Immunity 40 (2), 274-288, 2014 | 2204 | 2014 |
The adaptor ASC has extracellular and'prionoid'activities that propagate inflammation BS Franklin, L Bossaller, D De Nardo, JM Ratter, A Stutz, G Engels, ... Nature immunology 15 (8), 727-737, 2014 | 818 | 2014 |
TDP-43 triggers mitochondrial DNA release via mPTP to activate cGAS/STING in ALS CH Yu, S Davidson, CR Harapas, JB Hilton, MJ Mlodzianoski, ... Cell 183 (3), 636-649. e18, 2020 | 585 | 2020 |
Toll-like receptors: activation, signalling and transcriptional modulation D De Nardo Cytokine 74 (2), 181-189, 2015 | 510 | 2015 |
High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3 D De Nardo, LI Labzin, H Kono, R Seki, SV Schmidt, M Beyer, D Xu, ... Nature immunology 15 (2), 152-160, 2014 | 460 | 2014 |
NLRP3 inflammasomes link inflammation and metabolic disease D De Nardo, E Latz Trends in immunology 32 (8), 373-379, 2011 | 446 | 2011 |
Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner SA Conos, KW Chen, D De Nardo, H Hara, L Whitehead, G Núñez, ... Proceedings of the National Academy of Sciences 114 (6), E961-E969, 2017 | 405 | 2017 |
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming S Zimmer, A Grebe, SS Bakke, N Bode, B Halvorsen, T Ulas, M Skjelland, ... Science translational medicine 8 (333), 333ra50-333ra50, 2016 | 346 | 2016 |
The inflammasomes and autoinflammatory syndromes L Broderick, D De Nardo, BS Franklin, HM Hoffman, E Latz Annual Review of Pathology: Mechanisms of Disease 10 (1), 395-424, 2015 | 317 | 2015 |
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation SL Masters, V Lagou, I Jéru, PJ Baker, L Van Eyck, DA Parry, D Lawless, ... Science translational medicine 8 (332), 332ra45-332ra45, 2016 | 303 | 2016 |
TBK1 and IKKε act redundantly to mediate STING-induced NF-κB responses in myeloid cells KR Balka, C Louis, TL Saunders, AM Smith, DJ Calleja, DB D’Silva, ... Cell reports 31 (1), 2020 | 275 | 2020 |
New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease D De Nardo, CM De Nardo, E Latz The American journal of pathology 184 (1), 42-54, 2014 | 225 | 2014 |
The mitochondrial apoptotic effectors BAX/BAK activate caspase-3 and-7 to trigger NLRP3 inflammasome and caspase-8 driven IL-1β activation JE Vince, D De Nardo, W Gao, AJ Vince, C Hall, K McArthur, D Simpson, ... Cell reports 25 (9), 2339-2353. e4, 2018 | 191 | 2018 |
Understanding early TLR signaling through the Myddosome KR Balka, D De Nardo Journal of leukocyte biology 105 (2), 339-351, 2019 | 170 | 2019 |
A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean Fever F Moghaddas, R Llamas, D De Nardo, H Martinez-Banaclocha, ... Annals of the rheumatic diseases 76 (12), 2085-2094, 2017 | 157 | 2017 |
Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β ML Kim, JJ Chae, YH Park, D De Nardo, RA Stirzaker, HJ Ko, H Tye, ... Journal of Experimental Medicine 212 (6), 927-938, 2015 | 142 | 2015 |
Signaling crosstalk during sequential TLR4 and TLR9 activation amplifies the inflammatory response of mouse macrophages D De Nardo, CM De Nardo, T Nguyen, JA Hamilton, GM Scholz The Journal of Immunology 183 (12), 8110-8118, 2009 | 125 | 2009 |
ATF3 is a key regulator of macrophage IFN responses LI Labzin, SV Schmidt, SL Masters, M Beyer, W Krebs, K Klee, R Stahl, ... The Journal of Immunology 195 (9), 4446-4455, 2015 | 118 | 2015 |
Flexible usage and interconnectivity of diverse cell death pathways protect against intracellular infection M Doerflinger, Y Deng, P Whitney, R Salvamoser, S Engel, AJ Kueh, L Tai, ... Immunity 53 (3), 533-547. e7, 2020 | 114 | 2020 |
Interleukin-1 receptor–associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling D De Nardo, KR Balka, YC Gloria, VR Rao, E Latz, SL Masters Journal of Biological Chemistry 293 (39), 15195-15207, 2018 | 108 | 2018 |