Drug repurposing: progress, challenges and recommendations S Pushpakom, F Iorio, PA Eyers, KJ Escott, S Hopper, A Wells, A Doig, ... Nature reviews Drug discovery 18 (1), 41-58, 2019 | 3766 | 2019 |
Improved glycaemia correlates with liver fat reduction in obese, type 2 diabetes, patients given glucagon-like peptide-1 (GLP-1) receptor agonists DJ Cuthbertson, A Irwin, CJ Gardner, C Daousi, T Purewal, N Furlong, ... PloS one 7 (12), e50117, 2012 | 291 | 2012 |
The SLCO1B1 rs4149032 Polymorphism Is Highly Prevalent in South Africans and Is Associated with Reduced Rifampin Concentrations: Dosing Implications E Chigutsa, ME Visser, EC Swart, P Denti, S Pushpakom, D Egan, ... Antimicrobial agents and chemotherapy 55 (9), 4122-4127, 2011 | 170 | 2011 |
Cytochrome P450 testing for prescribing antipsychotics in adults with schizophrenia: systematic review and meta-analyses N Fleeman, Y Dundar, R Dickson, A Jorgensen, S Pushpakom, C McLeod, ... The pharmacogenomics journal 11 (1), 1-14, 2011 | 159 | 2011 |
Genetic Variants of ABCC10, a Novel Tenofovir Transporter, Are Associated With Kidney Tubular Dysfunction SP Pushpakom, NJ Liptrott, S Rodríguez-Nóvoa, P Labarga, V Soriano, ... Journal of Infectious Diseases 204 (1), 145-153, 2011 | 144 | 2011 |
The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia A Giannoudis, L Wang, AL Jorgensen, G Xinarianos, A Davies, ... Blood, The Journal of the American Society of Hematology 121 (4), 628-637, 2013 | 92 | 2013 |
A pragmatic randomized controlled trial of thiopurine methyltransferase genotyping prior to azathioprine treatment: the TARGET study WG Newman, K Payne, K Tricker, SA Roberts, E Fargher, S Pushpakom, ... Pharmacogenomics 12 (6), 815-826, 2011 | 91 | 2011 |
The clinical effectiveness and cost-effectiveness of testing for cytochrome P450 polymorphisms in patients with schizophrenia treated with antipsychotics: a systematic review … N Fleeman, C McLeod, A Bagust, S Beale, A Boland, Y Dundar, ... Health Technology Assessment (Winchester, England) 14 (3), 1-157, iii, 2010 | 84 | 2010 |
Stephens' detection and evaluation of adverse drug reactions: principles and practice J Talbot, JK Aronson John Wiley & Sons, 2011 | 61 | 2011 |
Association of ABCC10 polymorphisms with nevirapine plasma concentrations in the German Competence Network for HIV/AIDS NJ Liptrott, S Pushpakom, C Wyen, G Fätkenheuer, C Hoffmann, S Mauss, ... Pharmacogenetics and genomics 22 (1), 10-19, 2012 | 56 | 2012 |
Simultaneous pharmacogenetics-based population pharmacokinetic analysis of darunavir and ritonavir in HIV-infected patients J Moltó, G Xinarianos, C Miranda, S Pushpakom, S Cedeño, B Clotet, ... Clinical pharmacokinetics 52, 543-553, 2013 | 48 | 2013 |
Microfluidic platform for single nucleotide polymorphism genotyping of the thiopurine S-methyltransferase gene to evaluate risk for adverse drug events J Chowdhury, GV Kagiala, S Pushpakom, J Lauzon, A Makin, A Atrazhev, ... The Journal of Molecular Diagnostics 9 (4), 521-529, 2007 | 35 | 2007 |
Genetic analysis of thiopurine methyltransferase polymorphism in the Jordanian population N Hakooz, T Arafat, D Payne, W Ollier, S Pushpakom, J Andrews, ... European journal of clinical pharmacology 66, 999-1003, 2010 | 30 | 2010 |
Quantitative analysis of plasma DNA in severe acute pancreatitis A Bagul, S Pushpakom, J Boylan, W Newman, AK Siriwardena Jop 7 (6), 602-607, 2006 | 25 | 2006 |
Cardiovascular drugs and COVID‐19 clinical outcomes: a living systematic review and meta‐analysis IG Asiimwe, S Pushpakom, RM Turner, R Kolamunnage‐Dona, ... British journal of clinical pharmacology 87 (12), 4534-4545, 2021 | 23 | 2021 |
Telmisartan and insulin resistance in HIV (TAILoR): protocol for a dose-ranging phase II randomised open-labelled trial of telmisartan as a strategy for the reduction of … SP Pushpakom, C Taylor, R Kolamunnage-Dona, C Spowart, J Vora, ... BMJ open 5 (10), e009566, 2015 | 23 | 2015 |
Natural history of azathioprine-associated lymphopenia in inflammatory bowel disease patients: a prospective observational study A Al Rifai, N Prasad, E Shuttleworth, H McBurney, S Pushpakom, ... European journal of gastroenterology & hepatology 23 (2), 153-158, 2011 | 22 | 2011 |
TAILoR (TelmisArtan and InsuLin Resistance in Human Immunodeficiency Virus [HIV]): an adaptive-design, dose-ranging phase IIb randomized trial of telmisartan for the reduction … S Pushpakom, R Kolamunnage-Dona, C Taylor, T Foster, C Spowart, ... Clinical Infectious Diseases 70 (10), 2062-2072, 2020 | 16 | 2020 |
Cardiovascular drugs and COVID‐19 clinical outcomes: a systematic review and meta‐analysis of randomized controlled trials IG Asiimwe, SP Pushpakom, RM Turner, R Kolamunnage‐Dona, ... British journal of clinical pharmacology 88 (8), 3577-3599, 2022 | 13 | 2022 |
Nilotinib-induced metabolic dysfunction: insights from a translational study using in vitro adipocyte models and patient cohorts S Sadiq, E Owen, T Foster, K Knight, L Wang, M Pirmohamed, RE Clark, ... leukemia 33 (7), 1810-1814, 2019 | 13 | 2019 |